ConductCognition

  • Domains

    Tests

    • Processing speed43
    • Attention113
    • Working memory50
    • Executive function143
    • Episodic memory72
    • Response inhibition9
    • Social cognition75
    • Language42

    Most used

    Evidence

    1. Verbal Fluency TestGradeA
    2. Stroop Color-Word TestGradeA
    3. Trail Making TestGradeA
    4. N-Back TaskGradeA
    5. Go/No-Go TaskGradeA
    6. Digit Span TestGradeA
    7. Symbol Coding TestGradeA
    8. Verbal Learning TestGradeA
    REDTry it nowStroop Color-Word Test
    All 547 tests

    Browse by

    • Phone290
    • Tablet323
    • Untimed326
    • Up to 5 minutes69
    • Evidence grade A40

  • First studies

    Grade, length

    • Reaction Time StudyGradeA7 min
    • Pilot ScreeningGradeA15 min
    • Medication StudiesGradeA−26 min
    • Language-Minimized ScreeningGradeA−30 min

    Age groups

    • Older Adult Executive SpeedGradeA20 min
    • School-AgeGradeA−33 min

    Memory

    • At-Home MemoryGradeA26 min
    • Working Memory and LearningGradeA−19 min
    • Associative MemoryGradeB32 min
    • Working Memory CapacityGradeB34 min

    Language and perception

    • LanguageGradeA−33 min
    • Visual PerceptionGradeB27 min
    • Listening and Auditory ProcessingGradeB31 min

    Executive function and attention

    • Executive ControlGradeA18 min
    • Attention and ImpulsivityGradeA−26 min
    • Visual AttentionGradeB27 min
    • Creativity and Flexible ThinkingGradeB30 min
    • Reasoning and SpatialGradeB32 min

    Movement

    • Motor and AttentionGradeA−29 min
    • Motor LearningGradeB34 min

    Behavior, mood and choice

    • Food Choice and Self-ControlGradeA−29 min
    • Sleep and FatigueGradeB23 min
    • Social CognitionGradeB23 min
    • Impulsivity and Substance UseGradeB26 min
    • Emotion and MoodGradeB28 min
    • Decisions and RewardGradeB29 min
    All 26 batteries

    Find one

    Up to 15 minutes2Up to 30 minutes19Phone8
    Test order labBattery gradesHow batteries work

  • Use and evidence

    • Overview
    • Compare all 547 tests
    • Test-retest
    • Reliability and validity
    • Battery grades26
    • Download and cite

    Clinical trials

    • Overview
    • By condition25
    • By test101
    • Trial design benchmark
    • Cognitive outcomes, 2026

    Conditions

    Registered studies

    • Dementia and Alzheimer's1,673
    • Aging, frailty and exercise1,398
    • Depression and bipolar disorder1,247
    • Stroke1,233
    • Substance use and addiction895
    • Parkinson's disease892
    • Cancer760
    All 25 conditions
    16,361Registered studies name a cognitive test in an outcome measure11,688 name a test you can run hereExplore the studies
  • 1

    Build

    • Study design
    • Customize tests
    • Repeat visits
    • Study cost calculator
    2

    Recruit

    • Recruitment setup
    • Prolific
    • Sona Systems
    • CloudResearch Connect
    • Qualtrics
    3

    Run

    • Remote testing
    • Participant devices
    • Phone timing check
    • Offline edition
    4

    Results

    • Automated scoring
    • Test norms
    • Study Quality Monitor
    • Data export
    Platform overview

    Compliance

    • HIPAA-ready testing
    • US clinical research
    • Data Policy
    • Privacy Policy
    • Terms of Use

  • Research areas

    Tests used in each

    • Aging and dementia188
    • Decisions and reward105
    • Child development and education87
    • Language and bilingualism64
    • Social behavior62
    • Psychiatric groups35
    • Training and intervention28
    • Mood, anxiety and trauma25
    • Substance use and impulsivity25
    • Neurological and movement research19
    • Brain injury and concussion14
    • Sleep and fatigue14
    • ADHD11
    • Eating and obesity8
    • Medication and drug trials8

    Research settings

    • Student participant pools
    • Teaching a class
    • Clinical trials
    • US clinical research
    • Sites without internet
    Planning a study?

