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    16,361Registered studies name a cognitive test in an outcome measure11,688 name a test you can run hereExplore the studies
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  1. Home
  2. /Data
  3. /Clinical trials
  4. /Conditions
  5. /Mild cognitive impairment
  6. /Category Fluency

Clinical trials data

Category Fluency in mild cognitive impairment trials: 92 registered studies

Every registered mild cognitive impairment study on ClinicalTrials.gov that names Category Fluency in an outcome measure: how often it is a primary outcome, the tests named with it, how large the studies are and when they measure it.

Registered mild cognitive impairment studies name it in an outcome measure
92
Name it in a primary outcome, 42%
39 of 92
Of the condition's 859 studies name it, against 4% of all registered studies
11%
Other conditions
Median participants per study
69
By phase
Try Category Fluency

Tests named in the same studies

The library tests that mild cognitive impairment studies naming Category Fluency name most often beside it.
  1. 1

    Trail Making Test51 studies, 24 as a primary outcome

  2. 2

    Verbal Fluency48 studies, 19 as a primary outcome

  3. 3

    Digit Span Test39 studies, 17 as a primary outcome

  4. 4

    Verbal Learning36 studies, 23 as a primary outcome

  5. 5

    Symbol Coding26 studies, 15 as a primary outcome

  6. 6

    Short Story Recall26 studies, 13 as a primary outcome

  7. 7

    Picture Naming Test24 studies, 7 as a primary outcome

  8. 8

    Stroop Color-Word Test15 studies, 5 as a primary outcome

  9. 9

    Clock Drawing Task12 studies, 6 as a primary outcome

  10. 10

    Selective Reminding Task12 studies, 3 as a primary outcome

A test as a primary outcomeOnly in secondary or other outcomes

Studies by start year

Each study counted once. 2026 is partly planned starts.
02000: 0 studies, 0 with a test as a primary outcome20002001: 0 studies, 0 with a test as a primary outcome2002: 0 studies, 0 with a test as a primary outcome2003: 0 studies, 0 with a test as a primary outcome2004: 0 studies, 0 with a test as a primary outcome2005: 0 studies, 0 with a test as a primary outcome20052006: 0 studies, 0 with a test as a primary outcome2007: 0 studies, 0 with a test as a primary outcome2008: 2 studies, 1 with a test as a primary outcome2009: 0 studies, 0 with a test as a primary outcome2010: 0 studies, 0 with a test as a primary outcome20102011: 1 studies, 0 with a test as a primary outcome2012: 4 studies, 1 with a test as a primary outcome2013: 1 studies, 0 with a test as a primary outcome2014: 1 studies, 1 with a test as a primary outcome2015: 2 studies, 2 with a test as a primary outcome20152016: 6 studies, 2 with a test as a primary outcome2017: 4 studies, 3 with a test as a primary outcome2018: 2 studies, 1 with a test as a primary outcome2019: 4 studies, 3 with a test as a primary outcome2020: 9 studies, 5 with a test as a primary outcome20202021: 10 studies, 5 with a test as a primary outcome2022: 5 studies, 1 with a test as a primary outcome2023: 10 studies, 4 with a test as a primary outcome2024: 12 studies, 5 with a test as a primary outcome2025: 10 studies, 2 with a test as a primary outcome20252026: 9 studies, 3 with a test as a primary outcome

A test as a primary outcomeOnly in secondary or other outcomes

Show as a table
Registered studies by start year
Start yearStudiesA test as a primary outcome
200000
200100
200200
200300
200400
200500
200600
200700
200821
200900
201000
201110
201241
201310
201411
201522
201662
201743
201821
201943
202095
2021105
202251
2023104
2024125
2025102
202693

Phases and study sizes

By phase

  • Early phase 12 studies, 1 as a primary outcome
  • Phase 14 studies, 1 as a primary outcome
  • Phase 219 studies, 7 as a primary outcome
  • Phase 32 studies, 1 as a primary outcome
  • Not applicable58 studies, 27 as a primary outcome
  • Observational7 studies, 2 as a primary outcome

Participants per study

102050100200
  • Phase 288 median, 77 to 186
  • Not applicable60 median, 39 to 100
Participants per study. The bar spans the middle half of the studies in each phase, the mark is the median, and the axis is logarithmic. Phases with fewer than 10 studies that give a size are left out.
Show as a table
Participants per mild cognitive impairment study that names Category Fluency, by phase
PhaseStudies with a sizeMedianMiddle half
Phase 2178877 to 186
Not applicable586039 to 100

When mild cognitive impairment trials measure it

Half of the primary outcomes that name Category Fluency are measured within 6 months of the start, and the middle half from 13 weeks to 12 months. 35 primary outcomes give a duration.

