Clinical trials data
Verbal Fluency in depression and bipolar disorder trials: 154 registered studies
Every registered depression and bipolar disorder study on ClinicalTrials.gov that names Verbal Fluency in an outcome measure: how often it is a primary outcome, the tests named with it, how large the studies are and when they measure it.
- Registered depression and bipolar disorder studies name it in an outcome measure
- 154
- Name it in a primary outcome, 28%
- 43 of 154
Tests named in the same studies
- 1
Trail Making Test57 studies, 20 as a primary outcome
- 2
Verbal Learning56 studies, 19 as a primary outcome
- 3
Digit Span Test56 studies, 14 as a primary outcome
- 4
Stroop Color-Word Test35 studies, 11 as a primary outcome
- 5
Symbol Coding24 studies, 8 as a primary outcome
- 6
Category Fluency23 studies, 7 as a primary outcome
- 7
N-Back Task13 studies, 4 as a primary outcome
- 8
Picture Naming Test11 studies, 1 as a primary outcome
- 9
Continuous Performance Test10 studies, 7 as a primary outcome
- 10
Card Sorting Test (Berg)10 studies, 3 as a primary outcome
A test as a primary outcomeOnly in secondary or other outcomes
Studies by start year
A test as a primary outcomeOnly in secondary or other outcomes
Show as a table
| Start year | Studies | A test as a primary outcome |
|---|---|---|
| 2000 | 0 | 0 |
| 2001 | 0 | 0 |
| 2002 | 0 | 0 |
| 2003 | 0 | 0 |
| 2004 | 1 | 0 |
| 2005 | 3 | 1 |
| 2006 | 1 | 0 |
| 2007 | 1 | 0 |
| 2008 | 0 | 0 |
| 2009 | 1 | 0 |
| 2010 | 4 | 0 |
| 2011 | 2 | 0 |
| 2012 | 1 | 0 |
| 2013 | 6 | 0 |
| 2014 | 2 | 0 |
| 2015 | 7 | 4 |
| 2016 | 7 | 3 |
| 2017 | 8 | 4 |
| 2018 | 4 | 0 |
| 2019 | 10 | 4 |
| 2020 | 6 | 3 |
| 2021 | 15 | 6 |
| 2022 | 10 | 0 |
| 2023 | 19 | 5 |
| 2024 | 16 | 4 |
| 2025 | 18 | 3 |
| 2026 | 10 | 5 |
Phases and study sizes
By phase
- Early phase 13 studies, 0 as a primary outcome
- Phase 13 studies, 1 as a primary outcome
- Phase 1/26 studies, 1 as a primary outcome
- Phase 214 studies, 5 as a primary outcome
- Phase 2/31 studies, 0 as a primary outcome
- Phase 37 studies, 0 as a primary outcome
- Phase 47 studies, 2 as a primary outcome
- Not applicable91 studies, 24 as a primary outcome
- Observational22 studies, 10 as a primary outcome
Participants per study
- Phase 260 median, 39 to 84
- Not applicable66 median, 45 to 120
- Observational112 median, 81 to 192
Show as a table
| Phase | Studies with a size | Median | Middle half |
|---|---|---|---|
| Phase 2 | 14 | 60 | 39 to 84 |
| Not applicable | 89 | 66 | 45 to 120 |
| Observational | 22 | 112 | 81 to 192 |
When depression and bipolar disorder trials measure it
Latest time point of each outcome
- Within a day11 outcomes, 4 as a primary outcome
- Up to 4 weeks30 outcomes, 8 as a primary outcome
- 1 to 3 months60 outcomes, 19 as a primary outcome
- 3 to 6 months17 outcomes, 4 as a primary outcome
- 6 to 12 months14 outcomes, 0 as a primary outcome
- 1 to 2 years6 outcomes, 2 as a primary outcome
- Over 2 years3 outcomes, 0 as a primary outcome
- No duration given13 outcomes, 6 as a primary outcome
A test as a primary outcomeOnly in secondary or other outcomes
141 of the 154 outcome measures give a duration. A single visit counts as within a day.