  • Methods

    • How evidence grades work
    • How test batteries work
    • How test order works
    Methods and questions

    Help

    • FAQ
    • Recruitment guides
    • Compare platforms

    Updates

    • Blog
    • New tests by email
    Latest post10 November 2026What you can do in ConductCognition todayA short tour of ConductCognition as it stands on 10 November. After this, we'll post when something changes how you run a study.Read the post
  • Pricing
Start Free
Log In
Log InStart Free
  1. Home
  2. /Data
  3. /Clinical trials
  4. /Conditions
  5. /Pain and fatigue

Clinical trials data

Cognitive tests in pain and fatigue trials: 681 registered studies

Every registered pain and fatigue study on ClinicalTrials.gov that names a cognitive test in an outcome measure: the tests used most, how often as a primary outcome, which tests go together, how large the studies are and when they measure the outcome.

Registered pain and fatigue studies name a cognitive test in an outcome
681
Name one in a primary outcome
237
See the tests
Median participants per study
60
By phase
Led by industry
53

The tests pain and fatigue trials use most

The Stroop Color-Word Test leads: 114 of the 681 studies name it, 17%. Next comes the Trail Making Test (94). As a primary outcome, the Stroop Color-Word Test leads with 43 studies.

  1. 1

    Stroop Color-Word Test114 studies, 43 as a primary outcome

  2. 2

    Trail Making Test94 studies, 27 as a primary outcome

  3. 3

    Symbol Coding82 studies, 17 as a primary outcome

  4. 4

    Verbal Learning72 studies, 16 as a primary outcome

  5. 5

    Digit Span Test61 studies, 29 as a primary outcome

  6. 6

    Verbal Fluency53 studies, 17 as a primary outcome

  7. 7

    Psychomotor Vigilance Task35 studies, 17 as a primary outcome

  8. 8

    N-Back Task31 studies, 12 as a primary outcome

  9. 9

    Paced Visual Serial Addition Test28 studies, 13 as a primary outcome

  10. 10

    Continuous Performance Test27 studies, 10 as a primary outcome

  11. 11

    Simple Reaction Time22 studies, 11 as a primary outcome

  12. 12

    Go/No-Go Task22 studies, 8 as a primary outcome

  13. 13

    Rapid Visual Information Processing18 studies, 9 as a primary outcome

  14. 14

    Category Fluency16 studies, 5 as a primary outcome

  15. 15

    Paired Associate Learning14 studies, 3 as a primary outcome

  16. 16

    Choice Reaction Time13 studies, 7 as a primary outcome

  17. 17

    Task Switching Test13 studies, 2 as a primary outcome

  18. 18

    Eriksen Flanker Task12 studies, 7 as a primary outcome

  19. 19

    Attention Network Test12 studies, 3 as a primary outcome

  20. 20

    Tower Planning11 studies, 5 as a primary outcome

  21. 21

    Card Sorting Test (Berg)11 studies, 3 as a primary outcome

  22. 22

    Corsi Block-Tapping Test10 studies, 7 as a primary outcome

  23. 23

    Stop-Signal Task9 studies, 4 as a primary outcome

  24. 24

    Matrix Reasoning9 studies, 3 as a primary outcome

  25. 25

    Finger Tapping Task8 studies, 2 as a primary outcome

A test as a primary outcomeOnly in secondary or other outcomes

23% of pain and fatigue studies name only instruments outside the library, such as clinician-administered screening scales. They count in every figure on this page and are not listed. The explorer below holds all 98 tests.

