Clinical trials data
Verbal Fluency in cancer trials: 200 registered studies
Every registered cancer study on ClinicalTrials.gov that names Verbal Fluency in an outcome measure: how often it is a primary outcome, the tests named with it, how large the studies are and when they measure it.
- Registered cancer studies name it in an outcome measure
- 200
- Name it in a primary outcome, 32%
- 64 of 200
Tests named in the same studies
- 1
Verbal Learning136 studies, 49 as a primary outcome
- 2
Trail Making Test119 studies, 36 as a primary outcome
- 3
Digit Span Test62 studies, 22 as a primary outcome
- 4
Symbol Coding26 studies, 14 as a primary outcome
- 5
Stroop Color-Word Test24 studies, 10 as a primary outcome
- 6
Category Fluency20 studies, 5 as a primary outcome
- 7
Paced Visual Serial Addition Test10 studies, 6 as a primary outcome
- 8
Task Switching Test10 studies, 3 as a primary outcome
- 9
Continuous Performance Test9 studies, 4 as a primary outcome
- 10
Picture Naming Test9 studies, 4 as a primary outcome
A test as a primary outcomeOnly in secondary or other outcomes
Studies by start year
A test as a primary outcomeOnly in secondary or other outcomes
Show as a table
| Start year | Studies | A test as a primary outcome |
|---|---|---|
| 2000 | 0 | 0 |
| 2001 | 1 | 0 |
| 2002 | 0 | 0 |
| 2003 | 0 | 0 |
| 2004 | 2 | 1 |
| 2005 | 2 | 2 |
| 2006 | 2 | 1 |
| 2007 | 3 | 0 |
| 2008 | 2 | 0 |
| 2009 | 3 | 0 |
| 2010 | 1 | 1 |
| 2011 | 3 | 1 |
| 2012 | 1 | 1 |
| 2013 | 7 | 3 |
| 2014 | 7 | 2 |
| 2015 | 12 | 6 |
| 2016 | 8 | 0 |
| 2017 | 13 | 3 |
| 2018 | 11 | 3 |
| 2019 | 11 | 5 |
| 2020 | 9 | 4 |
| 2021 | 21 | 6 |
| 2022 | 14 | 7 |
| 2023 | 16 | 4 |
| 2024 | 18 | 3 |
| 2025 | 10 | 3 |
| 2026 | 22 | 8 |
Phases and study sizes
By phase
- Early phase 13 studies, 1 as a primary outcome
- Phase 12 studies, 0 as a primary outcome
- Phase 1/26 studies, 2 as a primary outcome
- Phase 233 studies, 6 as a primary outcome
- Phase 2/31 studies, 0 as a primary outcome
- Phase 322 studies, 5 as a primary outcome
- Phase 43 studies, 2 as a primary outcome
- Not applicable87 studies, 30 as a primary outcome
- Observational43 studies, 18 as a primary outcome
Participants per study
- Phase 274 median, 43 to 111
- Phase 3318 median, 179 to 501
- Not applicable74 median, 42 to 134
- Observational100 median, 48 to 203
Show as a table
| Phase | Studies with a size | Median | Middle half |
|---|---|---|---|
| Phase 2 | 32 | 74 | 43 to 111 |
| Phase 3 | 22 | 318 | 179 to 501 |
| Not applicable | 84 | 74 | 42 to 134 |
| Observational | 43 | 100 | 48 to 203 |
When cancer trials measure it
Latest time point of each outcome
- Within a day15 outcomes, 6 as a primary outcome
- Up to 4 weeks11 outcomes, 4 as a primary outcome
- 1 to 3 months30 outcomes, 13 as a primary outcome
- 3 to 6 months44 outcomes, 14 as a primary outcome
- 6 to 12 months51 outcomes, 13 as a primary outcome
- 1 to 2 years24 outcomes, 8 as a primary outcome
- Over 2 years21 outcomes, 4 as a primary outcome
- No duration given4 outcomes, 2 as a primary outcome
A test as a primary outcomeOnly in secondary or other outcomes
196 of the 200 outcome measures give a duration. A single visit counts as within a day.
Status, results, interventions and countries
Status
- Recruiting55 studies, 19 as a primary outcome
- Not yet recruiting14 studies, 6 as a primary outcome
- Active, not recruiting27 studies, 5 as a primary outcome
- Completed60 studies, 19 as a primary outcome
- Stopped early18 studies, 7 as a primary outcome
- Status unknown26 studies, 8 as a primary outcome
What they test
- Behavioral45 studies, 18 as a primary outcome
- Drug58 studies, 14 as a primary outcome
- Device18 studies, 4 as a primary outcome
- Dietary supplement1 studies, 1 as a primary outcome
- Procedure17 studies, 6 as a primary outcome
- Diagnostic test5 studies, 2 as a primary outcome
- Biological6 studies, 0 as a primary outcome
- Radiation55 studies, 16 as a primary outcome
- Combination product1 studies, 0 as a primary outcome
- Other56 studies, 15 as a primary outcome
- None given16 studies, 7 as a primary outcome
Intervention types as registered. A study can list several; observational studies often list none.