Status, results, interventions and countries
Status
- Recruiting33 studies, 10 as a primary outcome
- Not yet recruiting9 studies, 2 as a primary outcome
- Active, not recruiting12 studies, 2 as a primary outcome
- Completed60 studies, 23 as a primary outcome
- Stopped early16 studies, 2 as a primary outcome
- Status unknown24 studies, 4 as a primary outcome
What they test
- Behavioral45 studies, 13 as a primary outcome
- Drug38 studies, 9 as a primary outcome
- Device41 studies, 8 as a primary outcome
- Dietary supplement4 studies, 3 as a primary outcome
- Procedure9 studies, 2 as a primary outcome
- Diagnostic test4 studies, 1 as a primary outcome
- Biological2 studies, 0 as a primary outcome
- Radiation2 studies, 1 as a primary outcome
- Combination product2 studies, 0 as a primary outcome
- Other30 studies, 9 as a primary outcome
- None given10 studies, 5 as a primary outcome
Intervention types as registered. A study can list several; observational studies often list none.
Where their sites are
- United States42 studies, 9 as a primary outcome
- Denmark16 studies, 8 as a primary outcome
- Canada15 studies, 2 as a primary outcome
- France12 studies, 1 as a primary outcome
- China9 studies, 3 as a primary outcome
- Brazil8 studies, 2 as a primary outcome
- Netherlands6 studies, 2 as a primary outcome
- Germany4 studies, 0 as a primary outcome
- Hong Kong4 studies, 3 as a primary outcome
- Spain4 studies, 2 as a primary outcome
- Argentina3 studies, 2 as a primary outcome
- Australia3 studies, 0 as a primary outcome
33 countries in all. A study with sites in several counts in each; 6 list no site.
Reported results
Completed studies with results posted on ClinicalTrials.gov, a results paper the registry links to the study, or both.
Completed depression and bipolar disorder studies that name Verbal Fluency: 32 of 60, 53%
Every completed study with a cognitive outcome: 3,626 of 7,953, 46%
| Results | Completed depression and bipolar disorder studies that name Verbal Fluency | Every completed study |
|---|---|---|
| Results on ClinicalTrials.gov and a paper | 8, 13% | 776, 10% |
| Results on ClinicalTrials.gov only | 5, 8% | 1,139, 14% |
| A results paper only | 19, 32% | 1,711, 22% |
| Neither | 28, 47% | 4,327, 54% |
The 154 studies
154 studies match. 43 name Verbal Fluency in a primary outcome. Median size 70 participants. Median time to the primary outcome: 8 weeks.
Loading 154 studies; the filters turn on when they arrive.
2026 is partly planned starts. Not shown: 2 that started before 2000.
Show as a table
| Start year | Studies | As a primary outcome |
|---|---|---|
| 2000 | 0 | 0 |
| 2001 | 0 | 0 |
| 2002 | 0 | 0 |
| 2003 | 0 | 0 |
| 2004 | 1 | 0 |
| 2005 | 3 | 1 |
| 2006 | 1 | 0 |
| 2007 | 1 | 0 |
| 2008 | 0 | 0 |
| 2009 | 1 | 0 |
| 2010 | 4 | 0 |
| 2011 | 2 | 0 |
| 2012 | 1 | 0 |
| 2013 | 6 | 0 |
| 2014 | 2 | 0 |
| 2015 | 7 | 4 |
| 2016 | 7 | 3 |
| 2017 | 8 | 4 |
| 2018 | 4 | 0 |
| 2019 | 10 | 4 |
| 2020 | 6 | 3 |
| 2021 | 15 | 6 |
| 2022 | 10 | 0 |
| 2023 | 19 | 5 |
| 2024 | 16 | 4 |
| 2025 | 18 | 3 |
| 2026 | 10 | 5 |
Library tests named most
Largest condition groups
Phases
Participants
Lead sponsor: industry 6, other 148. Interventional 132, observational 22.