Latest time point of each outcome

  • Within a day3 outcomes, 1 as a primary outcome
  • Up to 4 weeks5 outcomes, 1 as a primary outcome
  • 1 to 3 months20 outcomes, 9 as a primary outcome
  • 3 to 6 months29 outcomes, 13 as a primary outcome
  • 6 to 12 months13 outcomes, 3 as a primary outcome
  • 1 to 2 years12 outcomes, 7 as a primary outcome
  • Over 2 years6 outcomes, 1 as a primary outcome
  • No duration given4 outcomes, 4 as a primary outcome

A test as a primary outcomeOnly in secondary or other outcomes

88 of the 92 outcome measures give a duration. A single visit counts as within a day.

Status, results, interventions and countries

Status

  • Recruiting22 studies, 8 as a primary outcome
  • Not yet recruiting6 studies, 1 as a primary outcome
  • Active, not recruiting4 studies, 2 as a primary outcome
  • Completed36 studies, 15 as a primary outcome
  • Stopped early9 studies, 4 as a primary outcome
  • Status unknown15 studies, 9 as a primary outcome

What they test

  • Behavioral29 studies, 17 as a primary outcome
  • Drug20 studies, 5 as a primary outcome
  • Device24 studies, 8 as a primary outcome
  • Dietary supplement6 studies, 4 as a primary outcome
  • Procedure1 studies, 0 as a primary outcome
  • Diagnostic test1 studies, 1 as a primary outcome
  • Biological2 studies, 2 as a primary outcome
  • Radiation2 studies, 1 as a primary outcome
  • Combination product1 studies, 1 as a primary outcome
  • Other23 studies, 13 as a primary outcome
  • None given3 studies, 1 as a primary outcome

Intervention types as registered. A study can list several; observational studies often list none.

Where their sites are

  • United States37 studies, 21 as a primary outcome
  • Spain9 studies, 4 as a primary outcome
  • Italy8 studies, 1 as a primary outcome
  • Canada6 studies, 1 as a primary outcome
  • Germany5 studies, 1 as a primary outcome
  • Greece5 studies, 4 as a primary outcome
  • United Kingdom5 studies, 2 as a primary outcome
  • Taiwan4 studies, 1 as a primary outcome
  • Brazil3 studies, 0 as a primary outcome
  • China3 studies, 0 as a primary outcome
  • Singapore3 studies, 2 as a primary outcome
  • Australia2 studies, 1 as a primary outcome

37 countries in all. A study with sites in several counts in each; 7 list no site.

Reported results

Completed studies with results posted on ClinicalTrials.gov, a results paper the registry links to the study, or both.

Completed mild cognitive impairment studies that name Category Fluency: 22 of 36, 61%

Every completed study with a cognitive outcome: 3,626 of 7,953, 46%

Completed mild cognitive impairment studies that name Category Fluency and every completed study, by how they reported results
ResultsCompleted mild cognitive impairment studies that name Category FluencyEvery completed study
Results on ClinicalTrials.gov and a paper12, 33%776, 10%
Results on ClinicalTrials.gov only6, 17%1,139, 14%
A results paper only4, 11%1,711, 22%
Neither14, 39%4,327, 54%

The 92 studies

Filter by phase, sponsor, status, country, intervention, outcome list, size and start year. Each study links to its record on ClinicalTrials.gov.
ConditionMild cognitive impairment
TestCategory Fluency

92 studies match. 39 name Category Fluency in a primary outcome. Median size 69 participants. Median time to the primary outcome: 6 months.

Loading 92 studies; the filters turn on when they arrive.

