Clinical trials data
Verbal Learning in depression and bipolar disorder trials: 178 registered studies
Every registered depression and bipolar disorder study on ClinicalTrials.gov that names Verbal Learning in an outcome measure: how often it is a primary outcome, the tests named with it, how large the studies are and when they measure it.
- Registered depression and bipolar disorder studies name it in an outcome measure
- 178
- Name it in a primary outcome, 29%
- 51 of 178
Tests named in the same studies
- 1
Trail Making Test69 studies, 21 as a primary outcome
- 2
Verbal Fluency56 studies, 17 as a primary outcome
- 3
Digit Span Test48 studies, 12 as a primary outcome
- 4
Symbol Coding44 studies, 15 as a primary outcome
- 5
Stroop Color-Word Test33 studies, 5 as a primary outcome
- 6
Continuous Performance Test15 studies, 8 as a primary outcome
- 7
Category Fluency15 studies, 4 as a primary outcome
- 8
Card Sorting Test (Berg)14 studies, 3 as a primary outcome
- 9
Letter-Number Sequencing Task11 studies, 6 as a primary outcome
- 10
Rapid Visual Information Processing10 studies, 5 as a primary outcome
A test as a primary outcomeOnly in secondary or other outcomes
Studies by start year
A test as a primary outcomeOnly in secondary or other outcomes
Show as a table
| Start year | Studies | A test as a primary outcome |
|---|---|---|
| 2000 | 0 | 0 |
| 2001 | 0 | 0 |
| 2002 | 0 | 0 |
| 2003 | 2 | 1 |
| 2004 | 2 | 1 |
| 2005 | 5 | 3 |
| 2006 | 4 | 0 |
| 2007 | 2 | 1 |
| 2008 | 5 | 2 |
| 2009 | 2 | 0 |
| 2010 | 7 | 0 |
| 2011 | 5 | 1 |
| 2012 | 4 | 1 |
| 2013 | 4 | 2 |
| 2014 | 9 | 0 |
| 2015 | 16 | 9 |
| 2016 | 8 | 3 |
| 2017 | 15 | 6 |
| 2018 | 8 | 3 |
| 2019 | 7 | 2 |
| 2020 | 5 | 1 |
| 2021 | 8 | 4 |
| 2022 | 7 | 2 |
| 2023 | 12 | 2 |
| 2024 | 9 | 1 |
| 2025 | 19 | 3 |
| 2026 | 12 | 3 |
Phases and study sizes
By phase
- Early phase 13 studies, 1 as a primary outcome
- Phase 15 studies, 2 as a primary outcome
- Phase 1/25 studies, 0 as a primary outcome
- Phase 221 studies, 4 as a primary outcome
- Phase 2/34 studies, 0 as a primary outcome
- Phase 319 studies, 4 as a primary outcome
- Phase 416 studies, 5 as a primary outcome
- Not applicable85 studies, 23 as a primary outcome
- Observational20 studies, 12 as a primary outcome
Participants per study
- Phase 262 median, 40 to 105
- Phase 381 median, 41 to 366
- Phase 453 median, 29 to 75
- Not applicable60 median, 28 to 95
- Observational110 median, 66 to 219
Show as a table
| Phase | Studies with a size | Median | Middle half |
|---|---|---|---|
| Phase 2 | 21 | 62 | 40 to 105 |
| Phase 3 | 18 | 81 | 41 to 366 |
| Phase 4 | 16 | 53 | 29 to 75 |
| Not applicable | 80 | 60 | 28 to 95 |
| Observational | 20 | 110 | 66 to 219 |
When depression and bipolar disorder trials measure it
Latest time point of each outcome
- Within a day11 outcomes, 7 as a primary outcome
- Up to 4 weeks27 outcomes, 8 as a primary outcome
- 1 to 3 months73 outcomes, 19 as a primary outcome
- 3 to 6 months28 outcomes, 7 as a primary outcome
- 6 to 12 months13 outcomes, 1 as a primary outcome
- 1 to 2 years7 outcomes, 2 as a primary outcome
- Over 2 years5 outcomes, 3 as a primary outcome
- No duration given14 outcomes, 4 as a primary outcome
A test as a primary outcomeOnly in secondary or other outcomes
164 of the 178 outcome measures give a duration. A single visit counts as within a day.