Tests used together

The pairs of tests pain and fatigue studies name together most often.
  1. Stroop Color-Word Test and Trail Making Test26 studies name both
  2. Digit Span Test and Trail Making Test25 studies name both
  3. Symbol Coding and Verbal Learning22 studies name both
  4. Trail Making Test and Verbal Learning21 studies name both
  5. Digit Span Test and Verbal Fluency19 studies name both
  6. Digit Span Test and Verbal Learning19 studies name both
  7. Trail Making Test and Verbal Fluency18 studies name both
  8. Verbal Fluency and Verbal Learning16 studies name both
  9. Stroop Color-Word Test and Verbal Fluency13 studies name both
  10. Symbol Coding and Trail Making Test13 studies name both

Studies by start year

Each study counted once. 2026 is partly planned starts.
02000: 1 studies, 0 with a test as a primary outcome20002001: 0 studies, 0 with a test as a primary outcome2002: 3 studies, 0 with a test as a primary outcome2003: 0 studies, 0 with a test as a primary outcome2004: 3 studies, 2 with a test as a primary outcome2005: 1 studies, 0 with a test as a primary outcome20052006: 4 studies, 2 with a test as a primary outcome2007: 6 studies, 2 with a test as a primary outcome2008: 7 studies, 4 with a test as a primary outcome2009: 6 studies, 2 with a test as a primary outcome2010: 7 studies, 2 with a test as a primary outcome20102011: 9 studies, 3 with a test as a primary outcome2012: 11 studies, 4 with a test as a primary outcome2013: 16 studies, 5 with a test as a primary outcome2014: 14 studies, 5 with a test as a primary outcome2015: 13 studies, 7 with a test as a primary outcome20152016: 27 studies, 6 with a test as a primary outcome2017: 33 studies, 6 with a test as a primary outcome2018: 37 studies, 11 with a test as a primary outcome2019: 37 studies, 12 with a test as a primary outcome2020: 32 studies, 11 with a test as a primary outcome20202021: 60 studies, 29 with a test as a primary outcome2022: 48 studies, 15 with a test as a primary outcome2023: 69 studies, 23 with a test as a primary outcome2024: 78 studies, 34 with a test as a primary outcome2025: 81 studies, 26 with a test as a primary outcome20252026: 74 studies, 26 with a test as a primary outcome

A test as a primary outcomeOnly in secondary or other outcomes

Show as a table
Registered studies by start year
Start yearStudiesA test as a primary outcome
200010
200100
200230
200300
200432
200510
200642
200762
200874
200962
201072
201193
2012114
2013165
2014145
2015137
2016276
2017336
20183711
20193712
20203211
20216029
20224815
20236923
20247834
20258126
20267426

Phases and sponsors

By phase

  • Early phase 114 studies, 8 as a primary outcome
  • Phase 117 studies, 7 as a primary outcome
  • Phase 1/210 studies, 0 as a primary outcome
  • Phase 257 studies, 11 as a primary outcome
  • Phase 2/312 studies, 2 as a primary outcome
  • Phase 329 studies, 7 as a primary outcome
  • Phase 426 studies, 7 as a primary outcome
  • Not applicable399 studies, 142 as a primary outcome
  • Observational117 studies, 53 as a primary outcome

Sponsors and study types

Lead sponsor: industry 53, NIH 2, universities, hospitals and others 626. Interventional 564, observational 117.

Status, results, interventions and countries

Status

  • Recruiting126 studies, 35 as a primary outcome
  • Not yet recruiting46 studies, 13 as a primary outcome
  • Active, not recruiting16 studies, 3 as a primary outcome
  • Completed357 studies, 126 as a primary outcome
  • Stopped early37 studies, 19 as a primary outcome
  • Status unknown99 studies, 41 as a primary outcome

What they test

  • Behavioral157 studies, 50 as a primary outcome
  • Drug179 studies, 47 as a primary outcome
  • Device127 studies, 44 as a primary outcome
  • Dietary supplement45 studies, 23 as a primary outcome
  • Procedure21 studies, 6 as a primary outcome
  • Diagnostic test18 studies, 9 as a primary outcome
  • Biological3 studies, 2 as a primary outcome
  • Radiation3 studies, 1 as a primary outcome
  • Combination product2 studies, 0 as a primary outcome
  • Other181 studies, 67 as a primary outcome
  • None given49 studies, 22 as a primary outcome

Intervention types as registered. A study can list several; observational studies often list none.

