Clinical trials data
Category Fluency in dementia and Alzheimer's trials: 167 registered studies
Every registered dementia and Alzheimer's disease study on ClinicalTrials.gov that names Category Fluency in an outcome measure: how often it is a primary outcome, the tests named with it, how large the studies are and when they measure it.
- Registered dementia and Alzheimer's disease studies name it in an outcome measure
- 167
- Name it in a primary outcome, 30%
- 50 of 167
Tests named in the same studies
- 1
Verbal Fluency93 studies, 28 as a primary outcome
- 2
Trail Making Test71 studies, 28 as a primary outcome
- 3
Digit Span Test65 studies, 20 as a primary outcome
- 4
Verbal Learning57 studies, 27 as a primary outcome
- 5
Symbol Coding42 studies, 19 as a primary outcome
- 6
Short Story Recall39 studies, 18 as a primary outcome
- 7
Picture Naming Test39 studies, 13 as a primary outcome
- 8
Selective Reminding Task23 studies, 7 as a primary outcome
- 9
Stroop Color-Word Test19 studies, 8 as a primary outcome
- 10
Clock Drawing Task17 studies, 8 as a primary outcome
A test as a primary outcomeOnly in secondary or other outcomes
Studies by start year
A test as a primary outcomeOnly in secondary or other outcomes
Show as a table
| Start year | Studies | A test as a primary outcome |
|---|---|---|
| 2000 | 0 | 0 |
| 2001 | 0 | 0 |
| 2002 | 0 | 0 |
| 2003 | 1 | 0 |
| 2004 | 2 | 0 |
| 2005 | 3 | 1 |
| 2006 | 0 | 0 |
| 2007 | 1 | 0 |
| 2008 | 2 | 0 |
| 2009 | 2 | 1 |
| 2010 | 3 | 0 |
| 2011 | 5 | 4 |
| 2012 | 6 | 2 |
| 2013 | 4 | 1 |
| 2014 | 3 | 1 |
| 2015 | 6 | 1 |
| 2016 | 8 | 2 |
| 2017 | 6 | 0 |
| 2018 | 9 | 6 |
| 2019 | 12 | 4 |
| 2020 | 7 | 1 |
| 2021 | 16 | 6 |
| 2022 | 17 | 7 |
| 2023 | 14 | 4 |
| 2024 | 10 | 2 |
| 2025 | 17 | 3 |
| 2026 | 9 | 3 |
Phases and study sizes
By phase
- Early phase 13 studies, 1 as a primary outcome
- Phase 17 studies, 0 as a primary outcome
- Phase 1/25 studies, 0 as a primary outcome
- Phase 250 studies, 17 as a primary outcome
- Phase 2/34 studies, 0 as a primary outcome
- Phase 314 studies, 3 as a primary outcome
- Phase 43 studies, 0 as a primary outcome
- Not applicable60 studies, 18 as a primary outcome
- Observational21 studies, 11 as a primary outcome
Participants per study
- Phase 289 median, 42 to 162
- Phase 3755 median, 279 to 1,550
- Not applicable58 median, 35 to 121
- Observational417 median, 90 to 1,697
Show as a table
| Phase | Studies with a size | Median | Middle half |
|---|---|---|---|
| Phase 2 | 48 | 89 | 42 to 162 |
| Phase 3 | 14 | 755 | 279 to 1,550 |
| Not applicable | 60 | 58 | 35 to 121 |
| Observational | 19 | 417 | 90 to 1,697 |
When dementia and Alzheimer's trials measure it
Latest time point of each outcome
- Within a day4 outcomes, 3 as a primary outcome
- Up to 4 weeks5 outcomes, 1 as a primary outcome
- 1 to 3 months29 outcomes, 10 as a primary outcome
- 3 to 6 months50 outcomes, 15 as a primary outcome
- 6 to 12 months20 outcomes, 4 as a primary outcome
- 1 to 2 years26 outcomes, 5 as a primary outcome
- Over 2 years21 outcomes, 7 as a primary outcome
- No duration given11 outcomes, 5 as a primary outcome
A test as a primary outcomeOnly in secondary or other outcomes
155 of the 166 outcome measures give a duration. A single visit counts as within a day.
