Clinical trials data
Verbal Learning in substance use and addiction trials: 77 registered studies
Every registered substance use and addiction study on ClinicalTrials.gov that names Verbal Learning in an outcome measure: how often it is a primary outcome, the tests named with it, how large the studies are and when they measure it.
- Registered substance use and addiction studies name it in an outcome measure
- 77
- Name it in a primary outcome, 43%
- 33 of 77
Tests named in the same studies
- 1
Continuous Performance Test16 studies, 6 as a primary outcome
- 2
Trail Making Test15 studies, 6 as a primary outcome
- 3
Digit Span Test14 studies, 6 as a primary outcome
- 4
Symbol Coding11 studies, 4 as a primary outcome
- 5
Stop-Signal Task9 studies, 6 as a primary outcome
- 6
Verbal Fluency9 studies, 5 as a primary outcome
- 7
Card Sorting Test (Berg)7 studies, 4 as a primary outcome
- 8
Stroop Color-Word Test7 studies, 3 as a primary outcome
- 9
Go/No-Go Task6 studies, 3 as a primary outcome
- 10
N-Back Task6 studies, 3 as a primary outcome
A test as a primary outcomeOnly in secondary or other outcomes
Studies by start year
A test as a primary outcomeOnly in secondary or other outcomes
Show as a table
| Start year | Studies | A test as a primary outcome |
|---|---|---|
| 2000 | 0 | 0 |
| 2001 | 1 | 0 |
| 2002 | 0 | 0 |
| 2003 | 1 | 1 |
| 2004 | 0 | 0 |
| 2005 | 2 | 0 |
| 2006 | 2 | 1 |
| 2007 | 1 | 1 |
| 2008 | 2 | 1 |
| 2009 | 2 | 1 |
| 2010 | 6 | 2 |
| 2011 | 0 | 0 |
| 2012 | 1 | 0 |
| 2013 | 3 | 3 |
| 2014 | 3 | 0 |
| 2015 | 3 | 3 |
| 2016 | 4 | 3 |
| 2017 | 4 | 2 |
| 2018 | 5 | 1 |
| 2019 | 7 | 3 |
| 2020 | 1 | 1 |
| 2021 | 9 | 6 |
| 2022 | 3 | 0 |
| 2023 | 3 | 2 |
| 2024 | 4 | 1 |
| 2025 | 5 | 1 |
| 2026 | 3 | 0 |
Phases and study sizes
By phase
- Early phase 17 studies, 3 as a primary outcome
- Phase 114 studies, 8 as a primary outcome
- Phase 1/23 studies, 1 as a primary outcome
- Phase 214 studies, 7 as a primary outcome
- Phase 34 studies, 1 as a primary outcome
- Phase 45 studies, 1 as a primary outcome
- Not applicable23 studies, 8 as a primary outcome
- Observational7 studies, 4 as a primary outcome
Participants per study
- Phase 135 median, 17 to 95
- Phase 269 median, 49 to 116
- Not applicable60 median, 46 to 90
Show as a table
| Phase | Studies with a size | Median | Middle half |
|---|---|---|---|
| Phase 1 | 14 | 35 | 17 to 95 |
| Phase 2 | 14 | 69 | 49 to 116 |
| Not applicable | 21 | 60 | 46 to 90 |
When substance use and addiction trials measure it
Latest time point of each outcome
- Within a day22 outcomes, 12 as a primary outcome
- Up to 4 weeks16 outcomes, 7 as a primary outcome
- 1 to 3 months18 outcomes, 4 as a primary outcome
- 3 to 6 months10 outcomes, 4 as a primary outcome
- 6 to 12 months3 outcomes, 1 as a primary outcome
- 1 to 2 years1 outcomes, 1 as a primary outcome
- Over 2 years1 outcomes, 1 as a primary outcome
- No duration given6 outcomes, 3 as a primary outcome
A test as a primary outcomeOnly in secondary or other outcomes
71 of the 77 outcome measures give a duration. A single visit counts as within a day.
