Clinical trials data
Verbal Fluency in dementia and Alzheimer's trials: 248 registered studies
Every registered dementia and Alzheimer's disease study on ClinicalTrials.gov that names Verbal Fluency in an outcome measure: how often it is a primary outcome, the tests named with it, how large the studies are and when they measure it.
- Registered dementia and Alzheimer's disease studies name it in an outcome measure
- 248
- Name it in a primary outcome, 38%
- 95 of 248
Tests named in the same studies
- 1
Trail Making Test101 studies, 37 as a primary outcome
- 2
Category Fluency93 studies, 29 as a primary outcome
- 3
Verbal Learning80 studies, 39 as a primary outcome
- 4
Digit Span Test76 studies, 26 as a primary outcome
- 5
Picture Naming Test45 studies, 20 as a primary outcome
- 6
Symbol Coding42 studies, 17 as a primary outcome
- 7
Stroop Color-Word Test40 studies, 20 as a primary outcome
- 8
Complex Figure Copy and Recall31 studies, 14 as a primary outcome
- 9
Clock Drawing Task26 studies, 11 as a primary outcome
- 10
Short Story Recall26 studies, 10 as a primary outcome
A test as a primary outcomeOnly in secondary or other outcomes
Studies by start year
A test as a primary outcomeOnly in secondary or other outcomes
Show as a table
| Start year | Studies | A test as a primary outcome |
|---|---|---|
| 2000 | 0 | 0 |
| 2001 | 0 | 0 |
| 2002 | 0 | 0 |
| 2003 | 0 | 0 |
| 2004 | 1 | 0 |
| 2005 | 7 | 2 |
| 2006 | 2 | 1 |
| 2007 | 4 | 0 |
| 2008 | 4 | 1 |
| 2009 | 4 | 1 |
| 2010 | 5 | 1 |
| 2011 | 5 | 3 |
| 2012 | 6 | 2 |
| 2013 | 9 | 4 |
| 2014 | 6 | 5 |
| 2015 | 8 | 4 |
| 2016 | 9 | 2 |
| 2017 | 14 | 4 |
| 2018 | 20 | 8 |
| 2019 | 23 | 9 |
| 2020 | 12 | 8 |
| 2021 | 12 | 5 |
| 2022 | 25 | 9 |
| 2023 | 18 | 6 |
| 2024 | 20 | 8 |
| 2025 | 20 | 8 |
| 2026 | 13 | 4 |
Phases and study sizes
By phase
- Early phase 12 studies, 1 as a primary outcome
- Phase 16 studies, 1 as a primary outcome
- Phase 1/26 studies, 3 as a primary outcome
- Phase 245 studies, 14 as a primary outcome
- Phase 2/33 studies, 1 as a primary outcome
- Phase 313 studies, 1 as a primary outcome
- Phase 47 studies, 1 as a primary outcome
- Not applicable125 studies, 48 as a primary outcome
- Observational41 studies, 25 as a primary outcome
Participants per study
- Phase 266 median, 42 to 160
- Phase 3535 median, 400 to 975
- Not applicable60 median, 33 to 136
- Observational152 median, 77 to 746
Show as a table
| Phase | Studies with a size | Median | Middle half |
|---|---|---|---|
| Phase 2 | 44 | 66 | 42 to 160 |
| Phase 3 | 13 | 535 | 400 to 975 |
| Not applicable | 123 | 60 | 33 to 136 |
| Observational | 38 | 152 | 77 to 746 |
When dementia and Alzheimer's trials measure it
Latest time point of each outcome
- Within a day19 outcomes, 9 as a primary outcome
- Up to 4 weeks17 outcomes, 6 as a primary outcome
- 1 to 3 months56 outcomes, 23 as a primary outcome
- 3 to 6 months55 outcomes, 19 as a primary outcome
- 6 to 12 months47 outcomes, 15 as a primary outcome
- 1 to 2 years21 outcomes, 5 as a primary outcome
- Over 2 years20 outcomes, 10 as a primary outcome
- No duration given13 outcomes, 8 as a primary outcome
A test as a primary outcomeOnly in secondary or other outcomes
235 of the 248 outcome measures give a duration. A single visit counts as within a day.
