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    16,361Registered studies name a cognitive test in an outcome measure11,688 name a test you can run hereExplore the studies
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  1. Home
  2. /Data
  3. /Clinical trials
  4. /Conditions
  5. /Cancer
  6. /Symbol Coding

Clinical trials data

Symbol Coding in cancer trials: 58 registered studies

Every registered cancer study on ClinicalTrials.gov that names Symbol Coding in an outcome measure: how often it is a primary outcome, the tests named with it, how large the studies are and when they measure it.

Registered cancer studies name it in an outcome measure
58
Name it in a primary outcome, 47%
27 of 58
Of the condition's 760 studies name it, against 9% of all registered studies
8%
Other conditions
Median participants per study
82
By phase
Try the Symbol Key GameTry Symbol Coding

Tests named in the same studies

The library tests that cancer studies naming Symbol Coding name most often beside it.
  1. 1

    Verbal Learning32 studies, 15 as a primary outcome

  2. 2

    Digit Span Test27 studies, 14 as a primary outcome

  3. 3

    Trail Making Test27 studies, 13 as a primary outcome

  4. 4

    Verbal Fluency26 studies, 13 as a primary outcome

  5. 5

    Stroop Color-Word Test11 studies, 6 as a primary outcome

  6. 6

    Category Fluency6 studies, 2 as a primary outcome

  7. 7

    Paced Visual Serial Addition Test5 studies, 2 as a primary outcome

  8. 8

    Short Story Recall5 studies, 2 as a primary outcome

  9. 9

    Continuous Performance Test4 studies, 3 as a primary outcome

  10. 10

    Complex Figure Copy and Recall3 studies, 2 as a primary outcome

A test as a primary outcomeOnly in secondary or other outcomes

Studies by start year

Each study counted once. 2026 is partly planned starts.
02000: 0 studies, 0 with a test as a primary outcome20002001: 0 studies, 0 with a test as a primary outcome2002: 0 studies, 0 with a test as a primary outcome2003: 0 studies, 0 with a test as a primary outcome2004: 0 studies, 0 with a test as a primary outcome2005: 0 studies, 0 with a test as a primary outcome20052006: 0 studies, 0 with a test as a primary outcome2007: 0 studies, 0 with a test as a primary outcome2008: 1 studies, 0 with a test as a primary outcome2009: 1 studies, 1 with a test as a primary outcome2010: 1 studies, 1 with a test as a primary outcome20102011: 1 studies, 0 with a test as a primary outcome2012: 0 studies, 0 with a test as a primary outcome2013: 0 studies, 0 with a test as a primary outcome2014: 5 studies, 2 with a test as a primary outcome2015: 1 studies, 0 with a test as a primary outcome20152016: 1 studies, 0 with a test as a primary outcome2017: 4 studies, 1 with a test as a primary outcome2018: 2 studies, 2 with a test as a primary outcome2019: 2 studies, 0 with a test as a primary outcome2020: 2 studies, 1 with a test as a primary outcome20202021: 6 studies, 3 with a test as a primary outcome2022: 6 studies, 5 with a test as a primary outcome2023: 6 studies, 1 with a test as a primary outcome2024: 9 studies, 3 with a test as a primary outcome2025: 2 studies, 2 with a test as a primary outcome20252026: 7 studies, 5 with a test as a primary outcome

A test as a primary outcomeOnly in secondary or other outcomes

Show as a table
Registered studies by start year
Start yearStudiesA test as a primary outcome
200000
200100
200200
200300
200400
200500
200600
200700
200810
200911
201011
201110
201200
201300
201452
201510
201610
201741
201822
201920
202021
202163
202265
202361
202493
202522
202675

Phases and study sizes

By phase

  • Early phase 11 studies, 1 as a primary outcome
  • Phase 13 studies, 0 as a primary outcome
  • Phase 23 studies, 1 as a primary outcome
  • Phase 36 studies, 2 as a primary outcome
  • Phase 41 studies, 1 as a primary outcome
  • Not applicable27 studies, 10 as a primary outcome
  • Observational17 studies, 12 as a primary outcome

Participants per study

102050100200
  • Not applicable84 median, 41 to 145
  • Observational60 median, 40 to 100
Participants per study. The bar spans the middle half of the studies in each phase, the mark is the median, and the axis is logarithmic. Phases with fewer than 10 studies that give a size are left out.
Show as a table
Participants per cancer study that names Symbol Coding, by phase
PhaseStudies with a sizeMedianMiddle half
Not applicable278441 to 145
Observational176040 to 100

When cancer trials measure it

Half of the primary outcomes that name Symbol Coding are measured within 6 months of the start, and the middle half from 12 weeks to 12 months. 25 primary outcomes give a duration.

Latest time point of each outcome

  • Within a day5 outcomes, 2 as a primary outcome
  • Up to 4 weeks8 outcomes, 3 as a primary outcome
  • 1 to 3 months14 outcomes, 7 as a primary outcome
  • 3 to 6 months12 outcomes, 5 as a primary outcome
  • 6 to 12 months9 outcomes, 4 as a primary outcome
  • 1 to 2 years3 outcomes, 2 as a primary outcome
  • Over 2 years5 outcomes, 2 as a primary outcome
  • No duration given2 outcomes, 2 as a primary outcome

A test as a primary outcomeOnly in secondary or other outcomes

56 of the 58 outcome measures give a duration. A single visit counts as within a day.

