Clinical trials data
Verbal Fluency in mild cognitive impairment trials: 177 registered studies
Every registered mild cognitive impairment study on ClinicalTrials.gov that names Verbal Fluency in an outcome measure: how often it is a primary outcome, the tests named with it, how large the studies are and when they measure it.
- Registered mild cognitive impairment studies name it in an outcome measure
- 177
- Name it in a primary outcome, 40%
- 70 of 177
Tests named in the same studies
- 1
Trail Making Test86 studies, 27 as a primary outcome
- 2
Verbal Learning69 studies, 37 as a primary outcome
- 3
Digit Span Test67 studies, 27 as a primary outcome
- 4
Category Fluency48 studies, 20 as a primary outcome
- 5
Stroop Color-Word Test48 studies, 17 as a primary outcome
- 6
Picture Naming Test45 studies, 16 as a primary outcome
- 7
Symbol Coding34 studies, 16 as a primary outcome
- 8
Clock Drawing Task26 studies, 14 as a primary outcome
- 9
Short Story Recall22 studies, 12 as a primary outcome
- 10
Complex Figure Copy and Recall17 studies, 6 as a primary outcome
A test as a primary outcomeOnly in secondary or other outcomes
Studies by start year
A test as a primary outcomeOnly in secondary or other outcomes
Show as a table
| Start year | Studies | A test as a primary outcome |
|---|---|---|
| 2000 | 0 | 0 |
| 2001 | 0 | 0 |
| 2002 | 0 | 0 |
| 2003 | 0 | 0 |
| 2004 | 0 | 0 |
| 2005 | 0 | 0 |
| 2006 | 1 | 0 |
| 2007 | 0 | 0 |
| 2008 | 1 | 1 |
| 2009 | 1 | 0 |
| 2010 | 4 | 0 |
| 2011 | 3 | 1 |
| 2012 | 4 | 2 |
| 2013 | 1 | 0 |
| 2014 | 5 | 3 |
| 2015 | 7 | 4 |
| 2016 | 4 | 1 |
| 2017 | 10 | 4 |
| 2018 | 13 | 6 |
| 2019 | 12 | 4 |
| 2020 | 16 | 7 |
| 2021 | 15 | 7 |
| 2022 | 13 | 2 |
| 2023 | 18 | 10 |
| 2024 | 20 | 8 |
| 2025 | 20 | 7 |
| 2026 | 9 | 3 |
Phases and study sizes
By phase
- Early phase 12 studies, 1 as a primary outcome
- Phase 13 studies, 1 as a primary outcome
- Phase 1/22 studies, 1 as a primary outcome
- Phase 213 studies, 6 as a primary outcome
- Phase 32 studies, 1 as a primary outcome
- Phase 41 studies, 1 as a primary outcome
- Not applicable136 studies, 50 as a primary outcome
- Observational18 studies, 9 as a primary outcome
Participants per study
- Phase 299 median, 55 to 151
- Not applicable60 median, 40 to 107
- Observational149 median, 70 to 232
Show as a table
| Phase | Studies with a size | Median | Middle half |
|---|---|---|---|
| Phase 2 | 12 | 99 | 55 to 151 |
| Not applicable | 136 | 60 | 40 to 107 |
| Observational | 18 | 149 | 70 to 232 |
When mild cognitive impairment trials measure it
Latest time point of each outcome
- Within a day11 outcomes, 4 as a primary outcome
- Up to 4 weeks17 outcomes, 4 as a primary outcome
- 1 to 3 months45 outcomes, 21 as a primary outcome
- 3 to 6 months36 outcomes, 16 as a primary outcome
- 6 to 12 months38 outcomes, 11 as a primary outcome
- 1 to 2 years12 outcomes, 7 as a primary outcome
- Over 2 years7 outcomes, 2 as a primary outcome
- No duration given11 outcomes, 5 as a primary outcome
A test as a primary outcomeOnly in secondary or other outcomes
166 of the 177 outcome measures give a duration. A single visit counts as within a day.
