Clinical trials data
Verbal Learning in pain and fatigue trials: 72 registered studies
Every registered pain and fatigue study on ClinicalTrials.gov that names Verbal Learning in an outcome measure: how often it is a primary outcome, the tests named with it, how large the studies are and when they measure it.
- Registered pain and fatigue studies name it in an outcome measure
- 72
- Name it in a primary outcome, 22%
- 16 of 72
Tests named in the same studies
- 1
Symbol Coding22 studies, 1 as a primary outcome
- 2
Trail Making Test21 studies, 5 as a primary outcome
- 3
Digit Span Test19 studies, 7 as a primary outcome
- 4
Verbal Fluency16 studies, 3 as a primary outcome
- 5
Stroop Color-Word Test11 studies, 3 as a primary outcome
- 6
Continuous Performance Test9 studies, 3 as a primary outcome
- 7
Paced Visual Serial Addition Test5 studies, 4 as a primary outcome
- 8
Go/No-Go Task3 studies, 1 as a primary outcome
- 9
Psychomotor Vigilance Task3 studies, 1 as a primary outcome
- 10
Category Fluency3 studies, 0 as a primary outcome
A test as a primary outcomeOnly in secondary or other outcomes
Studies by start year
A test as a primary outcomeOnly in secondary or other outcomes
Show as a table
| Start year | Studies | A test as a primary outcome |
|---|---|---|
| 2000 | 0 | 0 |
| 2001 | 0 | 0 |
| 2002 | 0 | 0 |
| 2003 | 0 | 0 |
| 2004 | 2 | 1 |
| 2005 | 0 | 0 |
| 2006 | 1 | 0 |
| 2007 | 1 | 0 |
| 2008 | 1 | 1 |
| 2009 | 0 | 0 |
| 2010 | 1 | 0 |
| 2011 | 0 | 0 |
| 2012 | 1 | 0 |
| 2013 | 3 | 1 |
| 2014 | 4 | 1 |
| 2015 | 2 | 2 |
| 2016 | 8 | 0 |
| 2017 | 4 | 0 |
| 2018 | 2 | 1 |
| 2019 | 1 | 0 |
| 2020 | 3 | 1 |
| 2021 | 4 | 3 |
| 2022 | 4 | 0 |
| 2023 | 7 | 2 |
| 2024 | 11 | 2 |
| 2025 | 6 | 1 |
| 2026 | 5 | 0 |
Phases and study sizes
By phase
- Early phase 13 studies, 2 as a primary outcome
- Phase 1/21 studies, 0 as a primary outcome
- Phase 218 studies, 1 as a primary outcome
- Phase 2/32 studies, 1 as a primary outcome
- Phase 37 studies, 1 as a primary outcome
- Not applicable30 studies, 6 as a primary outcome
- Observational11 studies, 5 as a primary outcome
Participants per study
- Phase 2120 median, 99 to 220
- Not applicable60 median, 38 to 99
- Observational100 median, 75 to 175
Show as a table
| Phase | Studies with a size | Median | Middle half |
|---|---|---|---|
| Phase 2 | 17 | 120 | 99 to 220 |
| Not applicable | 29 | 60 | 38 to 99 |
| Observational | 11 | 100 | 75 to 175 |
When pain and fatigue trials measure it
Latest time point of each outcome
- Within a day9 outcomes, 3 as a primary outcome
- Up to 4 weeks17 outcomes, 3 as a primary outcome
- 1 to 3 months18 outcomes, 4 as a primary outcome
- 3 to 6 months16 outcomes, 4 as a primary outcome
- 6 to 12 months4 outcomes, 0 as a primary outcome
- 1 to 2 years3 outcomes, 1 as a primary outcome
- Over 2 years1 outcomes, 0 as a primary outcome
- No duration given4 outcomes, 1 as a primary outcome
A test as a primary outcomeOnly in secondary or other outcomes
68 of the 72 outcome measures give a duration. A single visit counts as within a day.