Where their sites are

  • United States216 studies, 81 as a primary outcome
  • Türkiye62 studies, 26 as a primary outcome
  • Canada35 studies, 11 as a primary outcome
  • Spain31 studies, 7 as a primary outcome
  • United Kingdom29 studies, 12 as a primary outcome
  • France28 studies, 6 as a primary outcome
  • China27 studies, 7 as a primary outcome
  • Italy24 studies, 9 as a primary outcome
  • Belgium23 studies, 10 as a primary outcome
  • Denmark21 studies, 4 as a primary outcome
  • Germany18 studies, 6 as a primary outcome
  • Norway18 studies, 1 as a primary outcome

50 countries in all. A study with sites in several counts in each; 46 list no site.

Reported results

Completed studies with results posted on ClinicalTrials.gov, a results paper the registry links to the study, or both.

Completed pain and fatigue studies: 149 of 357, 42%

Every completed study with a cognitive outcome: 3,626 of 7,953, 46%

Completed pain and fatigue studies and every completed study, by how they reported results
ResultsCompleted pain and fatigue studiesEvery completed study
Results on ClinicalTrials.gov and a paper27, 8%776, 10%
Results on ClinicalTrials.gov only42, 12%1,139, 14%
A results paper only80, 22%1,711, 22%
Neither208, 58%4,327, 54%

How many participants they enroll

Enrollment as registered: actual for a finished study, planned for one still recruiting.
102050100200
  • Early phase 136 median, 28 to 60
  • Phase 132 median, 20 to 76
  • Phase 1/233 median, 15 to 56
  • Phase 2100 median, 49 to 148
  • Phase 2/371 median, 40 to 105
  • Phase 372 median, 44 to 157
  • Phase 4102 median, 30 to 254
  • Not applicable59 median, 30 to 100
  • Observational93 median, 50 to 183
Participants per study. The bar spans the middle half of the studies in each phase, the mark is the median, and the axis is logarithmic. Phases with fewer than 10 studies that give a size are left out.
Show as a table
Participants per pain and fatigue study by phase
PhaseStudies with a sizeMedianMiddle half
Early phase 1133628 to 60
Phase 1173220 to 76
Phase 1/2103315 to 56
Phase 25510049 to 148
Phase 2/3127140 to 105
Phase 3297244 to 157
Phase 42510230 to 254
Not applicable3935930 to 100
Observational1159350 to 183

When the cognitive outcome is measured

Half of the primary outcomes that name a library test are measured within 5 weeks of the start, and the middle half from the first day to 12 weeks. 306 primary outcomes give a duration.

Latest time point of each outcome

  • Within a day184 outcomes, 80 as a primary outcome
  • Up to 4 weeks200 outcomes, 72 as a primary outcome
  • 1 to 3 months290 outcomes, 93 as a primary outcome
  • 3 to 6 months95 outcomes, 27 as a primary outcome
  • 6 to 12 months79 outcomes, 16 as a primary outcome
  • 1 to 2 years28 outcomes, 14 as a primary outcome
  • Over 2 years12 outcomes, 4 as a primary outcome
  • No duration given95 outcomes, 44 as a primary outcome

A test as a primary outcomeOnly in secondary or other outcomes

888 of the 983 outcome measures give a duration. A single visit counts as within a day.