Status, results, interventions and countries
Status
- Recruiting32 studies, 8 as a primary outcome
- Not yet recruiting7 studies, 0 as a primary outcome
- Active, not recruiting14 studies, 5 as a primary outcome
- Completed81 studies, 25 as a primary outcome
- Stopped early23 studies, 9 as a primary outcome
- Status unknown10 studies, 3 as a primary outcome
What they test
- Behavioral30 studies, 11 as a primary outcome
- Drug73 studies, 15 as a primary outcome
- Device29 studies, 9 as a primary outcome
- Dietary supplement6 studies, 2 as a primary outcome
- Procedure1 studies, 1 as a primary outcome
- Diagnostic test3 studies, 1 as a primary outcome
- Biological12 studies, 2 as a primary outcome
- Radiation4 studies, 2 as a primary outcome
- Combination product1 studies, 1 as a primary outcome
- Genetic1 studies, 1 as a primary outcome
- Other30 studies, 14 as a primary outcome
- None given11 studies, 8 as a primary outcome
Intervention types as registered. A study can list several; observational studies often list none.
Where their sites are
- United States82 studies, 26 as a primary outcome
- Canada24 studies, 6 as a primary outcome
- Spain23 studies, 7 as a primary outcome
- United Kingdom23 studies, 8 as a primary outcome
- Australia20 studies, 3 as a primary outcome
- Italy20 studies, 9 as a primary outcome
- Sweden14 studies, 4 as a primary outcome
- Germany13 studies, 3 as a primary outcome
- France11 studies, 2 as a primary outcome
- Japan11 studies, 1 as a primary outcome
- Netherlands11 studies, 2 as a primary outcome
- Taiwan10 studies, 2 as a primary outcome
49 countries in all. A study with sites in several counts in each; 8 list no site.
Reported results
Completed studies with results posted on ClinicalTrials.gov, a results paper the registry links to the study, or both.
Completed dementia and Alzheimer's disease studies that name Category Fluency: 56 of 81, 69%
Every completed study with a cognitive outcome: 3,626 of 7,953, 46%
| Results | Completed dementia and Alzheimer's disease studies that name Category Fluency | Every completed study |
|---|---|---|
| Results on ClinicalTrials.gov and a paper | 28, 35% | 776, 10% |
| Results on ClinicalTrials.gov only | 10, 12% | 1,139, 14% |
| A results paper only | 18, 22% | 1,711, 22% |
| Neither | 25, 31% | 4,327, 54% |
The 167 studies
167 studies match. 50 name Category Fluency in a primary outcome. Median size 81 participants. Median time to the primary outcome: 6 months.
Loading 167 studies; the filters turn on when they arrive.
2026 is partly planned starts. Not shown: 1 that started before 2000 and 3 planned to start after 2026.
Show as a table
| Start year | Studies | As a primary outcome |
|---|---|---|
| 2000 | 0 | 0 |
| 2001 | 0 | 0 |
| 2002 | 0 | 0 |
| 2003 | 1 | 0 |
| 2004 | 2 | 0 |
| 2005 | 3 | 1 |
| 2006 | 0 | 0 |
| 2007 | 1 | 0 |
| 2008 | 2 | 0 |
| 2009 | 2 | 1 |
| 2010 | 3 | 0 |
| 2011 | 5 | 4 |
| 2012 | 6 | 2 |
| 2013 | 4 | 1 |
| 2014 | 3 | 1 |
| 2015 | 6 | 1 |
| 2016 | 8 | 2 |
| 2017 | 6 | 0 |
| 2018 | 9 | 6 |
| 2019 | 12 | 4 |
| 2020 | 7 | 1 |
| 2021 | 16 | 6 |
| 2022 | 17 | 7 |
| 2023 | 14 | 4 |
| 2024 | 10 | 2 |
| 2025 | 17 | 3 |
| 2026 | 9 | 3 |
Library tests named most
Largest condition groups
Phases
Participants
Lead sponsor: industry 48, other 119. Interventional 146, observational 21.