Status, results, interventions and countries
Status
- Recruiting19 studies, 4 as a primary outcome
- Not yet recruiting3 studies, 0 as a primary outcome
- Active, not recruiting2 studies, 1 as a primary outcome
- Completed39 studies, 9 as a primary outcome
- Stopped early2 studies, 0 as a primary outcome
- Status unknown7 studies, 2 as a primary outcome
What they test
- Behavioral12 studies, 2 as a primary outcome
- Drug29 studies, 5 as a primary outcome
- Device9 studies, 2 as a primary outcome
- Dietary supplement3 studies, 1 as a primary outcome
- Procedure2 studies, 0 as a primary outcome
- Diagnostic test3 studies, 1 as a primary outcome
- Radiation2 studies, 1 as a primary outcome
- Combination product2 studies, 0 as a primary outcome
- Other15 studies, 4 as a primary outcome
- None given6 studies, 3 as a primary outcome
Intervention types as registered. A study can list several; observational studies often list none.
Where their sites are
- United States39 studies, 9 as a primary outcome
- Türkiye5 studies, 1 as a primary outcome
- Canada3 studies, 0 as a primary outcome
- Denmark3 studies, 1 as a primary outcome
- Germany3 studies, 1 as a primary outcome
- Sweden3 studies, 1 as a primary outcome
- Brazil2 studies, 1 as a primary outcome
- China2 studies, 1 as a primary outcome
- Italy2 studies, 0 as a primary outcome
- Netherlands2 studies, 1 as a primary outcome
- Norway2 studies, 0 as a primary outcome
- Egypt1 studies, 0 as a primary outcome
22 countries in all. A study with sites in several counts in each; 2 list no site.
Reported results
Completed studies with results posted on ClinicalTrials.gov, a results paper the registry links to the study, or both.
Completed pain and fatigue studies that name Verbal Learning: 19 of 39, 49%
Every completed study with a cognitive outcome: 3,626 of 7,953, 46%
| Results | Completed pain and fatigue studies that name Verbal Learning | Every completed study |
|---|---|---|
| Results on ClinicalTrials.gov and a paper | 4, 10% | 776, 10% |
| Results on ClinicalTrials.gov only | 8, 21% | 1,139, 14% |
| A results paper only | 7, 18% | 1,711, 22% |
| Neither | 20, 51% | 4,327, 54% |
The 72 studies
72 studies match. 16 name Verbal Learning in a primary outcome. Median size 90 participants. Median time to the primary outcome: 13 weeks.
Loading 72 studies; the filters turn on when they arrive.
2026 is partly planned starts. Not shown: 1 planned to start after 2026.
Show as a table
| Start year | Studies | As a primary outcome |
|---|---|---|
| 2000 | 0 | 0 |
| 2001 | 0 | 0 |
| 2002 | 0 | 0 |
| 2003 | 0 | 0 |
| 2004 | 2 | 1 |
| 2005 | 0 | 0 |
| 2006 | 1 | 0 |
| 2007 | 1 | 0 |
| 2008 | 1 | 1 |
| 2009 | 0 | 0 |
| 2010 | 1 | 0 |
| 2011 | 0 | 0 |
| 2012 | 1 | 0 |
| 2013 | 3 | 1 |
| 2014 | 4 | 1 |
| 2015 | 2 | 2 |
| 2016 | 8 | 0 |
| 2017 | 4 | 0 |
| 2018 | 2 | 1 |
| 2019 | 1 | 0 |
| 2020 | 3 | 1 |
| 2021 | 4 | 3 |
| 2022 | 4 | 0 |
| 2023 | 7 | 2 |
| 2024 | 11 | 2 |
| 2025 | 6 | 1 |
| 2026 | 5 | 0 |
Library tests named most
Largest condition groups
Phases
Participants
Lead sponsor: industry 5, other 67. Interventional 61, observational 11.