As a primary outcomeSecondary or other outcomeVerbal Fluency
The studies, newest registration first
Each number opens the study's record on ClinicalTrials.gov.
| Study | Start | Phase | Conditions | Participants | Lead sponsor | Status | Library tests named, with the latest time point |
|---|---|---|---|---|---|---|---|
| NCT07857122 | Start2026 | PhaseNot applicable | ConditionsDepression and bipolar disorder | Participants108 | Lead sponsorOther | StatusNot yet recruiting | Library tests named
|
| NCT07755839 | Start2026 | PhaseNot applicable | ConditionsDepression and bipolar disorder, Cancer, Anxiety, PTSD and OCD | Participants60 | Lead sponsorOther | StatusNot yet recruiting | Library tests named
|
| NCT07664852 | Start2026 | PhasePhase 3 | ConditionsDepression and bipolar disorder | Participants126 | Lead sponsorOther | StatusRecruiting | Library tests named
|
| NCT07633626 | Start2026 | PhaseObservational | ConditionsDepression and bipolar disorder, Cancer | Participants24 | Lead sponsorOther | StatusRecruiting | Library tests named
|
| NCT07619092 | Start2026 | PhaseNot applicable | ConditionsDepression and bipolar disorder | Participants145 | Lead sponsorOther | StatusRecruiting | Library tests named
|
| NCT07593807 | Start2025 | PhaseNot applicable | ConditionsMultiple sclerosis, Depression and bipolar disorder | Participants30 | Lead sponsorOther | StatusActive, not recruiting | Library tests named
|
| NCT07561307 | Start2026 | PhaseNot applicable | ConditionsDepression and bipolar disorder | Participants64 | Lead sponsorOther | StatusNot yet recruiting | Library tests named
|
| NCT07533773 | Start2026 | PhaseNot applicable | ConditionsDepression and bipolar disorder | Participants60 | Lead sponsorOther | StatusRecruiting | Library tests named
|
| NCT07506070 | Start2026 | PhaseNot applicable | ConditionsSchizophrenia and psychosis, Depression and bipolar disorder, Autism, Anxiety, PTSD and OCD | Participants160 | Lead sponsorOther | StatusNot yet recruiting | Library tests named
|
| NCT07404085 | Start2025 | PhaseNot applicable | ConditionsSchizophrenia and psychosis, Depression and bipolar disorder | Participants160 | Lead sponsorOther | StatusRecruiting | Library tests named
|
| NCT07402356 | Start2025 | PhaseObservational | ConditionsDementia and Alzheimer's, Mild cognitive impairment, Depression and bipolar disorder | Participants140 | Lead sponsorOther | StatusRecruiting | Library tests named
|
| NCT07350226 | Start2025 | PhaseNot applicable | ConditionsDepression and bipolar disorder | Participants86 | Lead sponsorOther | StatusActive, not recruiting | Library tests named
|
| NCT07309302 | Start2025 | PhaseNot applicable | ConditionsDepression and bipolar disorder, Anxiety, PTSD and OCD | Participants64 | Lead sponsorOther | StatusRecruiting | Library tests named
|
| NCT07294924 | Start2026 | PhaseObservational | ConditionsDepression and bipolar disorder | Participants11 | Lead sponsorIndustry | StatusStopped early | Library tests named
|
| NCT07273604 | Start2015 | PhaseNot applicable | ConditionsMultiple sclerosis, Depression and bipolar disorder, Anxiety, PTSD and OCD, Pain and fatigue | Participants148 | Lead sponsorOther | StatusCompleted | Library tests named
|
| NCT07253038 | Start2025 | PhaseObservational | ConditionsDepression and bipolar disorder, Huntington's disease | Participants40 | Lead sponsorOther | StatusRecruiting | Library tests named
|
| NCT07186023 | Start2025 | PhaseNot applicable | ConditionsDepression and bipolar disorder | Participants124 | Lead sponsorOther | StatusRecruiting | Library tests named
|
| NCT07101107 | Start2026 | PhaseObservational | ConditionsDepression and bipolar disorder | Participants160 | Lead sponsorOther | StatusRecruiting | Library tests named
|
| NCT07048938 | Start2025 | PhaseNot applicable | ConditionsDepression and bipolar disorder | Participants120 | Lead sponsorOther | StatusNot yet recruiting | Library tests named
|
| NCT07039903 | Start2025 | PhaseNot applicable | ConditionsDepression and bipolar disorder, ADHD | Participants68 | Lead sponsorOther | StatusNot yet recruiting | Library tests named
|
| NCT06922409 | Start2025 | PhaseNot applicable | ConditionsStroke, Depression and bipolar disorder, Sleep and sleep disorders, Pain and fatigue | Participants45 | Lead sponsorOther | StatusRecruiting | Library tests named