Status, results, interventions and countries
Status
- Recruiting34 studies, 11 as a primary outcome
- Not yet recruiting9 studies, 3 as a primary outcome
- Active, not recruiting6 studies, 4 as a primary outcome
- Completed76 studies, 28 as a primary outcome
- Stopped early13 studies, 6 as a primary outcome
- Status unknown39 studies, 18 as a primary outcome
What they test
- Behavioral64 studies, 24 as a primary outcome
- Drug18 studies, 6 as a primary outcome
- Device46 studies, 16 as a primary outcome
- Dietary supplement18 studies, 7 as a primary outcome
- Procedure5 studies, 1 as a primary outcome
- Diagnostic test3 studies, 2 as a primary outcome
- Biological2 studies, 2 as a primary outcome
- Radiation2 studies, 1 as a primary outcome
- Combination product2 studies, 1 as a primary outcome
- Other44 studies, 21 as a primary outcome
- None given4 studies, 3 as a primary outcome
Intervention types as registered. A study can list several; observational studies often list none.
Where their sites are
- United States55 studies, 21 as a primary outcome
- Italy17 studies, 3 as a primary outcome
- Hong Kong11 studies, 2 as a primary outcome
- Spain10 studies, 4 as a primary outcome
- Canada9 studies, 2 as a primary outcome
- Switzerland9 studies, 4 as a primary outcome
- United Kingdom9 studies, 3 as a primary outcome
- Greece7 studies, 6 as a primary outcome
- Taiwan7 studies, 5 as a primary outcome
- South Korea6 studies, 3 as a primary outcome
- Brazil5 studies, 1 as a primary outcome
- Germany5 studies, 1 as a primary outcome
34 countries in all. A study with sites in several counts in each; 12 list no site.
Reported results
Completed studies with results posted on ClinicalTrials.gov, a results paper the registry links to the study, or both.
Completed mild cognitive impairment studies that name Verbal Fluency: 44 of 76, 58%
Every completed study with a cognitive outcome: 3,626 of 7,953, 46%
| Results | Completed mild cognitive impairment studies that name Verbal Fluency | Every completed study |
|---|---|---|
| Results on ClinicalTrials.gov and a paper | 12, 16% | 776, 10% |
| Results on ClinicalTrials.gov only | 12, 16% | 1,139, 14% |
| A results paper only | 20, 26% | 1,711, 22% |
| Neither | 32, 42% | 4,327, 54% |
The 177 studies
177 studies match. 70 name Verbal Fluency in a primary outcome. Median size 66 participants. Median time to the primary outcome: 5 months.
Loading 177 studies; the filters turn on when they arrive.
2026 is partly planned starts.
Show as a table
| Start year | Studies | As a primary outcome |
|---|---|---|
| 2000 | 0 | 0 |
| 2001 | 0 | 0 |
| 2002 | 0 | 0 |
| 2003 | 0 | 0 |
| 2004 | 0 | 0 |
| 2005 | 0 | 0 |
| 2006 | 1 | 0 |
| 2007 | 0 | 0 |
| 2008 | 1 | 1 |
| 2009 | 1 | 0 |
| 2010 | 4 | 0 |
| 2011 | 3 | 1 |
| 2012 | 4 | 2 |
| 2013 | 1 | 0 |
| 2014 | 5 | 3 |
| 2015 | 7 | 4 |
| 2016 | 4 | 1 |
| 2017 | 10 | 4 |
| 2018 | 13 | 6 |
| 2019 | 12 | 4 |
| 2020 | 16 | 7 |
| 2021 | 15 | 7 |
| 2022 | 13 | 2 |
| 2023 | 18 | 10 |
| 2024 | 20 | 8 |
| 2025 | 20 | 7 |
| 2026 | 9 | 3 |
Library tests named most
Largest condition groups
Phases
Participants
Lead sponsor: industry 15, other 162. Interventional 159, observational 18.