By start year
0510152000: 0 studies, 0 naming Category Fluency in a primary outcome20002001: 0 studies, 0 naming Category Fluency in a primary outcome2002: 0 studies, 0 naming Category Fluency in a primary outcome2003: 0 studies, 0 naming Category Fluency in a primary outcome2004: 0 studies, 0 naming Category Fluency in a primary outcome2005: 0 studies, 0 naming Category Fluency in a primary outcome20052006: 0 studies, 0 naming Category Fluency in a primary outcome2007: 0 studies, 0 naming Category Fluency in a primary outcome2008: 2 studies, 1 naming Category Fluency in a primary outcome2009: 0 studies, 0 naming Category Fluency in a primary outcome2010: 0 studies, 0 naming Category Fluency in a primary outcome20102011: 1 studies, 0 naming Category Fluency in a primary outcome2012: 4 studies, 1 naming Category Fluency in a primary outcome2013: 1 studies, 0 naming Category Fluency in a primary outcome2014: 1 studies, 1 naming Category Fluency in a primary outcome2015: 2 studies, 2 naming Category Fluency in a primary outcome20152016: 6 studies, 2 naming Category Fluency in a primary outcome2017: 4 studies, 3 naming Category Fluency in a primary outcome2018: 2 studies, 1 naming Category Fluency in a primary outcome2019: 4 studies, 3 naming Category Fluency in a primary outcome2020: 9 studies, 5 naming Category Fluency in a primary outcome20202021: 10 studies, 5 naming Category Fluency in a primary outcome2022: 5 studies, 1 naming Category Fluency in a primary outcome2023: 10 studies, 4 naming Category Fluency in a primary outcome2024: 12 studies, 5 naming Category Fluency in a primary outcome2025: 10 studies, 2 naming Category Fluency in a primary outcome20252026: 9 studies, 3 naming Category Fluency in a primary outcome

2026 is partly planned starts.

Show as a table
Matching studies by start year
Start yearStudiesAs a primary outcome
200000
200100
200200
200300
200400
200500
200600
200700
200821
200900
201000
201110
201241
201310
201411
201522
201662
201743
201821
201943
202095
2021105
202251
2023104
2024125
2025102
202693

Library tests named most

  • Category Fluency92 studies, 39 as a primary outcome
  • Trail Making Test51 studies, 24 as a primary outcome
  • Verbal Fluency48 studies, 19 as a primary outcome
  • Digit Span Test39 studies, 17 as a primary outcome
  • Verbal Learning36 studies, 23 as a primary outcome
  • Symbol Coding26 studies, 15 as a primary outcome
  • Short Story Recall26 studies, 13 as a primary outcome
  • Picture Naming Test24 studies, 7 as a primary outcome
  • Stroop Color-Word Test15 studies, 5 as a primary outcome
  • Clock Drawing Task12 studies, 6 as a primary outcome

Largest condition groups

  • Mild cognitive impairment92 studies, 39 as a primary outcome
  • Dementia and Alzheimer's42 studies, 11 as a primary outcome
  • Aging, frailty and exercise8 studies, 4 as a primary outcome
  • Obesity and diabetes7 studies, 4 as a primary outcome
  • Parkinson's disease4 studies, 1 as a primary outcome
  • Cancer3 studies, 0 as a primary outcome
  • Cardiovascular disease3 studies, 3 as a primary outcome
  • Depression and bipolar disorder2 studies, 0 as a primary outcome
  • Sleep and sleep disorders2 studies, 1 as a primary outcome
  • Hearing loss2 studies, 2 as a primary outcome
  • Brain injury and concussion1 study, 0 as a primary outcome
  • Multiple sclerosis1 study, 0 as a primary outcome

Phases

Participants

Lead sponsor: industry 8, NIH 1, other 83. Interventional 85, observational 7.

As a primary outcomeSecondary or other outcomeCategory Fluency

The studies, newest registration first

Each number opens the study's record on ClinicalTrials.gov.