|
| NCT06914284 | Start2024 | PhaseObservational | ConditionsDepression and bipolar disorder | Participants30 | Lead sponsorOther | StatusRecruiting | Library tests named
|
| NCT06897670 | Start2025 | PhaseObservational | ConditionsMild cognitive impairment, Depression and bipolar disorder | Participants200 | Lead sponsorOther | StatusRecruiting | Library tests named
|
| NCT06897553 | Start2024 | PhaseNot applicable | ConditionsBrain injury and concussion, Depression and bipolar disorder, COVID-19 and long COVID, Anxiety, PTSD and OCD | Participants44 | Lead sponsorOther | StatusRecruiting | Library tests named
|
| NCT06893120 | Start2022 | PhaseNot applicable | ConditionsParkinson's disease, Depression and bipolar disorder | Participants20 | Lead sponsorOther | StatusCompleted | Library tests named
|
Questions, answered from the data
How many depression and bipolar disorder trials use Verbal Fluency?
154 registered depression and bipolar disorder studies on ClinicalTrials.gov name it in an outcome measure, 43 of them in a primary outcome: 12% of the condition's 1,247 studies with a cognitive outcome, against 11% of all of them. It is the 3rd most named test in depression and bipolar disorder trials.
Which tests do depression and bipolar disorder trials use with Verbal Fluency?
The Trail Making Test (57 studies), Verbal Learning (56 studies) and the Digit Span Test (56 studies).
How many participants do phase 2 depression and bipolar disorder trials that use Verbal Fluency enroll?
Half of the phase 2 studies that name it enroll 60 participants or fewer, and the middle half enroll 39 to 84. 14 of them give a size.
When do depression and bipolar disorder trials measure Verbal Fluency?
Half of the primary outcomes that name Verbal Fluency are measured within 8 weeks of the start, and the middle half from 4 weeks to 13 weeks. 37 primary outcomes give a duration.
How many completed depression and bipolar disorder trials that use Verbal Fluency have reported results?
32 of the 60 completed studies that name it, 53%, have reported results: 13 posted them on ClinicalTrials.gov, 27 have a results paper linked to the registry record, and 8 did both. The other 28 show neither. Of all completed studies with a cognitive outcome, 46% have reported results.
How the studies are counted
For each test family, the census runs ClinicalTrials.gov's own outcome search for the family's names and reads every study first posted by the day the family was counted. These studies were read on 10 November 2026. A study counts once on a page, however many tests it names. Counts for a test cover every version of the task under any of its names, so a page can count studies that used a commercial version.
The census adds two things to each record and changes nothing in it: which outcome list names the test (primary, then secondary, then other), and the condition groups, matched on the study's condition names and MeSH terms. A study can fall in several groups; one whose only condition is cognitive impairment or decline falls in “Cognitive impairment and decline”. Studies that name only instruments outside the library count in every total and share but are not listed.
A second read on 10 November 2026 added each study's overall status, whether results are posted, its intervention types, the countries of its sites and the time frame of the outcome that names each test. A time frame counts by the latest time point it names: “Baseline, 12 and 24 weeks” is 24 weeks, a single visit is within a day, and one that names no duration, such as “end of treatment”, is left out of the timings.
A third read on 10 November 2026 added the papers the registry links to each study: those its sponsor lists as reporting results, and those PubMed links to it through the study's NCT number. A study has a results paper when one of them came out in or after the month of its primary completion and PubMed does not class it as a protocol, review or comment. A paper that never gives the NCT number is not linked, so some studies counted as reporting neither did publish.
Source: ClinicalTrials.gov, a database of the U.S. National Library of Medicine, which does not endorse these pages. Every study line is in the data release 2.1.0, and the explorer's own file is clinical-trials-studies.json.
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