Where their sites are
- United States104 studies, 34 as a primary outcome
- Canada28 studies, 4 as a primary outcome
- Spain15 studies, 6 as a primary outcome
- Netherlands13 studies, 3 as a primary outcome
- France12 studies, 2 as a primary outcome
- Italy10 studies, 4 as a primary outcome
- Denmark8 studies, 2 as a primary outcome
- Germany8 studies, 0 as a primary outcome
- China5 studies, 0 as a primary outcome
- Israel5 studies, 0 as a primary outcome
- Australia4 studies, 0 as a primary outcome
- Austria4 studies, 0 as a primary outcome
39 countries in all. A study with sites in several counts in each; 6 list no site.
Reported results
Completed studies with results posted on ClinicalTrials.gov, a results paper the registry links to the study, or both.
Completed cancer studies that name Verbal Fluency: 38 of 60, 63%
Every completed study with a cognitive outcome: 3,626 of 7,953, 46%
| Results | Completed cancer studies that name Verbal Fluency | Every completed study |
|---|---|---|
| Results on ClinicalTrials.gov and a paper | 13, 22% | 776, 10% |
| Results on ClinicalTrials.gov only | 14, 23% | 1,139, 14% |
| A results paper only | 11, 18% | 1,711, 22% |
| Neither | 22, 37% | 4,327, 54% |
The 200 studies
200 studies match. 64 name Verbal Fluency in a primary outcome. Median size 84 participants. Median time to the primary outcome: 4 months.
Loading 200 studies; the filters turn on when they arrive.
2026 is partly planned starts. Not shown: 1 planned to start after 2026.
Show as a table
| Start year | Studies | As a primary outcome |
|---|---|---|
| 2000 | 0 | 0 |
| 2001 | 1 | 0 |
| 2002 | 0 | 0 |
| 2003 | 0 | 0 |
| 2004 | 2 | 1 |
| 2005 | 2 | 2 |
| 2006 | 2 | 1 |
| 2007 | 3 | 0 |
| 2008 | 2 | 0 |
| 2009 | 3 | 0 |
| 2010 | 1 | 1 |
| 2011 | 3 | 1 |
| 2012 | 1 | 1 |
| 2013 | 7 | 3 |
| 2014 | 7 | 2 |
| 2015 | 12 | 6 |
| 2016 | 8 | 0 |
| 2017 | 13 | 3 |
| 2018 | 11 | 3 |
| 2019 | 11 | 5 |
| 2020 | 9 | 4 |
| 2021 | 21 | 6 |
| 2022 | 14 | 7 |
| 2023 | 16 | 4 |
| 2024 | 18 | 3 |
| 2025 | 10 | 3 |
| 2026 | 22 | 8 |
Library tests named most
Largest condition groups
Phases
Participants
Lead sponsor: industry 9, NIH 1, other 190. Interventional 157, observational 43.
As a primary outcomeSecondary or other outcomeVerbal Fluency
The studies, newest registration first
Each number opens the study's record on ClinicalTrials.gov.
| Study | Start | Phase | Conditions | Participants | Lead sponsor | Status | Library tests named, with the latest time point |
|---|---|---|---|---|---|---|---|
| NCT07908147 | Start2027 | PhaseEarly phase 1 | ConditionsCancer | Participants12 | Lead sponsorOther | StatusNot yet recruiting | Library tests named
|
| NCT07867886 | Start2026 | PhaseNot applicable | ConditionsCancer | Participants30 | Lead sponsorIndustry | StatusNot yet recruiting | Library tests named
|
| NCT07755839 | Start2026 | PhaseNot applicable | ConditionsDepression and bipolar disorder, Cancer, Anxiety, PTSD and OCD | Participants60 | Lead sponsorOther | StatusNot yet recruiting | Library tests named
|
| NCT07740317 | Start2026 | PhaseObservational | ConditionsCancer | Participants50 | Lead sponsorOther | StatusRecruiting | Library tests named
|
| NCT07729969 | Start2026 | PhaseNot applicable | ConditionsCancer | Participants110 | Lead sponsorOther | StatusRecruiting | Library tests named
|
| NCT07716800 | Start2026 | PhaseObservational | ConditionsCancer, Delirium, surgery and intensive care | Participants205 | Lead sponsorOther | StatusNot yet recruiting | Library tests named
|
| NCT07652476 | Start2026 | PhaseObservational | ConditionsCancer | Participants100 | Lead sponsorOther | StatusNot yet recruiting | Library tests named
|
| NCT07638852 | Start2026 | PhasePhase 2 | ConditionsCancer | Participants58 | Lead sponsorOther | StatusRecruiting | Library tests named
|
| NCT07633626 | Start2026 | PhaseObservational | ConditionsDepression and bipolar disorder, Cancer | Participants24 | Lead sponsorOther | StatusRecruiting | Library tests named
|
| NCT07606313 | Start2026 | PhaseNot applicable | ConditionsCancer | Participants150 | Lead sponsorOther | StatusNot yet recruiting | Library tests named
|
| NCT07479927 | Start2025 | PhaseNot applicable | ConditionsCancer | Participants40 | Lead sponsorOther | StatusRecruiting | Library tests named
|
| NCT07470606 | Start2026 | PhasePhase 2 | ConditionsCancer | Participants108 | Lead sponsorOther | StatusRecruiting | Library tests named
|
| NCT07463781 | Start2026 | PhaseObservational | ConditionsCancer | Participants100 | Lead sponsorOther | StatusNot yet recruiting | Library tests named
|
| NCT07452458 | Start2026 | PhasePhase 3 | ConditionsCancer | Participants398 | Lead sponsorOther | StatusRecruiting | Library tests named
|
| NCT07383649 | Start2026 | PhasePhase 2 | ConditionsCancer | Participants28 | Lead sponsorOther | StatusRecruiting | Library tests named