As a primary outcomeSecondary or other outcomeVerbal Fluency
The studies, newest registration first
Each number opens the study's record on ClinicalTrials.gov.
| Study | Start | Phase | Conditions | Participants | Lead sponsor | Status | Library tests named, with the latest time point |
|---|---|---|---|---|---|---|---|
| NCT07883148 | Start2024 | PhaseNot applicable | ConditionsDementia and Alzheimer's, Mild cognitive impairment | Participants52 | Lead sponsorOther | StatusCompleted | Library tests named
|
| NCT07842146 | Start2026 | PhaseNot applicable | ConditionsDementia and Alzheimer's, Mild cognitive impairment | Participants60 | Lead sponsorOther | StatusRecruiting | Library tests named
|
| NCT07733726 | Start2025 | PhaseNot applicable | ConditionsMild cognitive impairment, Aging, frailty and exercise | Participants66 | Lead sponsorOther | StatusRecruiting | Library tests named
|
| NCT07731334 | Start2026 | PhaseNot applicable | ConditionsDementia and Alzheimer's, Mild cognitive impairment | Participants384 | Lead sponsorOther | StatusRecruiting | Library tests named
|
| NCT07651085 | Start2024 | PhaseObservational | ConditionsDementia and Alzheimer's, Mild cognitive impairment, Parkinson's disease, Sleep and sleep disorders | Participants65 | Lead sponsorOther | StatusActive, not recruiting | Library tests named
|
| NCT07608510 | Start2026 | PhaseObservational | ConditionsMild cognitive impairment | Participants150 | Lead sponsorOther | StatusNot yet recruiting | Library tests named
|
| NCT07596940 | Start2023 | PhaseNot applicable | ConditionsMild cognitive impairment | Participants9 | Lead sponsorOther | StatusCompleted | Library tests named
|
| NCT07517380 | Start2026 | PhaseNot applicable | ConditionsMild cognitive impairment | Participants40 | Lead sponsorOther | StatusRecruiting | Library tests named
|
| NCT07512193 | Start2026 | PhaseNot applicable | ConditionsMild cognitive impairment | Participants10 | Lead sponsorOther | StatusNot yet recruiting | Library tests named
|
| NCT07466615 | Start2026 | PhaseNot applicable | ConditionsMild cognitive impairment | Participants40 | Lead sponsorOther | StatusNot yet recruiting | Library tests named
|
| NCT07402356 | Start2025 | PhaseObservational | ConditionsDementia and Alzheimer's, Mild cognitive impairment, Depression and bipolar disorder | Participants140 | Lead sponsorOther | StatusRecruiting | Library tests named
|
| NCT07385937 | Start2026 | PhaseNot applicable | ConditionsDementia and Alzheimer's, Mild cognitive impairment | Participants150 | Lead sponsorOther | StatusNot yet recruiting | Library tests named
|
| NCT07366346 | Start2026 | PhaseNot applicable | ConditionsDementia and Alzheimer's, Mild cognitive impairment | Participants100 | Lead sponsorOther | StatusRecruiting | Library tests named
|
| NCT07334392 | Start2025 | PhaseNot applicable | ConditionsMild cognitive impairment | Participants45 | Lead sponsorOther | StatusRecruiting | Library tests named
|
| NCT07321821 | Start2025 | PhaseNot applicable | ConditionsMild cognitive impairment | Participants60 | Lead sponsorOther | StatusActive, not recruiting | Library tests named
|
| NCT07286448 | Start2025 | PhaseNot applicable | ConditionsMild cognitive impairment | Participants100 | Lead sponsorOther | StatusRecruiting | Library tests named
|
| NCT07248709 | Start2025 | PhaseNot applicable | ConditionsMild cognitive impairment | Participants68 | Lead sponsorOther | StatusCompleted | Library tests named
|
| NCT07241598 | Start2025 | PhaseNot applicable | ConditionsDementia and Alzheimer's, Mild cognitive impairment | Participants70 | Lead sponsorOther | StatusNot yet recruiting | Library tests named
|
| NCT07149038 | Start2025 | PhaseNot applicable | ConditionsDementia and Alzheimer's, Mild cognitive impairment | Participants24 | Lead sponsorIndustry | StatusActive, not recruiting | Library tests named
|
| NCT07105800 | Start2025 | PhaseNot applicable | ConditionsMild cognitive impairment, Aging, frailty and exercise | Participants50 | Lead sponsorOther | StatusRecruiting | Library tests named
|
| NCT07064226 | Start2025 | PhaseNot applicable | ConditionsDementia and Alzheimer's, Mild cognitive impairment | Participants102 | Lead sponsorOther | StatusRecruiting | Library tests named