Status, results, interventions and countries
Status
- Recruiting37 studies, 7 as a primary outcome
- Not yet recruiting1 studies, 1 as a primary outcome
- Active, not recruiting12 studies, 3 as a primary outcome
- Completed87 studies, 28 as a primary outcome
- Stopped early20 studies, 3 as a primary outcome
- Status unknown21 studies, 9 as a primary outcome
What they test
- Behavioral38 studies, 11 as a primary outcome
- Drug69 studies, 17 as a primary outcome
- Device41 studies, 12 as a primary outcome
- Dietary supplement9 studies, 2 as a primary outcome
- Procedure6 studies, 1 as a primary outcome
- Diagnostic test1 studies, 0 as a primary outcome
- Biological2 studies, 0 as a primary outcome
- Radiation2 studies, 1 as a primary outcome
- Combination product2 studies, 0 as a primary outcome
- Genetic1 studies, 1 as a primary outcome
- Other28 studies, 8 as a primary outcome
- None given11 studies, 7 as a primary outcome
Intervention types as registered. A study can list several; observational studies often list none.
Where their sites are
- United States73 studies, 24 as a primary outcome
- Canada25 studies, 4 as a primary outcome
- Spain12 studies, 4 as a primary outcome
- France11 studies, 3 as a primary outcome
- Germany11 studies, 4 as a primary outcome
- Denmark10 studies, 7 as a primary outcome
- United Kingdom10 studies, 4 as a primary outcome
- Austria6 studies, 3 as a primary outcome
- China6 studies, 1 as a primary outcome
- Australia5 studies, 3 as a primary outcome
- Brazil5 studies, 2 as a primary outcome
- Netherlands5 studies, 2 as a primary outcome
39 countries in all. A study with sites in several counts in each; 7 list no site.
Reported results
Completed studies with results posted on ClinicalTrials.gov, a results paper the registry links to the study, or both.
Completed depression and bipolar disorder studies that name Verbal Learning: 58 of 87, 67%
Every completed study with a cognitive outcome: 3,626 of 7,953, 46%
| Results | Completed depression and bipolar disorder studies that name Verbal Learning | Every completed study |
|---|---|---|
| Results on ClinicalTrials.gov and a paper | 15, 17% | 776, 10% |
| Results on ClinicalTrials.gov only | 22, 25% | 1,139, 14% |
| A results paper only | 21, 24% | 1,711, 22% |
| Neither | 29, 33% | 4,327, 54% |
The 178 studies
178 studies match. 51 name Verbal Learning in a primary outcome. Median size 60 participants. Median time to the primary outcome: 11 weeks.
Loading 178 studies; the filters turn on when they arrive.
2026 is partly planned starts. Not shown: 1 that started before 2000.
Show as a table
| Start year | Studies | As a primary outcome |
|---|---|---|
| 2000 | 0 | 0 |
| 2001 | 0 | 0 |
| 2002 | 0 | 0 |
| 2003 | 2 | 1 |
| 2004 | 2 | 1 |
| 2005 | 5 | 3 |
| 2006 | 4 | 0 |
| 2007 | 2 | 1 |
| 2008 | 5 | 2 |
| 2009 | 2 | 0 |
| 2010 | 7 | 0 |
| 2011 | 5 | 1 |
| 2012 | 4 | 1 |
| 2013 | 4 | 2 |
| 2014 | 9 | 0 |
| 2015 | 16 | 9 |
| 2016 | 8 | 3 |
| 2017 | 15 | 6 |
| 2018 | 8 | 3 |
| 2019 | 7 | 2 |
| 2020 | 5 | 1 |
| 2021 | 8 | 4 |
| 2022 | 7 | 2 |
| 2023 | 12 | 2 |
| 2024 | 9 | 1 |
| 2025 | 19 | 3 |
| 2026 | 12 | 3 |
Library tests named most
Largest condition groups
Phases
Participants
Lead sponsor: industry 13, NIH 1, other 164. Interventional 158, observational 20.