As a primary outcomeSecondary or other outcomeVerbal Learning
The studies, newest registration first
Each number opens the study's record on ClinicalTrials.gov.
| Study | Start | Phase | Conditions | Participants | Lead sponsor | Status | Library tests named, with the latest time point |
|---|---|---|---|---|---|---|---|
| NCT07886606 | Start2021 | PhaseEarly phase 1 | ConditionsSubstance use and addiction, Pain and fatigue | Participants34 | Lead sponsorOther | StatusRecruiting | Library tests named
|
| NCT07885085 | Start2027 | PhaseObservational | ConditionsMild cognitive impairment, Substance use and addiction, Delirium, surgery and intensive care, Pain and fatigue | Participants552 | Lead sponsorOther | StatusNot yet recruiting | Library tests named
|
| NCT07766213 | Start2026 | PhaseObservational | ConditionsMultiple sclerosis, Pain and fatigue | Participants60 | Lead sponsorOther | StatusRecruiting | Library tests named
|
| NCT07710742 | Start2026 | PhaseNot applicable | ConditionsMultiple sclerosis, Pain and fatigue | Participants51 | Lead sponsorOther | StatusNot yet recruiting | Library tests named
|
| NCT07680738 | Start2023 | PhaseNot applicable | ConditionsMultiple sclerosis, Pain and fatigue | Participants38 | Lead sponsorOther | StatusCompleted | Library tests named
|
| NCT07504120 | Start2025 | PhaseNot applicable | ConditionsMultiple sclerosis, Depression and bipolar disorder, Aging, frailty and exercise, Pain and fatigue | Participants50 | Lead sponsorOther | StatusRecruiting | Library tests named
|
| NCT07429526 | Start2013 | PhaseNot applicable | ConditionsStroke, Brain injury and concussion, Pain and fatigue | Participants12 | Lead sponsorOther | StatusCompleted | Library tests named
|
| NCT07409753 | Start2025 | PhasePhase 2 | ConditionsPain and fatigue | Participants60 | Lead sponsorOther | StatusRecruiting | Library tests named
|
| NCT07393672 | Start2026 | PhasePhase 2 | ConditionsAnxiety, PTSD and OCD, Pain and fatigue | Participants104 | Lead sponsorOther | StatusRecruiting | Library tests named
|
| NCT07357688 | Start2026 | PhaseNot applicable | ConditionsPain and fatigue | Participants99 | Lead sponsorOther | StatusNot yet recruiting | Library tests named
|
| NCT07304843 | Start2023 | PhasePhase 1/2 | ConditionsPain and fatigue | Participants207 | Lead sponsorIndustry | StatusCompleted | Library tests named
|
| NCT06837857 | Start2025 | PhasePhase 2 | ConditionsPain and fatigue | Participants200 | Lead sponsorOther | StatusRecruiting | Library tests named
|
| NCT06831916 | Start2025 | PhasePhase 2 | ConditionsAnxiety, PTSD and OCD, Pain and fatigue | Participants104 | Lead sponsorOther | StatusCompleted | Library tests named
|
| NCT06808048 | Start2025 | PhaseNot applicable | ConditionsSubstance use and addiction, Pain and fatigue | Participants180 | Lead sponsorOther | StatusRecruiting | Library tests named
|
| NCT06671132 | Start2024 | PhasePhase 2 | ConditionsPain and fatigue | Participants220 | Lead sponsorIndustry | StatusStatus unknown | Library tests named
|
| NCT06638996 | Start2024 | PhaseNot applicable | ConditionsAnxiety, PTSD and OCD, Pain and fatigue | Participants100 | Lead sponsorOther | StatusCompleted | Library tests named
|
| NCT06614309 | Start2024 | PhaseNot applicable | ConditionsCOVID-19 and long COVID, Pain and fatigue | Participants45 | Lead sponsorOther | StatusRecruiting | Library tests named
|
| NCT06569550 | Start2024 | PhaseNot applicable | ConditionsMultiple sclerosis, Pain and fatigue | Participants60 | Lead sponsorOther | StatusRecruiting | Library tests named
|
| NCT06544291 | Start2024 | PhasePhase 2 | ConditionsSubstance use and addiction, Pain and fatigue | Participants147 | Lead sponsorOther | StatusRecruiting | Library tests named
|
| NCT06530459 | Start2024 | PhasePhase 2/3 | ConditionsPain and fatigue | Participants100 | Lead sponsorOther | StatusRecruiting | Library tests named
|
| NCT06518421 | Start2024 | PhaseObservational | ConditionsPain and fatigue | Participants400 | Lead sponsorOther | StatusRecruiting | Library tests named
|
| NCT06448923 | Start2025 | PhasePhase 2 | ConditionsPain and fatigue | Participants225 | Lead sponsorOther | StatusRecruiting | Library tests named