Median time to the primary outcome, by test

Median weeks to the latest time point of each test's primary outcomes
TestPrimary outcomesMedian
Stroop Color-Word Test342 weeks
Digit Span Test258 weeks
Trail Making Test249 weeks
Psychomotor Vigilance Task163 weeks
Verbal Fluency1610 weeks
Symbol Coding159 weeks
Verbal Learning1513 weeks
Simple Reaction Time113 weeks
Continuous Performance Test106 weeks
Paced Visual Serial Addition Test1013 weeks

Explore the pain and fatigue studies

The 521 pain and fatigue studies that name a test in the library, with filters for test, phase, sponsor, status, country, intervention, outcome list, size and start year. Each study links to its record on ClinicalTrials.gov.
ConditionPain and fatigue

521 studies match. 196 name a library test in a primary outcome. Median size 60 participants. Median time to the primary outcome: 5 weeks.

Loading 521 studies; the filters turn on when they arrive.

By start year
02040602000: 1 studies, 0 naming a library test in a primary outcome20002001: 0 studies, 0 naming a library test in a primary outcome2002: 3 studies, 0 naming a library test in a primary outcome2003: 0 studies, 0 naming a library test in a primary outcome2004: 3 studies, 2 naming a library test in a primary outcome2005: 1 studies, 0 naming a library test in a primary outcome20052006: 4 studies, 2 naming a library test in a primary outcome2007: 6 studies, 2 naming a library test in a primary outcome2008: 7 studies, 4 naming a library test in a primary outcome2009: 5 studies, 2 naming a library test in a primary outcome2010: 7 studies, 2 naming a library test in a primary outcome20102011: 8 studies, 3 naming a library test in a primary outcome2012: 10 studies, 4 naming a library test in a primary outcome2013: 16 studies, 5 naming a library test in a primary outcome2014: 12 studies, 5 naming a library test in a primary outcome2015: 12 studies, 7 naming a library test in a primary outcome20152016: 22 studies, 6 naming a library test in a primary outcome2017: 25 studies, 5 naming a library test in a primary outcome2018: 25 studies, 9 naming a library test in a primary outcome2019: 22 studies, 7 naming a library test in a primary outcome2020: 25 studies, 10 naming a library test in a primary outcome20202021: 46 studies, 25 naming a library test in a primary outcome2022: 38 studies, 13 naming a library test in a primary outcome2023: 45 studies, 17 naming a library test in a primary outcome2024: 58 studies, 28 naming a library test in a primary outcome2025: 58 studies, 18 naming a library test in a primary outcome20252026: 58 studies, 20 naming a library test in a primary outcome

2026 is partly planned starts. Not shown: 4 planned to start after 2026.

Show as a table
Matching studies by start year
Start yearStudiesAs a primary outcome
200010
200100
200230
200300
200432
200510
200642
200762
200874
200952
201072
201183
2012104
2013165
2014125
2015127
2016226
2017255
2018259
2019227
20202510
20214625
20223813
20234517
20245828
20255818
20265820

Library tests named most

Largest condition groups

  • Pain and fatigue521 studies, 196 as a primary outcome
  • Sleep and sleep disorders53 studies, 23 as a primary outcome
  • Multiple sclerosis49 studies, 16 as a primary outcome
  • Depression and bipolar disorder46 studies, 19 as a primary outcome
  • Anxiety, PTSD and OCD45 studies, 20 as a primary outcome
  • Cancer36 studies, 10 as a primary outcome
  • Substance use and addiction34 studies, 14 as a primary outcome
  • COVID-19 and long COVID32 studies, 12 as a primary outcome
  • Delirium, surgery and intensive care27 studies, 7 as a primary outcome
  • Aging, frailty and exercise26 studies, 8 as a primary outcome
  • Cardiovascular disease16 studies, 10 as a primary outcome
  • Healthy volunteers15 studies, 9 as a primary outcome

Phases

Participants

Lead sponsor: industry 48, NIH 2, other 471. Interventional 450, observational 71.

As a primary outcomeSecondary or other outcome

The studies, newest registration first

Each number opens the study's record on ClinicalTrials.gov.