Status, results, interventions and countries
Status
- Recruiting16 studies, 7 as a primary outcome
- Not yet recruiting3 studies, 0 as a primary outcome
- Active, not recruiting2 studies, 1 as a primary outcome
- Completed45 studies, 24 as a primary outcome
- Stopped early8 studies, 1 as a primary outcome
- Status unknown3 studies, 0 as a primary outcome
What they test
- Behavioral18 studies, 9 as a primary outcome
- Drug51 studies, 24 as a primary outcome
- Device3 studies, 0 as a primary outcome
- Procedure1 studies, 1 as a primary outcome
- Diagnostic test1 studies, 0 as a primary outcome
- Other9 studies, 3 as a primary outcome
- None given3 studies, 1 as a primary outcome
Intervention types as registered. A study can list several; observational studies often list none.
Where their sites are
- United States54 studies, 27 as a primary outcome
- Canada10 studies, 1 as a primary outcome
- United Kingdom3 studies, 2 as a primary outcome
- Australia1 studies, 0 as a primary outcome
- Brazil1 studies, 0 as a primary outcome
- China1 studies, 1 as a primary outcome
- Czechia1 studies, 0 as a primary outcome
- Denmark1 studies, 0 as a primary outcome
- Netherlands1 studies, 1 as a primary outcome
- Spain1 studies, 0 as a primary outcome
10 countries in all. A study with sites in several counts in each; 4 list no site.
Reported results
Completed studies with results posted on ClinicalTrials.gov, a results paper the registry links to the study, or both.
Completed substance use and addiction studies that name Verbal Learning: 33 of 45, 73%
Every completed study with a cognitive outcome: 3,626 of 7,953, 46%
| Results | Completed substance use and addiction studies that name Verbal Learning | Every completed study |
|---|---|---|
| Results on ClinicalTrials.gov and a paper | 6, 13% | 776, 10% |
| Results on ClinicalTrials.gov only | 14, 31% | 1,139, 14% |
| A results paper only | 13, 29% | 1,711, 22% |
| Neither | 12, 27% | 4,327, 54% |
The 77 studies
77 studies match. 33 name Verbal Learning in a primary outcome. Median size 52 participants. Median time to the primary outcome: 4 weeks.
Loading 77 studies; the filters turn on when they arrive.
2026 is partly planned starts. Not shown: 1 that started before 2000 and 1 planned to start after 2026.
Show as a table
| Start year | Studies | As a primary outcome |
|---|---|---|
| 2000 | 0 | 0 |
| 2001 | 1 | 0 |
| 2002 | 0 | 0 |
| 2003 | 1 | 1 |
| 2004 | 0 | 0 |
| 2005 | 2 | 0 |
| 2006 | 2 | 1 |
| 2007 | 1 | 1 |
| 2008 | 2 | 1 |
| 2009 | 2 | 1 |
| 2010 | 6 | 2 |
| 2011 | 0 | 0 |
| 2012 | 1 | 0 |
| 2013 | 3 | 3 |
| 2014 | 3 | 0 |
| 2015 | 3 | 3 |
| 2016 | 4 | 3 |
| 2017 | 4 | 2 |
| 2018 | 5 | 1 |
| 2019 | 7 | 3 |
| 2020 | 1 | 1 |
| 2021 | 9 | 6 |
| 2022 | 3 | 0 |
| 2023 | 3 | 2 |
| 2024 | 4 | 1 |
| 2025 | 5 | 1 |
| 2026 | 3 | 0 |
Library tests named most
Largest condition groups
Phases
Participants
Lead sponsor: industry 3, other 74. Interventional 70, observational 7.