As a primary outcomeSecondary or other outcomeVerbal Learning
The studies, newest registration first
Each number opens the study's record on ClinicalTrials.gov.
| Study | Start | Phase | Conditions | Participants | Lead sponsor | Status | Library tests named, with the latest time point |
|---|---|---|---|---|---|---|---|
| NCT07848477 | Start2026 | PhaseNot applicable | ConditionsDepression and bipolar disorder | Participants60 | Lead sponsorOther | StatusRecruiting | Library tests named
|
| NCT07664852 | Start2026 | PhasePhase 3 | ConditionsDepression and bipolar disorder | Participants126 | Lead sponsorOther | StatusRecruiting | Library tests named
|
| NCT07652775 | Start2026 | PhaseNot applicable | ConditionsMild cognitive impairment, Depression and bipolar disorder | Participants45 | Lead sponsorOther | StatusRecruiting | Library tests named
|
| NCT07633626 | Start2026 | PhaseObservational | ConditionsDepression and bipolar disorder, Cancer | Participants24 | Lead sponsorOther | StatusRecruiting | Library tests named
|
| NCT07611773 | Start2026 | PhaseNot applicable | ConditionsDepression and bipolar disorder | Participants270 | Lead sponsorIndustry | StatusRecruiting | Library tests named
|
| NCT07610369 | Start2026 | PhasePhase 2 | ConditionsParkinson's disease, Depression and bipolar disorder | Participants40 | Lead sponsorOther | StatusRecruiting | Library tests named
|
| NCT07590999 | Start2025 | PhaseNot applicable | ConditionsDepression and bipolar disorder | Participants106 | Lead sponsorOther | StatusRecruiting | Library tests named
|
| NCT07550140 | Start2026 | PhaseNot applicable | ConditionsDepression and bipolar disorder, Sleep and sleep disorders, Anxiety, PTSD and OCD | Participants60 | Lead sponsorOther | StatusRecruiting | Library tests named
|
| NCT07508215 | Start2026 | PhaseNot applicable | ConditionsDepression and bipolar disorder | Participants120 | Lead sponsorOther | StatusRecruiting | Library tests named
|
| NCT07506070 | Start2026 | PhaseNot applicable | ConditionsSchizophrenia and psychosis, Depression and bipolar disorder, Autism, Anxiety, PTSD and OCD | Participants160 | Lead sponsorOther | StatusNot yet recruiting | Library tests named
|
| NCT07504120 | Start2025 | PhaseNot applicable | ConditionsMultiple sclerosis, Depression and bipolar disorder, Aging, frailty and exercise, Pain and fatigue | Participants50 | Lead sponsorOther | StatusRecruiting | Library tests named
|
| NCT07492537 | Start2025 | PhaseNot applicable | ConditionsDepression and bipolar disorder, Cardiovascular disease | Participants100 | Lead sponsorOther | StatusRecruiting | Library tests named
|
| NCT07474974 | Start2026 | PhaseNot applicable | ConditionsDepression and bipolar disorder | Participants44 | Lead sponsorOther | StatusRecruiting | Library tests named
|
| NCT07404085 | Start2025 | PhaseNot applicable | ConditionsSchizophrenia and psychosis, Depression and bipolar disorder | Participants160 | Lead sponsorOther | StatusRecruiting | Library tests named
|
| NCT07402356 | Start2025 | PhaseObservational | ConditionsDementia and Alzheimer's, Mild cognitive impairment, Depression and bipolar disorder | Participants140 | Lead sponsorOther | StatusRecruiting | Library tests named
|
| NCT07376018 | Start2026 | PhaseNot applicable | ConditionsDepression and bipolar disorder | Participants60 | Lead sponsorOther | StatusRecruiting | Library tests named
|
| NCT07350226 | Start2025 | PhaseNot applicable | ConditionsDepression and bipolar disorder | Participants86 | Lead sponsorOther | StatusActive, not recruiting | Library tests named
|
| NCT07324070 | Start2026 | PhaseNot applicable | ConditionsDepression and bipolar disorder | Participants50 | Lead sponsorOther | StatusRecruiting | Library tests named
|
| NCT07309302 | Start2025 | PhaseNot applicable | ConditionsDepression and bipolar disorder, Anxiety, PTSD and OCD | Participants64 | Lead sponsorOther | StatusRecruiting | Library tests named
|
| NCT06914284 | Start2024 | PhaseObservational | ConditionsDepression and bipolar disorder | Participants30 | Lead sponsorOther | StatusRecruiting | Library tests named
|
| NCT06913309 | Start2025 | PhaseNot applicable | ConditionsDepression and bipolar disorder | Participants168 | Lead sponsorOther | StatusRecruiting | Library tests named
|