Registered studies that match the filters, newest registration first, with the library tests each one names and the outcome list that names them.
StudyStartPhaseConditionsParticipantsLead sponsorStatusLibrary tests named, with the latest time point
NCT07906847Start2026PhaseObservationalConditionsPain and fatigueParticipants80Lead sponsorOtherStatusNot yet recruitingLibrary tests named
  • Trail Making TestPrimary
  • Stroop Color-Word TestPrimary
  • Digit Span TestPrimary
NCT07898722Start2025PhaseNot applicableConditionsAnxiety, PTSD and OCD, Pain and fatigueParticipants40Lead sponsorOtherStatusCompletedLibrary tests named
  • Symbol CodingSecondary
NCT07894965Start2026PhaseNot applicableConditionsPain and fatigueParticipants90Lead sponsorOtherStatusNot yet recruitingLibrary tests named
  • Arithmetic Fluency TaskSecondary12 weeks
NCT07889466Start2025PhaseNot applicableConditionsSleep and sleep disorders, Pain and fatigueParticipants203Lead sponsorOtherStatusCompletedLibrary tests named
  • Psychomotor Vigilance TaskPrimary6 weeks
NCT07886606Start2021PhaseEarly phase 1ConditionsSubstance use and addiction, Pain and fatigueParticipants34Lead sponsorOtherStatusRecruitingLibrary tests named
  • Verbal LearningPrimarysame day
  • Continuous Performance TestPrimarysame day
NCT07885085Start2027PhaseObservationalConditionsMild cognitive impairment, Substance use and addiction, Delirium, surgery and intensive care, Pain and fatigueParticipants552Lead sponsorOtherStatusNot yet recruitingLibrary tests named
  • Verbal LearningOther outcome6 months
NCT07867041Start2024PhaseNot applicableConditionsPain and fatigueParticipants24Lead sponsorOtherStatusCompletedLibrary tests named
  • Stroop Color-Word TestPrimary1 week
NCT07852156Start2026PhaseNot applicableConditionsMultiple sclerosis, Pain and fatigueParticipants42Lead sponsorOtherStatusRecruitingLibrary tests named
  • Symbol CodingSecondary2 weeks
NCT07851896Start2026PhaseNot applicableConditionsPain and fatigueParticipants40Lead sponsorOtherStatusNot yet recruitingLibrary tests named
  • Trail Making TestSecondary12 weeks
  • Stroop Color-Word TestSecondary12 weeks
NCT07843108Start2026PhasePhase 1/2ConditionsPain and fatigueParticipants8Lead sponsorIndustryStatusActive, not recruitingLibrary tests named
  • Finger Tapping TaskSecondary4 months
NCT07842302Start2026PhaseNot applicableConditionsMultiple sclerosis, Pain and fatigueParticipants80Lead sponsorOtherStatusNot yet recruitingLibrary tests named
  • Trail Making TestSecondary6 months
  • Stroop Color-Word TestSecondary6 months
  • Verbal FluencySecondary6 months
  • Symbol CodingPrimary6 months
  • Paced Visual Serial Addition TestSecondary6 months
  • Selective Reminding TaskSecondary6 months
NCT07820475Start2026PhaseObservationalConditionsPain and fatigueParticipants400Lead sponsorOtherStatusNot yet recruitingLibrary tests named
  • Spatial Working MemorySecondary3 weeks