As a primary outcomeSecondary or other outcomeVerbal Learning
The studies, newest registration first
Each number opens the study's record on ClinicalTrials.gov.
| Study | Start | Phase | Conditions | Participants | Lead sponsor | Status | Library tests named, with the latest time point |
|---|---|---|---|---|---|---|---|
| NCT07886606 | Start2021 | PhaseEarly phase 1 | ConditionsSubstance use and addiction, Pain and fatigue | Participants34 | Lead sponsorOther | StatusRecruiting | Library tests named
|
| NCT07885085 | Start2027 | PhaseObservational | ConditionsMild cognitive impairment, Substance use and addiction, Delirium, surgery and intensive care, Pain and fatigue | Participants552 | Lead sponsorOther | StatusNot yet recruiting | Library tests named
|
| NCT07878130 | Start2026 | PhasePhase 2 | ConditionsSubstance use and addiction | Participants100 | Lead sponsorOther | StatusNot yet recruiting | Library tests named
|
| NCT07218471 | Start2026 | PhaseNot applicable | ConditionsSubstance use and addiction | Participants176 | Lead sponsorOther | StatusRecruiting | Library tests named
|
| NCT07160153 | Start2024 | PhaseObservational | ConditionsSubstance use and addiction | Participants29 | Lead sponsorOther | StatusRecruiting | Library tests named
|
| NCT07056894 | Start2026 | PhaseNot applicable | ConditionsSchizophrenia and psychosis, Substance use and addiction | Participants50 | Lead sponsorOther | StatusRecruiting | Library tests named
|
| NCT07001878 | Start2025 | PhasePhase 4 | ConditionsSchizophrenia and psychosis, Substance use and addiction | Participants24 | Lead sponsorOther | StatusRecruiting | Library tests named
|
| NCT06808048 | Start2025 | PhaseNot applicable | ConditionsSubstance use and addiction, Pain and fatigue | Participants180 | Lead sponsorOther | StatusRecruiting | Library tests named
|
| NCT06544291 | Start2024 | PhasePhase 2 | ConditionsSubstance use and addiction, Pain and fatigue | Participants147 | Lead sponsorOther | StatusRecruiting | Library tests named
|
| NCT06381180 | Start2025 | PhasePhase 1/2 | ConditionsSubstance use and addiction, Anxiety, PTSD and OCD | Participants500 | Lead sponsorOther | StatusRecruiting | Library tests named
|
| NCT06335407 | Start2025 | PhasePhase 1 | ConditionsSubstance use and addiction, Anxiety, PTSD and OCD | Participants10 | Lead sponsorOther | StatusRecruiting | Library tests named
|
| NCT05859347 | Start2023 | PhaseNot applicable | ConditionsSubstance use and addiction | Participants46 | Lead sponsorOther | StatusRecruiting | Library tests named
|
| NCT05822362 | Start2024 | PhasePhase 2 | ConditionsDementia and Alzheimer's, Mild cognitive impairment, Substance use and addiction | Participants236 | Lead sponsorOther | StatusRecruiting | Library tests named
|
| NCT05503147 | Start2022 | PhasePhase 1 | ConditionsAging, frailty and exercise, Substance use and addiction | Participants17 | Lead sponsorOther | StatusStatus unknown | Library tests named
|
| NCT05488509 | Start2023 | PhasePhase 2 | ConditionsSubstance use and addiction | Participants121 | Lead sponsorOther | StatusCompleted | Library tests named
|
| NCT05386862 | Start2022 | PhaseNot applicable | ConditionsSubstance use and addiction, Anxiety, PTSD and OCD | ParticipantsNot given | Lead sponsorOther | StatusStopped early | Library tests named
|
| NCT05210608 | Start2021 | PhaseNot applicable | ConditionsSubstance use and addiction | Participants13 | Lead sponsorOther | StatusCompleted | Library tests named
|
| NCT05188404 | Start2021 | PhaseObservational | ConditionsSubstance use and addiction | Participants326 | Lead sponsorOther | StatusCompleted | Library tests named
|
| NCT05170217 | Start2017 | PhaseNot applicable | ConditionsSubstance use and addiction | Participants46 | Lead sponsorOther | StatusCompleted | Library tests named
|
| NCT05160688 | Start2023 | PhaseNot applicable | ConditionsSubstance use and addiction | Participants146 | Lead sponsorOther | StatusCompleted | Library tests named
|
| NCT04998006 | Start2022 | PhaseObservational | ConditionsSubstance use and addiction | Participants77 | Lead sponsorOther | StatusCompleted | Library tests named
|
| NCT04935619 | Start2021 | PhaseNot applicable | ConditionsDepression and bipolar disorder, Substance use and addiction, Anxiety, PTSD and OCD | Participants52 | Lead sponsorOther | StatusRecruiting | Library tests named
|
| NCT04902092 | Start2019 | PhaseNot applicable | ConditionsCancer, Substance use and addiction | Participants65 | Lead sponsorOther | StatusCompleted | Library tests named
|
| NCT04855526 | Start2025 | PhaseEarly phase 1 | ConditionsSubstance use and addiction | Participants9 | Lead sponsorOther | StatusNot yet recruiting | Library tests named
|
| NCT04827056 | Start2021 | PhasePhase 1 | ConditionsSubstance use and addiction, Anxiety, PTSD and OCD | Participants10 | Lead sponsorOther | StatusCompleted | Library tests named
|
Questions, answered from the data
How many substance use and addiction trials use Verbal Learning?