Registered studies that match the filters, newest registration first, with the library tests each one names and the outcome list that names them.
StudyStartPhaseConditionsParticipantsLead sponsorStatusLibrary tests named, with the latest time point
NCT07842146Start2026PhaseNot applicableConditionsDementia and Alzheimer's, Mild cognitive impairmentParticipants60Lead sponsorOtherStatusRecruitingLibrary tests named
  • Verbal FluencySecondary11 months
  • Symbol CodingSecondary11 months
  • Category FluencySecondary11 months
  • Delayed Recall ModuleSecondary11 months
NCT07786116Start2025PhaseNot applicableConditionsDementia and Alzheimer's, Mild cognitive impairment, Parkinson's disease, Sleep and sleep disordersParticipants215Lead sponsorOtherStatusRecruitingLibrary tests named
  • Category FluencyOther outcome18 months
NCT07651085Start2024PhaseObservationalConditionsDementia and Alzheimer's, Mild cognitive impairment, Parkinson's disease, Sleep and sleep disordersParticipants65Lead sponsorOtherStatusActive, not recruitingLibrary tests named
  • Verbal LearningPrimary
  • Verbal FluencyPrimary
  • Category FluencyPrimary
  • Clock Drawing TaskPrimary
NCT07650318Start2026PhaseNot applicableConditionsMild cognitive impairment, Obesity and diabetesParticipants40Lead sponsorOtherStatusRecruitingLibrary tests named
  • Digit Span TestSecondary6 months
  • Category FluencySecondary6 months
  • Picture Naming TestSecondary6 months
  • Short Story RecallSecondary6 months
  • Delayed Recall ModuleSecondary6 months
NCT07642518Start2026PhaseNot applicableConditionsMild cognitive impairment, Obesity and diabetesParticipants38Lead sponsorOtherStatusNot yet recruitingLibrary tests named
  • Trail Making TestSecondary6 months
  • Stroop Color-Word TestSecondary6 months
  • Digit Span TestSecondary6 months
  • Category FluencySecondary6 months
  • Picture Naming TestSecondary6 months
  • Short Story RecallSecondary6 months
NCT07526740Start2026PhaseNot applicableConditionsMild cognitive impairmentParticipants50Lead sponsorOtherStatusRecruitingLibrary tests named
  • Category FluencyPrimary6 weeks
NCT07423260Start2026PhaseNot applicableConditionsMild cognitive impairmentParticipants38Lead sponsorOtherStatusNot yet recruitingLibrary tests named
  • Trail Making TestPrimary16 weeks
  • Category FluencyPrimary16 weeks
  • Arithmetic Fluency TaskPrimary16 weeks
NCT07402356Start2025PhaseObservationalConditionsDementia and Alzheimer's, Mild cognitive impairment, Depression and bipolar disorderParticipants140Lead sponsorOtherStatusRecruitingLibrary tests named
  • Trail Making TestSecondary6 months
  • Verbal LearningSecondary6 months
  • Verbal FluencySecondary6 months
  • N-Back TaskPrimarysame day
  • Category FluencySecondary6 months
  • Picture Naming TestSecondary6 months
NCT07389655Start2026PhaseNot applicableConditionsMild cognitive impairmentParticipants30Lead sponsorOtherStatusNot yet recruitingLibrary tests named
  • Digit Span TestSecondary12 weeks
  • Category FluencySecondary12 weeks
  • Short Story RecallSecondary12 weeks
NCT07385937Start2026PhaseNot applicableConditionsDementia and Alzheimer's, Mild cognitive impairmentParticipants150Lead sponsorOtherStatusNot yet recruitingLibrary tests named
  • Trail Making TestSecondary18 months
  • Verbal FluencySecondary18 months
  • Digit Span TestSecondary18 months
  • Category FluencySecondary18 months
  • Clock Drawing TaskSecondary18 months
  • Cancellation TestSecondary18 months
  • Delayed Recall ModuleSecondary18 months
NCT07366346Start2026PhaseNot applicableConditionsDementia and Alzheimer's, Mild cognitive impairmentParticipants100Lead sponsorOtherStatusRecruitingLibrary tests named
  • Trail Making TestPrimary5 months
  • Verbal LearningPrimary5 months
  • Verbal FluencyPrimary5 months
  • Category FluencyPrimary5 months
NCT07241598Start2025PhaseNot applicableConditionsDementia and Alzheimer's, Mild cognitive impairmentParticipants70Lead sponsorOtherStatusNot yet recruitingLibrary tests named
  • Trail Making TestSecondary12 months