NCT07802860Start2026PhaseNot applicableConditionsPain and fatigueParticipants30Lead sponsorOtherStatusNot yet recruitingLibrary tests named
  • N-Back TaskSecondary6 months
NCT07792850Start2027PhaseNot applicableConditionsPain and fatigueParticipants625Lead sponsorOtherStatusNot yet recruitingLibrary tests named
  • Category FluencySecondary11 months
NCT07791355Start2026PhaseNot applicableConditionsPain and fatigueParticipants25Lead sponsorOtherStatusRecruitingLibrary tests named
  • Stroop Color-Word TestOther outcome9 weeks
  • Go/No-Go TaskOther outcome9 weeks
  • Recognition Memory TestOther outcome9 weeks
NCT07786987Start2026PhaseObservationalConditionsMultiple sclerosis, Pain and fatigueParticipants50Lead sponsorOtherStatusNot yet recruitingLibrary tests named
  • Symbol CodingSecondarysame day
NCT07783074Start2026PhaseObservationalConditionsMultiple sclerosis, Healthy volunteers, COVID-19 and long COVID, Pain and fatigueParticipants122Lead sponsorOtherStatusRecruitingLibrary tests named
  • Symbol CodingSecondary9 weeks
  • Finger Tapping TaskPrimary9 weeks
NCT07779304Start2026PhaseNot applicableConditionsPain and fatigueParticipants32Lead sponsorOtherStatusNot yet recruitingLibrary tests named
  • Stroop Color-Word TestSecondarysame day
NCT07766980Start2026PhasePhase 2ConditionsPain and fatigueParticipants20Lead sponsorOtherStatusRecruitingLibrary tests named
  • Trail Making TestSecondary10 weeks
  • Verbal FluencySecondary10 weeks
NCT07766213Start2026PhaseObservationalConditionsMultiple sclerosis, Pain and fatigueParticipants60Lead sponsorOtherStatusRecruitingLibrary tests named
  • Verbal LearningSecondarysame day
  • Symbol CodingSecondarysame day
NCT07761611Start2026PhaseNot applicableConditionsPain and fatigueParticipants118Lead sponsorOtherStatusNot yet recruitingLibrary tests named
  • Psychomotor Vigilance TaskPrimary3 weeks
  • Simple Reaction TimePrimary3 weeks
NCT07755475Start2025PhaseNot applicableConditionsPain and fatigueParticipants50Lead sponsorIndustryStatusCompletedLibrary tests named
  • Digit Span TestPrimary4 weeks
NCT07752329Start2026PhaseNot applicableConditionsPain and fatigueParticipants70Lead sponsorOtherStatusNot yet recruitingLibrary tests named
  • Stroop Color-Word TestSecondary6 weeks
  • Choice Reaction TimePrimary6 weeks
  • Simple Reaction TimePrimary6 weeks
  • Rapid Visual Information ProcessingSecondary6 weeks
  • Delayed Recall ModuleSecondary6 weeks
  • Finger Tapping TaskSecondary6 weeks
  • Fitts Pointing TaskSecondary6 weeks
  • Multiple Object TrackingSecondary6 weeks
NCT07742605Start2025PhaseNot applicableConditionsPain and fatigueParticipants35Lead sponsorIndustryStatusCompletedLibrary tests named
  • Digit Span TestPrimary6 weeks
NCT07740967Start2026PhaseNot applicableConditionsSleep and sleep disorders, Pain and fatigue, Cardiovascular diseaseParticipants34Lead sponsorOtherStatusRecruitingLibrary tests named
  • Stroop Color-Word TestSecondary8 weeks
  • Digit Span TestSecondary8 weeks
  • Pattern and Letter ComparisonSecondary8 weeks