As a primary outcomeSecondary or other outcomeCategory Fluency
The studies, newest registration first
Each number opens the study's record on ClinicalTrials.gov.
| Study | Start | Phase | Conditions | Participants | Lead sponsor | Status | Library tests named, with the latest time point |
|---|---|---|---|---|---|---|---|
| NCT07882251 | Start2021 | PhaseNot applicable | ConditionsDementia and Alzheimer's | Participants80 | Lead sponsorOther | StatusCompleted | Library tests named
|
| NCT07842146 | Start2026 | PhaseNot applicable | ConditionsDementia and Alzheimer's, Mild cognitive impairment | Participants60 | Lead sponsorOther | StatusRecruiting | Library tests named
|
| NCT07839650 | Start2026 | PhaseNot applicable | ConditionsDementia and Alzheimer's | Participants30 | Lead sponsorOther | StatusRecruiting | Library tests named
|
| NCT07786116 | Start2025 | PhaseNot applicable | ConditionsDementia and Alzheimer's, Mild cognitive impairment, Parkinson's disease, Sleep and sleep disorders | Participants215 | Lead sponsorOther | StatusRecruiting | Library tests named
|
| NCT07722169 | Start2026 | PhaseNot applicable | ConditionsDementia and Alzheimer's | Participants48 | Lead sponsorOther | StatusNot yet recruiting | Library tests named
|
| NCT07717411 | Start2026 | PhasePhase 3 | ConditionsDementia and Alzheimer's | Participants1,600 | Lead sponsorIndustry | StatusRecruiting | Library tests named
|
| NCT07651085 | Start2024 | PhaseObservational | ConditionsDementia and Alzheimer's, Mild cognitive impairment, Parkinson's disease, Sleep and sleep disorders | Participants65 | Lead sponsorOther | StatusActive, not recruiting | Library tests named
|
| NCT07638813 | Start2026 | PhasePhase 1/2 | ConditionsDementia and Alzheimer's | Participants33 | Lead sponsorOther | StatusNot yet recruiting | Library tests named
|
| NCT07505784 | Start2026 | PhaseNot applicable | ConditionsDementia and Alzheimer's | Participants30 | Lead sponsorOther | StatusRecruiting | Library tests named
|
| NCT07402356 | Start2025 | PhaseObservational | ConditionsDementia and Alzheimer's, Mild cognitive impairment, Depression and bipolar disorder | Participants140 | Lead sponsorOther | StatusRecruiting | Library tests named
|
| NCT07399418 | Start2025 | PhaseObservational | ConditionsDementia and Alzheimer's | Participants80 | Lead sponsorOther | StatusRecruiting | Library tests named
|
| NCT07392723 | Start2025 | PhasePhase 2 | ConditionsDementia and Alzheimer's, Aging, frailty and exercise | Participants20 | Lead sponsorOther | StatusRecruiting | Library tests named
|
| NCT07385937 | Start2026 | PhaseNot applicable | ConditionsDementia and Alzheimer's, Mild cognitive impairment | Participants150 | Lead sponsorOther | StatusNot yet recruiting | Library tests named
|
| NCT07375771 | Start2025 | PhaseNot applicable | ConditionsDementia and Alzheimer's | Participants40 | Lead sponsorOther | StatusRecruiting | Library tests named
|
| NCT07366346 | Start2026 | PhaseNot applicable | ConditionsDementia and Alzheimer's, Mild cognitive impairment | Participants100 | Lead sponsorOther | StatusRecruiting | Library tests named
|
| NCT07241598 | Start2025 | PhaseNot applicable | ConditionsDementia and Alzheimer's, Mild cognitive impairment | Participants70 | Lead sponsorOther | StatusNot yet recruiting | Library tests named
|
| NCT07210528 | Start2025 | PhasePhase 1 | ConditionsDementia and Alzheimer's, Mild cognitive impairment | Participants48 | Lead sponsorOther | StatusActive, not recruiting | Library tests named
|
| NCT07143734 | Start2025 | PhasePhase 2 | ConditionsDementia and Alzheimer's | Participants40 | Lead sponsorOther | StatusRecruiting | Library tests named
|
| NCT07064226 | Start2025 | PhaseNot applicable | ConditionsDementia and Alzheimer's, Mild cognitive impairment | Participants102 | Lead sponsorOther | StatusRecruiting | Library tests named
|
| NCT07036328 | Start2025 | PhaseNot applicable | ConditionsDementia and Alzheimer's | Participants55 | Lead sponsorOther | StatusRecruiting | Library tests named
|
| NCT07033481 | Start2025 | PhasePhase 2 | ConditionsDementia and Alzheimer's | Participants20 | Lead sponsorIndustry | StatusActive, not recruiting | Library tests named