  • Verbal FluencySecondary12 months
  • Digit Span TestSecondary12 months
  • Symbol CodingSecondary12 months
  • Go/No-Go TaskSecondary12 months
  • Category FluencySecondary12 months
NCT07210528Start2025PhasePhase 1ConditionsDementia and Alzheimer's, Mild cognitive impairmentParticipants48Lead sponsorOtherStatusActive, not recruitingLibrary tests named
  • Digit Span TestSecondary12 weeks
  • Category FluencySecondary12 weeks
  • Picture Naming TestSecondary12 weeks
  • Short Story RecallSecondary12 weeks
NCT07064226Start2025PhaseNot applicableConditionsDementia and Alzheimer's, Mild cognitive impairmentParticipants102Lead sponsorOtherStatusRecruitingLibrary tests named
  • Trail Making TestSecondary6 months
  • Verbal FluencySecondary6 months
  • Category FluencySecondary6 months
  • Selective Reminding TaskSecondary6 months
NCT07031167Start2025PhaseNot applicableConditionsDementia and Alzheimer's, Mild cognitive impairmentParticipants100Lead sponsorOtherStatusNot yet recruitingLibrary tests named
  • Category FluencyOther outcome2 years
NCT06828926Start2025PhaseNot applicableConditionsMild cognitive impairment, Aging, frailty and exerciseParticipants50Lead sponsorOtherStatusRecruitingLibrary tests named
  • Stroop Color-Word TestPrimary8 weeks
  • Category FluencyPrimary8 weeks
NCT06825403Start2025PhaseNot applicableConditionsMild cognitive impairmentParticipants30Lead sponsorOtherStatusRecruitingLibrary tests named
  • Symbol CodingPrimary6 months
  • Category FluencyPrimary6 months
  • Short Story RecallPrimary6 months
  • Selective Reminding TaskPrimary6 months
NCT06734286Start2024PhaseNot applicableConditionsMild cognitive impairmentParticipants10Lead sponsorOtherStatusRecruitingLibrary tests named
  • Trail Making TestPrimary13 weeks
  • Verbal LearningSecondary13 weeks
  • Digit Span TestPrimary13 weeks
  • Category FluencyPrimary13 weeks
NCT06733714Start2024PhaseNot applicableConditionsDementia and Alzheimer's, Mild cognitive impairmentParticipants40Lead sponsorOtherStatusRecruitingLibrary tests named
  • Verbal LearningSecondary1 week
  • Verbal FluencySecondary1 week
  • Category FluencySecondary1 week
  • Complex Figure Copy and RecallSecondary1 week
  • Oddball Target DetectionSecondary1 week
  • Antisaccade TaskSecondary1 week
  • Visual Search TestSecondary1 week
NCT06705478Start2026PhasePhase 2ConditionsMild cognitive impairment, Depression and bipolar disorderParticipants186Lead sponsorNIHStatusStopped earlyLibrary tests named
  • Category FluencySecondary6 months
NCT06657274Start2024PhaseNot applicableConditionsMild cognitive impairment, Parkinson's diseaseParticipants60Lead sponsorOtherStatusRecruitingLibrary tests named
  • Stroop Color-Word TestSecondary13 weeks
  • Verbal FluencySecondary13 weeks
  • Category FluencySecondary13 weeks
  • Complex Figure Copy and RecallSecondary13 weeks
  • Matrix ReasoningSecondary13 weeks
  • Selective Reminding TaskPrimary13 weeks
  • Delayed Recall ModulePrimary13 weeks
NCT06601933Start2024PhasePhase 2ConditionsMild cognitive impairmentParticipants240Lead sponsorOtherStatusRecruitingLibrary tests named
  • Symbol CodingOther outcome18 months
  • Category FluencyOther outcome18 months
  • Short Story RecallOther outcome18 months
  • Selective Reminding TaskOther outcome18 months
NCT06467539Start2024PhasePhase 2ConditionsDementia and Alzheimer's, Mild cognitive impairmentParticipants80Lead sponsorOtherStatusRecruitingLibrary tests named
  • Category FluencySecondary6 months
NCT06281652Start2024PhaseNot applicableConditionsMild cognitive impairmentParticipants80Lead sponsorOtherStatusCompletedLibrary tests named
  • Trail Making TestSecondary12 weeks
  • Digit Span TestSecondary12 weeks
  • Category FluencySecondary12 weeks
NCT06246929Start2025PhaseNot applicableConditionsMild cognitive impairment, Aging, frailty and exercise, Pain and fatigueParticipants400Lead sponsorOtherStatusRecruitingLibrary tests named
  • Category FluencySecondary6 months
  • Clock Drawing TaskSecondary6 months