|
| NCT07039708 | Start2025 | PhaseNot applicable | ConditionsMild cognitive impairment, Healthy volunteers, Aging, frailty and exercise | Participants60 | Lead sponsorOther | StatusStopped early | Library tests named
|
| NCT07002996 | Start2025 | PhaseNot applicable | ConditionsMild cognitive impairment | Participants80 | Lead sponsorOther | StatusRecruiting | Library tests named
|
| NCT06935812 | Start2025 | PhaseNot applicable | ConditionsMild cognitive impairment | Participants106 | Lead sponsorOther | StatusRecruiting | Library tests named
|
| NCT06897670 | Start2025 | PhaseObservational | ConditionsMild cognitive impairment, Depression and bipolar disorder | Participants200 | Lead sponsorOther | StatusRecruiting | Library tests named
|
Questions, answered from the data
How many mild cognitive impairment trials use Verbal Fluency?
177 registered mild cognitive impairment studies on ClinicalTrials.gov name it in an outcome measure, 70 of them in a primary outcome: 21% of the condition's 859 studies with a cognitive outcome, against 11% of all of them. It is the 3rd most named test in mild cognitive impairment trials.
Which tests do mild cognitive impairment trials use with Verbal Fluency?
The Trail Making Test (86 studies), Verbal Learning (69 studies) and the Digit Span Test (67 studies).
How many participants do phase 2 mild cognitive impairment trials that use Verbal Fluency enroll?
Half of the phase 2 studies that name it enroll 99 participants or fewer, and the middle half enroll 55 to 151. 12 of them give a size.
When do mild cognitive impairment trials measure Verbal Fluency?
Half of the primary outcomes that name Verbal Fluency are measured within 5 months of the start, and the middle half from 10 weeks to 9 months. 65 primary outcomes give a duration.
How many completed mild cognitive impairment trials that use Verbal Fluency have reported results?
44 of the 76 completed studies that name it, 58%, have reported results: 24 posted them on ClinicalTrials.gov, 32 have a results paper linked to the registry record, and 12 did both. The other 32 show neither. Of all completed studies with a cognitive outcome, 46% have reported results.
How the studies are counted
For each test family, the census runs ClinicalTrials.gov's own outcome search for the family's names and reads every study first posted by the day the family was counted. These studies were read on 10 November 2026. A study counts once on a page, however many tests it names. Counts for a test cover every version of the task under any of its names, so a page can count studies that used a commercial version.
The census adds two things to each record and changes nothing in it: which outcome list names the test (primary, then secondary, then other), and the condition groups, matched on the study's condition names and MeSH terms. A study can fall in several groups; one whose only condition is cognitive impairment or decline falls in “Cognitive impairment and decline”. Studies that name only instruments outside the library count in every total and share but are not listed.
A second read on 10 November 2026 added each study's overall status, whether results are posted, its intervention types, the countries of its sites and the time frame of the outcome that names each test. A time frame counts by the latest time point it names: “Baseline, 12 and 24 weeks” is 24 weeks, a single visit is within a day, and one that names no duration, such as “end of treatment”, is left out of the timings.
A third read on 10 November 2026 added the papers the registry links to each study: those its sponsor lists as reporting results, and those PubMed links to it through the study's NCT number. A study has a results paper when one of them came out in or after the month of its primary completion and PubMed does not class it as a protocol, review or comment. A paper that never gives the NCT number is not linked, so some studies counted as reporting neither did publish.
Source: ClinicalTrials.gov, a database of the U.S. National Library of Medicine, which does not endorse these pages. Every study line is in the data release 2.1.0, and the explorer's own file is clinical-trials-studies.json.
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