|
| NCT06356805 | Start2023 | PhaseNot applicable | ConditionsAnxiety, PTSD and OCD, Pain and fatigue | Participants42 | Lead sponsorOther | StatusCompleted | Library tests named
|
| NCT06291870 | Start2023 | PhaseObservational | ConditionsSleep and sleep disorders, COVID-19 and long COVID, Pain and fatigue | Participants200 | Lead sponsorOther | StatusRecruiting | Library tests named
|
| NCT06290063 | Start2024 | PhasePhase 2 | ConditionsDepression and bipolar disorder, Sleep and sleep disorders, Anxiety, PTSD and OCD, Pain and fatigue | Participants385 | Lead sponsorOther | StatusRecruiting | Library tests named
|
Questions, answered from the data
How many pain and fatigue trials use Verbal Learning?
72 registered pain and fatigue studies on ClinicalTrials.gov name it in an outcome measure, 16 of them in a primary outcome: 11% of the condition's 681 studies with a cognitive outcome, against 11% of all of them. It is the 4th most named test in pain and fatigue trials.
Which tests do pain and fatigue trials use with Verbal Learning?
Symbol Coding (22 studies), the Trail Making Test (21 studies) and the Digit Span Test (19 studies).
How many participants do phase 2 pain and fatigue trials that use Verbal Learning enroll?
Half of the phase 2 studies that name it enroll 120 participants or fewer, and the middle half enroll 99 to 220. 17 of them give a size.
When do pain and fatigue trials measure Verbal Learning?
Half of the primary outcomes that name Verbal Learning are measured within 13 weeks of the start, and the middle half from 1 week to 4 months. 15 primary outcomes give a duration.
How many completed pain and fatigue trials that use Verbal Learning have reported results?
19 of the 39 completed studies that name it, 49%, have reported results: 12 posted them on ClinicalTrials.gov, 11 have a results paper linked to the registry record, and 4 did both. The other 20 show neither. Of all completed studies with a cognitive outcome, 46% have reported results.
How the studies are counted
For each test family, the census runs ClinicalTrials.gov's own outcome search for the family's names and reads every study first posted by the day the family was counted. These studies were read on 10 November 2026. A study counts once on a page, however many tests it names. Counts for a test cover every version of the task under any of its names, so a page can count studies that used a commercial version.
The census adds two things to each record and changes nothing in it: which outcome list names the test (primary, then secondary, then other), and the condition groups, matched on the study's condition names and MeSH terms. A study can fall in several groups; one whose only condition is cognitive impairment or decline falls in “Cognitive impairment and decline”. Studies that name only instruments outside the library count in every total and share but are not listed.
A second read on 10 November 2026 added each study's overall status, whether results are posted, its intervention types, the countries of its sites and the time frame of the outcome that names each test. A time frame counts by the latest time point it names: “Baseline, 12 and 24 weeks” is 24 weeks, a single visit is within a day, and one that names no duration, such as “end of treatment”, is left out of the timings.
A third read on 10 November 2026 added the papers the registry links to each study: those its sponsor lists as reporting results, and those PubMed links to it through the study's NCT number. A study has a results paper when one of them came out in or after the month of its primary completion and PubMed does not class it as a protocol, review or comment. A paper that never gives the NCT number is not linked, so some studies counted as reporting neither did publish.
Source: ClinicalTrials.gov, a database of the U.S. National Library of Medicine, which does not endorse these pages. Every study line is in the data release 2.1.0, and the explorer's own file is clinical-trials-studies.json.
The census counts Verbal Learning and Grocery Trip Game as one test family, so this page counts their studies together.
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