77 registered substance use and addiction studies on ClinicalTrials.gov name it in an outcome measure, 33 of them in a primary outcome: 9% of the condition's 895 studies with a cognitive outcome, against 11% of all of them. It is the 6th most named test in substance use and addiction trials.
Which tests do substance use and addiction trials use with Verbal Learning?
The Continuous Performance Test (16 studies), the Trail Making Test (15 studies) and the Digit Span Test (14 studies).
How many participants do phase 2 substance use and addiction trials that use Verbal Learning enroll?
Half of the phase 2 studies that name it enroll 69 participants or fewer, and the middle half enroll 49 to 116. 14 of them give a size.
When do substance use and addiction trials measure Verbal Learning?
Half of the primary outcomes that name Verbal Learning are measured within 4 weeks of the start, and the middle half from the first day to 12 weeks. 30 primary outcomes give a duration.
How many completed substance use and addiction trials that use Verbal Learning have reported results?
33 of the 45 completed studies that name it, 73%, have reported results: 20 posted them on ClinicalTrials.gov, 19 have a results paper linked to the registry record, and 6 did both. The other 12 show neither. Of all completed studies with a cognitive outcome, 46% have reported results.
How the studies are counted
For each test family, the census runs ClinicalTrials.gov's own outcome search for the family's names and reads every study first posted by the day the family was counted. These studies were read on 10 November 2026. A study counts once on a page, however many tests it names. Counts for a test cover every version of the task under any of its names, so a page can count studies that used a commercial version.
The census adds two things to each record and changes nothing in it: which outcome list names the test (primary, then secondary, then other), and the condition groups, matched on the study's condition names and MeSH terms. A study can fall in several groups; one whose only condition is cognitive impairment or decline falls in “Cognitive impairment and decline”. Studies that name only instruments outside the library count in every total and share but are not listed.
A second read on 10 November 2026 added each study's overall status, whether results are posted, its intervention types, the countries of its sites and the time frame of the outcome that names each test. A time frame counts by the latest time point it names: “Baseline, 12 and 24 weeks” is 24 weeks, a single visit is within a day, and one that names no duration, such as “end of treatment”, is left out of the timings.
A third read on 10 November 2026 added the papers the registry links to each study: those its sponsor lists as reporting results, and those PubMed links to it through the study's NCT number. A study has a results paper when one of them came out in or after the month of its primary completion and PubMed does not class it as a protocol, review or comment. A paper that never gives the NCT number is not linked, so some studies counted as reporting neither did publish.
Source: ClinicalTrials.gov, a database of the U.S. National Library of Medicine, which does not endorse these pages. Every study line is in the data release 2.1.0, and the explorer's own file is clinical-trials-studies.json.
The census counts Verbal Learning and Grocery Trip Game as one test family, so this page counts their studies together.
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