Status, results, interventions and countries
Status
- Recruiting40 studies, 13 as a primary outcome
- Not yet recruiting11 studies, 4 as a primary outcome
- Active, not recruiting13 studies, 4 as a primary outcome
- Completed119 studies, 46 as a primary outcome
- Stopped early29 studies, 12 as a primary outcome
- Status unknown36 studies, 16 as a primary outcome
What they test
- Behavioral56 studies, 27 as a primary outcome
- Drug71 studies, 19 as a primary outcome
- Device55 studies, 18 as a primary outcome
- Dietary supplement10 studies, 2 as a primary outcome
- Procedure9 studies, 4 as a primary outcome
- Diagnostic test7 studies, 2 as a primary outcome
- Biological14 studies, 2 as a primary outcome
- Radiation3 studies, 2 as a primary outcome
- Genetic1 studies, 1 as a primary outcome
- Other58 studies, 20 as a primary outcome
- None given15 studies, 13 as a primary outcome
Intervention types as registered. A study can list several; observational studies often list none.
Where their sites are
- United States98 studies, 36 as a primary outcome
- Italy26 studies, 8 as a primary outcome
- Canada22 studies, 5 as a primary outcome
- Spain22 studies, 9 as a primary outcome
- France18 studies, 3 as a primary outcome
- United Kingdom16 studies, 7 as a primary outcome
- Australia15 studies, 2 as a primary outcome
- China14 studies, 5 as a primary outcome
- Germany14 studies, 3 as a primary outcome
- South Korea11 studies, 5 as a primary outcome
- Japan8 studies, 0 as a primary outcome
- Netherlands8 studies, 2 as a primary outcome
54 countries in all. A study with sites in several counts in each; 12 list no site.
Reported results
Completed studies with results posted on ClinicalTrials.gov, a results paper the registry links to the study, or both.
Completed dementia and Alzheimer's disease studies that name Verbal Fluency: 76 of 119, 64%
Every completed study with a cognitive outcome: 3,626 of 7,953, 46%
| Results | Completed dementia and Alzheimer's disease studies that name Verbal Fluency | Every completed study |
|---|---|---|
| Results on ClinicalTrials.gov and a paper | 32, 27% | 776, 10% |
| Results on ClinicalTrials.gov only | 17, 14% | 1,139, 14% |
| A results paper only | 27, 23% | 1,711, 22% |
| Neither | 43, 36% | 4,327, 54% |
The 248 studies
248 studies match. 95 name Verbal Fluency in a primary outcome. Median size 70 participants. Median time to the primary outcome: 5 months.
Loading 248 studies; the filters turn on when they arrive.
2026 is partly planned starts. Not shown: 1 planned to start after 2026.
Show as a table
| Start year | Studies | As a primary outcome |
|---|---|---|
| 2000 | 0 | 0 |
| 2001 | 0 | 0 |
| 2002 | 0 | 0 |
| 2003 | 0 | 0 |
| 2004 | 1 | 0 |
| 2005 | 7 | 2 |
| 2006 | 2 | 1 |
| 2007 | 4 | 0 |
| 2008 | 4 | 1 |
| 2009 | 4 | 1 |
| 2010 | 5 | 1 |
| 2011 | 5 | 3 |
| 2012 | 6 | 2 |
| 2013 | 9 | 4 |
| 2014 | 6 | 5 |
| 2015 | 8 | 4 |
| 2016 | 9 | 2 |
| 2017 | 14 | 4 |
| 2018 | 20 | 8 |
| 2019 | 23 | 9 |
| 2020 | 12 | 8 |
| 2021 | 12 | 5 |
| 2022 | 25 | 9 |
| 2023 | 18 | 6 |
| 2024 | 20 | 8 |
| 2025 | 20 | 8 |
| 2026 | 13 | 4 |
Library tests named most
Largest condition groups
Phases
Participants
Lead sponsor: industry 50, NIH 2, other 196. Interventional 207, observational 41.