Page 1 of 21

Questions, answered from the data

Which cognitive test do pain and fatigue trials use most?

The Stroop Color-Word Test: 114 of the 681 registered studies name it in an outcome measure, 17%. Next come the Trail Making Test (94) and Symbol Coding (82).

Which cognitive test do pain and fatigue trials use most as a primary outcome?

The Stroop Color-Word Test, named in a primary outcome by 43 studies. 237 of the 681 studies, 35%, name a cognitive test in a primary outcome.

How many participants does a phase 2 pain and fatigue trial enroll?

Half of the phase 2 pain and fatigue studies enroll 100 participants or fewer, and the middle half enroll 49 to 148. 55 of them give a size.

How long after the start do pain and fatigue trials measure a cognitive outcome?

Half of the primary outcomes that name a library test are measured within 5 weeks of the start, and the middle half from the first day to 12 weeks. 306 primary outcomes give a duration.

Which cognitive tests do pain and fatigue trials use together?

The Stroop Color-Word Test with the Trail Making Test most often: 26 studies name both. Next, the Digit Span Test with the Trail Making Test (25).

How many completed pain and fatigue trials have reported results?

149 of the 357 completed pain and fatigue studies, 42%, have reported results: 69 posted them on ClinicalTrials.gov, 107 have a results paper linked to the registry record, and 27 did both. The other 208 show neither. Of all completed studies with a cognitive outcome, 46% have reported results.

Other conditions

  • Sleep and sleep disorders62 shared
  • Depression and bipolar disorder58 shared
  • Anxiety, PTSD and OCD57 shared
  • Delirium, surgery and intensive care57 shared
  • Multiple sclerosis54 shared
  • Cancer46 shared
  • COVID-19 and long COVID46 shared
  • Aging, frailty and exercise41 shared
  • Substance use and addiction35 shared
  • Cardiovascular disease21 shared
  • Brain injury and concussion21 shared
  • Stroke20 shared
  • Healthy volunteers15 shared
  • Parkinson's disease13 shared
  • Dementia and Alzheimer's11 shared
  • Obesity and diabetes10 shared
  • Mild cognitive impairment6 shared
  • Lung disease3 shared
  • Schizophrenia and psychosis2 shared
  • ADHD1 shared
  • Hearing loss1 shared
  • Cognitive impairment and decline354 studies
  • Autism200 studies
  • Epilepsy138 studies

All 16,361 registered studies, by test, condition, phase and year.

How the studies are counted

For each test family, the census runs ClinicalTrials.gov's own outcome search for the family's names and reads every study first posted by the day the family was counted. These studies were read on 10 November 2026. A study counts once on a page, however many tests it names. Counts for a test cover every version of the task under any of its names, so a page can count studies that used a commercial version.

The census adds two things to each record and changes nothing in it: which outcome list names the test (primary, then secondary, then other), and the condition groups, matched on the study's condition names and MeSH terms. A study can fall in several groups; one whose only condition is cognitive impairment or decline falls in “Cognitive impairment and decline”. Studies that name only instruments outside the library count in every total and share but are not listed.

A second read on 10 November 2026 added each study's overall status, whether results are posted, its intervention types, the countries of its sites and the time frame of the outcome that names each test. A time frame counts by the latest time point it names: “Baseline, 12 and 24 weeks” is 24 weeks, a single visit is within a day, and one that names no duration, such as “end of treatment”, is left out of the timings.

A third read on 10 November 2026 added the papers the registry links to each study: those its sponsor lists as reporting results, and those PubMed links to it through the study's NCT number. A study has a results paper when one of them came out in or after the month of its primary completion and PubMed does not class it as a protocol, review or comment. A paper that never gives the NCT number is not linked, so some studies counted as reporting neither did publish.

Source: ClinicalTrials.gov, a database of the U.S. National Library of Medicine, which does not endorse these pages. Every study line is in the data release 2.1.0, and the explorer's own file is clinical-trials-studies.json.

Plan the cognitive outcomes of a pain and fatigue trial

Choose tests with a record in registered trials, and run them in a browser at every site, on the same version each visit.

Start free
ConductCognition

Hosted browser-native cognitive testing for academic and commercial research workflows.

A product of ConductScience, Inc.

New tests and features, about once a month. Unsubscribe at any time.

Tests

  • All cognitive tests
  • Test batteries
  • Use and evidence
  • Test norms
  • Trail Making Test
  • N-Back Task
  • Automated scoring
  • Study design
  • New tests by email

Guides

  • Methods and questions
  • Blog
  • Recruitment setup
  • Participant devices
  • Prolific
  • Sona Systems
  • CloudResearch Connect
  • Qualtrics

Use cases

  • Student participant pools
  • Aging and dementia research
  • Clinical trials
  • US clinical research
  • Remote testing

Compare and buy

  • Pricing
  • Compare platforms
  • Offline edition
  • FAQ

Trust

  • Study Quality Monitor
  • HIPAA-ready testing
  • Data export
  • Privacy Policy
  • Terms of Use
  • Data Policy

Company

  • ConductScience
  • Affiliate Program
© 2026 ConductScience, Inc. Research use only.