Page 1 of 4

Questions, answered from the data

How many mild cognitive impairment trials use Category Fluency?

92 registered mild cognitive impairment studies on ClinicalTrials.gov name it in an outcome measure, 39 of them in a primary outcome: 11% of the condition's 859 studies with a cognitive outcome, against 4% of all of them. It is the 6th most named test in mild cognitive impairment trials.

Which tests do mild cognitive impairment trials use with Category Fluency?

The Trail Making Test (51 studies), Verbal Fluency (48 studies) and the Digit Span Test (39 studies).

How many participants do phase 2 mild cognitive impairment trials that use Category Fluency enroll?

Half of the phase 2 studies that name it enroll 88 participants or fewer, and the middle half enroll 77 to 186. 17 of them give a size.

When do mild cognitive impairment trials measure Category Fluency?

Half of the primary outcomes that name Category Fluency are measured within 6 months of the start, and the middle half from 13 weeks to 12 months. 35 primary outcomes give a duration.

How many completed mild cognitive impairment trials that use Category Fluency have reported results?

22 of the 36 completed studies that name it, 61%, have reported results: 18 posted them on ClinicalTrials.gov, 16 have a results paper linked to the registry record, and 12 did both. The other 14 show neither. Of all completed studies with a cognitive outcome, 46% have reported results.

More on Category Fluency and mild cognitive impairment

  • Every cognitive test in mild cognitive impairment trials: 859 studies
  • Category Fluency in all clinical trials: 623 studies

Category Fluency in other conditions

  • Dementia and Alzheimer's167

Other tests in mild cognitive impairment trials

  • Trail Making Test213
  • Verbal Learning183
  • Verbal Fluency177
  • Digit Span Test169
  • Stroop Color-Word Test126
  • Symbol Coding84
  • Short Story Recall74
  • Picture Naming Test71

How the studies are counted

For each test family, the census runs ClinicalTrials.gov's own outcome search for the family's names and reads every study first posted by the day the family was counted. These studies were read on 10 November 2026. A study counts once on a page, however many tests it names. Counts for a test cover every version of the task under any of its names, so a page can count studies that used a commercial version.

The census adds two things to each record and changes nothing in it: which outcome list names the test (primary, then secondary, then other), and the condition groups, matched on the study's condition names and MeSH terms. A study can fall in several groups; one whose only condition is cognitive impairment or decline falls in “Cognitive impairment and decline”. Studies that name only instruments outside the library count in every total and share but are not listed.

A second read on 10 November 2026 added each study's overall status, whether results are posted, its intervention types, the countries of its sites and the time frame of the outcome that names each test. A time frame counts by the latest time point it names: “Baseline, 12 and 24 weeks” is 24 weeks, a single visit is within a day, and one that names no duration, such as “end of treatment”, is left out of the timings.

A third read on 10 November 2026 added the papers the registry links to each study: those its sponsor lists as reporting results, and those PubMed links to it through the study's NCT number. A study has a results paper when one of them came out in or after the month of its primary completion and PubMed does not class it as a protocol, review or comment. A paper that never gives the NCT number is not linked, so some studies counted as reporting neither did publish.

Source: ClinicalTrials.gov, a database of the U.S. National Library of Medicine, which does not endorse these pages. Every study line is in the data release 2.1.0, and the explorer's own file is clinical-trials-studies.json.

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