As a primary outcomeSecondary or other outcomeVerbal Fluency
The studies, newest registration first
Each number opens the study's record on ClinicalTrials.gov.
| Study | Start | Phase | Conditions | Participants | Lead sponsor | Status | Library tests named, with the latest time point |
|---|---|---|---|---|---|---|---|
| NCT07883148 | Start2024 | PhaseNot applicable | ConditionsDementia and Alzheimer's, Mild cognitive impairment | Participants52 | Lead sponsorOther | StatusCompleted | Library tests named
|
| NCT07842146 | Start2026 | PhaseNot applicable | ConditionsDementia and Alzheimer's, Mild cognitive impairment | Participants60 | Lead sponsorOther | StatusRecruiting | Library tests named
|
| NCT07841145 | Start2026 | PhaseNot applicable | ConditionsDementia and Alzheimer's, Aging, frailty and exercise | Participants68 | Lead sponsorOther | StatusNot yet recruiting | Library tests named
|
| NCT07741071 | Start2026 | PhasePhase 2 | ConditionsDementia and Alzheimer's | Participants270 | Lead sponsorOther | StatusRecruiting | Library tests named
|
| NCT07731334 | Start2026 | PhaseNot applicable | ConditionsDementia and Alzheimer's, Mild cognitive impairment | Participants384 | Lead sponsorOther | StatusRecruiting | Library tests named
|
| NCT07722169 | Start2026 | PhaseNot applicable | ConditionsDementia and Alzheimer's | Participants48 | Lead sponsorOther | StatusNot yet recruiting | Library tests named
|
| NCT07664865 | Start2024 | PhaseObservational | ConditionsDementia and Alzheimer's | Participants250 | Lead sponsorOther | StatusCompleted | Library tests named
|
| NCT07651085 | Start2024 | PhaseObservational | ConditionsDementia and Alzheimer's, Mild cognitive impairment, Parkinson's disease, Sleep and sleep disorders | Participants65 | Lead sponsorOther | StatusActive, not recruiting | Library tests named
|
| NCT07645638 | Start2025 | PhaseNot applicable | ConditionsDementia and Alzheimer's | Participants33 | Lead sponsorOther | StatusCompleted | Library tests named
|
| NCT07642726 | Start2018 | PhaseObservational | ConditionsDementia and Alzheimer's, Aging, frailty and exercise | Participants276 | Lead sponsorOther | StatusCompleted | Library tests named
|
| NCT07638813 | Start2026 | PhasePhase 1/2 | ConditionsDementia and Alzheimer's | Participants33 | Lead sponsorOther | StatusNot yet recruiting | Library tests named
|
| NCT07598617 | Start2026 | PhaseObservational | ConditionsDementia and Alzheimer's | Participants120 | Lead sponsorOther | StatusRecruiting | Library tests named
|
| NCT07505784 | Start2026 | PhaseNot applicable | ConditionsDementia and Alzheimer's | Participants30 | Lead sponsorOther | StatusRecruiting | Library tests named
|
| NCT07452939 | Start2026 | PhaseNot applicable | ConditionsDementia and Alzheimer's, Delirium, surgery and intensive care | Participants40 | Lead sponsorOther | StatusRecruiting | Library tests named
|
| NCT07402356 | Start2025 | PhaseObservational | ConditionsDementia and Alzheimer's, Mild cognitive impairment, Depression and bipolar disorder | Participants140 | Lead sponsorOther | StatusRecruiting | Library tests named
|
| NCT07399418 | Start2025 | PhaseObservational | ConditionsDementia and Alzheimer's | Participants80 | Lead sponsorOther | StatusRecruiting | Library tests named
|
| NCT07385937 | Start2026 | PhaseNot applicable | ConditionsDementia and Alzheimer's, Mild cognitive impairment | Participants150 | Lead sponsorOther | StatusNot yet recruiting | Library tests named
|
| NCT07375771 | Start2025 | PhaseNot applicable | ConditionsDementia and Alzheimer's | Participants40 | Lead sponsorOther | StatusRecruiting | Library tests named
|
| NCT07366346 | Start2026 | PhaseNot applicable | ConditionsDementia and Alzheimer's, Mild cognitive impairment | Participants100 | Lead sponsorOther | StatusRecruiting | Library tests named
|
| NCT07332260 | Start2026 | PhasePhase 1 | ConditionsDementia and Alzheimer's | Participants10 | Lead sponsorOther | StatusRecruiting | Library tests named
|
| NCT07312435 | Start2025 | PhaseNot applicable | ConditionsDementia and Alzheimer's | Participants96 | Lead sponsorOther | StatusRecruiting | Library tests named
|