| NCT06897670 | Start2025 | PhaseObservational | ConditionsMild cognitive impairment, Depression and bipolar disorder | Participants200 | Lead sponsorOther | StatusRecruiting | Library tests named
|
| NCT06854367 | Start2025 | PhaseNot applicable | ConditionsDepression and bipolar disorder | Participants280 | Lead sponsorOther | StatusRecruiting | Library tests named
|
| NCT06796712 | Start2025 | PhaseNot applicable | ConditionsDepression and bipolar disorder, Anxiety, PTSD and OCD | Participants55 | Lead sponsorOther | StatusCompleted | Library tests named
|
| NCT06785012 | Start2024 | PhasePhase 2 | ConditionsDepression and bipolar disorder | Participants105 | Lead sponsorIndustry | StatusCompleted | Library tests named
|
Questions, answered from the data
How many depression and bipolar disorder trials use Verbal Learning?
178 registered depression and bipolar disorder studies on ClinicalTrials.gov name it in an outcome measure, 51 of them in a primary outcome: 14% of the condition's 1,247 studies with a cognitive outcome, against 11% of all of them. It is the 2nd most named test in depression and bipolar disorder trials.
Which tests do depression and bipolar disorder trials use with Verbal Learning?
The Trail Making Test (69 studies), Verbal Fluency (56 studies) and the Digit Span Test (48 studies).
How many participants do phase 2 depression and bipolar disorder trials that use Verbal Learning enroll?
Half of the phase 2 studies that name it enroll 62 participants or fewer, and the middle half enroll 40 to 105. 21 of them give a size.
When do depression and bipolar disorder trials measure Verbal Learning?
Half of the primary outcomes that name Verbal Learning are measured within 11 weeks of the start, and the middle half from 4 weeks to 4 months. 47 primary outcomes give a duration.
How many completed depression and bipolar disorder trials that use Verbal Learning have reported results?
58 of the 87 completed studies that name it, 67%, have reported results: 37 posted them on ClinicalTrials.gov, 36 have a results paper linked to the registry record, and 15 did both. The other 29 show neither. Of all completed studies with a cognitive outcome, 46% have reported results.
How the studies are counted
For each test family, the census runs ClinicalTrials.gov's own outcome search for the family's names and reads every study first posted by the day the family was counted. These studies were read on 10 November 2026. A study counts once on a page, however many tests it names. Counts for a test cover every version of the task under any of its names, so a page can count studies that used a commercial version.
The census adds two things to each record and changes nothing in it: which outcome list names the test (primary, then secondary, then other), and the condition groups, matched on the study's condition names and MeSH terms. A study can fall in several groups; one whose only condition is cognitive impairment or decline falls in “Cognitive impairment and decline”. Studies that name only instruments outside the library count in every total and share but are not listed.
A second read on 10 November 2026 added each study's overall status, whether results are posted, its intervention types, the countries of its sites and the time frame of the outcome that names each test. A time frame counts by the latest time point it names: “Baseline, 12 and 24 weeks” is 24 weeks, a single visit is within a day, and one that names no duration, such as “end of treatment”, is left out of the timings.
A third read on 10 November 2026 added the papers the registry links to each study: those its sponsor lists as reporting results, and those PubMed links to it through the study's NCT number. A study has a results paper when one of them came out in or after the month of its primary completion and PubMed does not class it as a protocol, review or comment. A paper that never gives the NCT number is not linked, so some studies counted as reporting neither did publish.
Source: ClinicalTrials.gov, a database of the U.S. National Library of Medicine, which does not endorse these pages. Every study line is in the data release 2.1.0, and the explorer's own file is clinical-trials-studies.json.
The census counts Verbal Learning and Grocery Trip Game as one test family, so this page counts their studies together.
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