|
| NCT07031167 | Start2025 | PhaseNot applicable | ConditionsDementia and Alzheimer's, Mild cognitive impairment | Participants100 | Lead sponsorOther | StatusNot yet recruiting | Library tests named
|
| NCT06953167 | Start2025 | PhaseObservational | ConditionsDementia and Alzheimer's | Participants600 | Lead sponsorOther | StatusRecruiting | Library tests named
|
| NCT06861231 | Start2024 | PhaseNot applicable | ConditionsDementia and Alzheimer's | Participants22 | Lead sponsorOther | StatusCompleted | Library tests named
|
| NCT06832761 | Start2025 | PhaseNot applicable | ConditionsDementia and Alzheimer's | Participants300 | Lead sponsorOther | StatusRecruiting | Library tests named
|
Questions, answered from the data
How many dementia and Alzheimer's trials use Category Fluency?
167 registered dementia and Alzheimer's disease studies on ClinicalTrials.gov name it in an outcome measure, 50 of them in a primary outcome: 10% of the condition's 1,673 studies with a cognitive outcome, against 4% of all of them. It is the 5th most named test in dementia and Alzheimer's trials.
Which tests do dementia and Alzheimer's trials use with Category Fluency?
Verbal Fluency (93 studies), the Trail Making Test (71 studies) and the Digit Span Test (65 studies).
How many participants do phase 2 dementia and Alzheimer's trials that use Category Fluency enroll?
Half of the phase 2 studies that name it enroll 89 participants or fewer, and the middle half enroll 42 to 162. 48 of them give a size.
When do dementia and Alzheimer's trials measure Category Fluency?
Half of the primary outcomes that name Category Fluency are measured within 6 months of the start, and the middle half from 12 weeks to 18 months. 45 primary outcomes give a duration.
How many completed dementia and Alzheimer's trials that use Category Fluency have reported results?
56 of the 81 completed studies that name it, 69%, have reported results: 38 posted them on ClinicalTrials.gov, 46 have a results paper linked to the registry record, and 28 did both. The other 25 show neither. Of all completed studies with a cognitive outcome, 46% have reported results.
How the studies are counted
For each test family, the census runs ClinicalTrials.gov's own outcome search for the family's names and reads every study first posted by the day the family was counted. These studies were read on 10 November 2026. A study counts once on a page, however many tests it names. Counts for a test cover every version of the task under any of its names, so a page can count studies that used a commercial version.
The census adds two things to each record and changes nothing in it: which outcome list names the test (primary, then secondary, then other), and the condition groups, matched on the study's condition names and MeSH terms. A study can fall in several groups; one whose only condition is cognitive impairment or decline falls in “Cognitive impairment and decline”. Studies that name only instruments outside the library count in every total and share but are not listed.
A second read on 10 November 2026 added each study's overall status, whether results are posted, its intervention types, the countries of its sites and the time frame of the outcome that names each test. A time frame counts by the latest time point it names: “Baseline, 12 and 24 weeks” is 24 weeks, a single visit is within a day, and one that names no duration, such as “end of treatment”, is left out of the timings.
A third read on 10 November 2026 added the papers the registry links to each study: those its sponsor lists as reporting results, and those PubMed links to it through the study's NCT number. A study has a results paper when one of them came out in or after the month of its primary completion and PubMed does not class it as a protocol, review or comment. A paper that never gives the NCT number is not linked, so some studies counted as reporting neither did publish.
Source: ClinicalTrials.gov, a database of the U.S. National Library of Medicine, which does not endorse these pages. Every study line is in the data release 2.1.0, and the explorer's own file is clinical-trials-studies.json.
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