| NCT07272863 | Start2026 | PhaseNot applicable | ConditionsDementia and Alzheimer's, Aging, frailty and exercise, Sleep and sleep disorders | Participants214 | Lead sponsorOther | StatusNot yet recruiting | Library tests named
|
| NCT07241598 | Start2025 | PhaseNot applicable | ConditionsDementia and Alzheimer's, Mild cognitive impairment | Participants70 | Lead sponsorOther | StatusNot yet recruiting | Library tests named
|
| NCT07205003 | Start2022 | PhaseObservational | ConditionsDementia and Alzheimer's | Participants140 | Lead sponsorOther | StatusRecruiting | Library tests named
|
| NCT07154511 | Start2025 | PhasePhase 1/2 | ConditionsDementia and Alzheimer's, Parkinson's disease | Participants45 | Lead sponsorOther | StatusRecruiting | Library tests named
|
Questions, answered from the data
How many dementia and Alzheimer's trials use Verbal Fluency?
248 registered dementia and Alzheimer's disease studies on ClinicalTrials.gov name it in an outcome measure, 95 of them in a primary outcome: 15% of the condition's 1,673 studies with a cognitive outcome, against 11% of all of them. It is the 2nd most named test in dementia and Alzheimer's trials.
Which tests do dementia and Alzheimer's trials use with Verbal Fluency?
The Trail Making Test (101 studies), Category Fluency (93 studies) and Verbal Learning (80 studies).
How many participants do phase 2 dementia and Alzheimer's trials that use Verbal Fluency enroll?
Half of the phase 2 studies that name it enroll 66 participants or fewer, and the middle half enroll 42 to 160. 44 of them give a size.
When do dementia and Alzheimer's trials measure Verbal Fluency?
Half of the primary outcomes that name Verbal Fluency are measured within 5 months of the start, and the middle half from 9 weeks to 10 months. 87 primary outcomes give a duration.
How many completed dementia and Alzheimer's trials that use Verbal Fluency have reported results?
76 of the 119 completed studies that name it, 64%, have reported results: 49 posted them on ClinicalTrials.gov, 59 have a results paper linked to the registry record, and 32 did both. The other 43 show neither. Of all completed studies with a cognitive outcome, 46% have reported results.
How the studies are counted
For each test family, the census runs ClinicalTrials.gov's own outcome search for the family's names and reads every study first posted by the day the family was counted. These studies were read on 10 November 2026. A study counts once on a page, however many tests it names. Counts for a test cover every version of the task under any of its names, so a page can count studies that used a commercial version.
The census adds two things to each record and changes nothing in it: which outcome list names the test (primary, then secondary, then other), and the condition groups, matched on the study's condition names and MeSH terms. A study can fall in several groups; one whose only condition is cognitive impairment or decline falls in “Cognitive impairment and decline”. Studies that name only instruments outside the library count in every total and share but are not listed.
A second read on 10 November 2026 added each study's overall status, whether results are posted, its intervention types, the countries of its sites and the time frame of the outcome that names each test. A time frame counts by the latest time point it names: “Baseline, 12 and 24 weeks” is 24 weeks, a single visit is within a day, and one that names no duration, such as “end of treatment”, is left out of the timings.
A third read on 10 November 2026 added the papers the registry links to each study: those its sponsor lists as reporting results, and those PubMed links to it through the study's NCT number. A study has a results paper when one of them came out in or after the month of its primary completion and PubMed does not class it as a protocol, review or comment. A paper that never gives the NCT number is not linked, so some studies counted as reporting neither did publish.
Source: ClinicalTrials.gov, a database of the U.S. National Library of Medicine, which does not endorse these pages. Every study line is in the data release 2.1.0, and the explorer's own file is clinical-trials-studies.json.
Run Verbal Fluency in your trial
Choose tests with a record in registered trials, and run them in a browser at every site, on the same version each visit.