|
| NCT07313709 | Start2026 | PhaseNot applicable | ConditionsCancer | Participants40 | Lead sponsorOther | StatusNot yet recruiting | Library tests named
|
| NCT07292272 | Start2026 | PhaseNot applicable | ConditionsCancer | Participants180 | Lead sponsorOther | StatusRecruiting | Library tests named
|
| NCT07259434 | Start2026 | PhaseNot applicable | ConditionsCancer, Cardiovascular disease | Participants152 | Lead sponsorOther | StatusNot yet recruiting | Library tests named
|
| NCT07248228 | Start2026 | PhasePhase 2 | ConditionsCancer | Participants90 | Lead sponsorOther | StatusRecruiting | Library tests named
|
| NCT07224503 | Start2025 | PhaseNot applicable | ConditionsCancer | Participants56 | Lead sponsorOther | StatusRecruiting | Library tests named
|
| NCT07165912 | Start2026 | PhaseNot applicable | ConditionsCancer | Participants75 | Lead sponsorOther | StatusNot yet recruiting | Library tests named
|
| NCT07160751 | Start2026 | PhaseObservational | ConditionsCancer | Participants90 | Lead sponsorOther | StatusRecruiting | Library tests named
|
| NCT07147621 | Start2026 | PhaseObservational | ConditionsCancer | Participants120 | Lead sponsorOther | StatusRecruiting | Library tests named
|
| NCT07125209 | Start2026 | PhaseObservational | ConditionsCancer | Participants18 | Lead sponsorOther | StatusRecruiting | Library tests named
|
| NCT07046936 | Start2026 | PhaseObservational | ConditionsCancer | Participants30 | Lead sponsorOther | StatusRecruiting | Library tests named
|
Questions, answered from the data
How many cancer trials use Verbal Fluency?
200 registered cancer studies on ClinicalTrials.gov name it in an outcome measure, 64 of them in a primary outcome: 26% of the condition's 760 studies with a cognitive outcome, against 11% of all of them. It is the 2nd most named test in cancer trials.
Which tests do cancer trials use with Verbal Fluency?
Verbal Learning (136 studies), the Trail Making Test (119 studies) and the Digit Span Test (62 studies).
How many participants do phase 2 cancer trials that use Verbal Fluency enroll?
Half of the phase 2 studies that name it enroll 74 participants or fewer, and the middle half enroll 43 to 111. 32 of them give a size.
When do cancer trials measure Verbal Fluency?
Half of the primary outcomes that name Verbal Fluency are measured within 4 months of the start, and the middle half from 12 weeks to 12 months. 62 primary outcomes give a duration.
How many completed cancer trials that use Verbal Fluency have reported results?
38 of the 60 completed studies that name it, 63%, have reported results: 27 posted them on ClinicalTrials.gov, 24 have a results paper linked to the registry record, and 13 did both. The other 22 show neither. Of all completed studies with a cognitive outcome, 46% have reported results.
How the studies are counted
For each test family, the census runs ClinicalTrials.gov's own outcome search for the family's names and reads every study first posted by the day the family was counted. These studies were read on 10 November 2026. A study counts once on a page, however many tests it names. Counts for a test cover every version of the task under any of its names, so a page can count studies that used a commercial version.
The census adds two things to each record and changes nothing in it: which outcome list names the test (primary, then secondary, then other), and the condition groups, matched on the study's condition names and MeSH terms. A study can fall in several groups; one whose only condition is cognitive impairment or decline falls in “Cognitive impairment and decline”. Studies that name only instruments outside the library count in every total and share but are not listed.
A second read on 10 November 2026 added each study's overall status, whether results are posted, its intervention types, the countries of its sites and the time frame of the outcome that names each test. A time frame counts by the latest time point it names: “Baseline, 12 and 24 weeks” is 24 weeks, a single visit is within a day, and one that names no duration, such as “end of treatment”, is left out of the timings.
A third read on 10 November 2026 added the papers the registry links to each study: those its sponsor lists as reporting results, and those PubMed links to it through the study's NCT number. A study has a results paper when one of them came out in or after the month of its primary completion and PubMed does not class it as a protocol, review or comment. A paper that never gives the NCT number is not linked, so some studies counted as reporting neither did publish.
Source: ClinicalTrials.gov, a database of the U.S. National Library of Medicine, which does not endorse these pages. Every study line is in the data release 2.1.0, and the explorer's own file is clinical-trials-studies.json.
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