Status, results, interventions and countries

Status

  • Recruiting12 studies, 8 as a primary outcome
  • Not yet recruiting5 studies, 3 as a primary outcome
  • Active, not recruiting7 studies, 3 as a primary outcome
  • Completed20 studies, 6 as a primary outcome
  • Stopped early6 studies, 2 as a primary outcome
  • Status unknown8 studies, 5 as a primary outcome

What they test

  • Behavioral22 studies, 10 as a primary outcome
  • Drug14 studies, 5 as a primary outcome
  • Device6 studies, 2 as a primary outcome
  • Dietary supplement2 studies, 2 as a primary outcome
  • Procedure1 studies, 0 as a primary outcome
  • Diagnostic test2 studies, 1 as a primary outcome
  • Radiation3 studies, 0 as a primary outcome
  • Other15 studies, 7 as a primary outcome
  • None given7 studies, 5 as a primary outcome

Intervention types as registered. A study can list several; observational studies often list none.

Where their sites are

  • United States24 studies, 8 as a primary outcome
  • Italy8 studies, 5 as a primary outcome
  • Canada7 studies, 2 as a primary outcome
  • France4 studies, 0 as a primary outcome
  • China3 studies, 2 as a primary outcome
  • Denmark3 studies, 1 as a primary outcome
  • Spain3 studies, 2 as a primary outcome
  • Belgium2 studies, 0 as a primary outcome
  • Germany2 studies, 0 as a primary outcome
  • Netherlands2 studies, 0 as a primary outcome
  • United Kingdom2 studies, 1 as a primary outcome
  • Australia1 studies, 1 as a primary outcome

22 countries in all. A study with sites in several counts in each; 4 list no site.

Reported results

Completed studies with results posted on ClinicalTrials.gov, a results paper the registry links to the study, or both.

Completed cancer studies that name Symbol Coding: 10 of 20, 50%

Every completed study with a cognitive outcome: 3,626 of 7,953, 46%

Completed cancer studies that name Symbol Coding and every completed study, by how they reported results
ResultsCompleted cancer studies that name Symbol CodingEvery completed study
Results on ClinicalTrials.gov and a paper3, 15%776, 10%
Results on ClinicalTrials.gov only3, 15%1,139, 14%
A results paper only4, 20%1,711, 22%
Neither10, 50%4,327, 54%

The 58 studies

Filter by phase, sponsor, status, country, intervention, outcome list, size and start year. Each study links to its record on ClinicalTrials.gov.
ConditionCancer
TestSymbol Coding

58 studies match. 27 name Symbol Coding in a primary outcome. Median size 82 participants. Median time to the primary outcome: 6 months.

Loading 58 studies; the filters turn on when they arrive.

By start year
02.557.5102000: 0 studies, 0 naming Symbol Coding in a primary outcome20002001: 0 studies, 0 naming Symbol Coding in a primary outcome2002: 0 studies, 0 naming Symbol Coding in a primary outcome2003: 0 studies, 0 naming Symbol Coding in a primary outcome2004: 0 studies, 0 naming Symbol Coding in a primary outcome2005: 0 studies, 0 naming Symbol Coding in a primary outcome20052006: 0 studies, 0 naming Symbol Coding in a primary outcome2007: 0 studies, 0 naming Symbol Coding in a primary outcome2008: 1 studies, 0 naming Symbol Coding in a primary outcome2009: 1 studies, 1 naming Symbol Coding in a primary outcome2010: 1 studies, 1 naming Symbol Coding in a primary outcome20102011: 1 studies, 0 naming Symbol Coding in a primary outcome2012: 0 studies, 0 naming Symbol Coding in a primary outcome2013: 0 studies, 0 naming Symbol Coding in a primary outcome2014: 5 studies, 2 naming Symbol Coding in a primary outcome2015: 1 studies, 0 naming Symbol Coding in a primary outcome20152016: 1 studies, 0 naming Symbol Coding in a primary outcome2017: 4 studies, 1 naming Symbol Coding in a primary outcome2018: 2 studies, 2 naming Symbol Coding in a primary outcome2019: 2 studies, 0 naming Symbol Coding in a primary outcome2020: 2 studies, 1 naming Symbol Coding in a primary outcome20202021: 6 studies, 3 naming Symbol Coding in a primary outcome2022: 6 studies, 5 naming Symbol Coding in a primary outcome2023: 6 studies, 1 naming Symbol Coding in a primary outcome2024: 9 studies, 3 naming Symbol Coding in a primary outcome2025: 2 studies, 2 naming Symbol Coding in a primary outcome20252026: 7 studies, 5 naming Symbol Coding in a primary outcome

2026 is partly planned starts. Not shown: 1 that started before 2000.

Show as a table
Matching studies by start year
Start yearStudiesAs a primary outcome
200000
200100
200200
200300
200400
200500
200600
200700
200810
200911
201011
201110
201200
201300
201452
201510
201610
201741
201822
201920
202021
202163
202265
202361
202493
202522
202675

Library tests named most

  • Symbol Coding58 studies, 27 as a primary outcome
  • Verbal Learning32 studies, 15 as a primary outcome
  • Digit Span Test27 studies, 14 as a primary outcome
  • Trail Making Test27 studies, 13 as a primary outcome
  • Verbal Fluency26 studies, 13 as a primary outcome
  • Stroop Color-Word Test11 studies, 6 as a primary outcome
  • Category Fluency6 studies, 2 as a primary outcome
  • Paced Visual Serial Addition Test5 studies, 2 as a primary outcome
  • Short Story Recall5 studies, 2 as a primary outcome
  • Continuous Performance Test4 studies, 3 as a primary outcome

Largest condition groups

  • Cancer58 studies, 27 as a primary outcome
  • Multiple sclerosis6 studies, 1 as a primary outcome
  • Mild cognitive impairment4 studies, 1 as a primary outcome
  • Depression and bipolar disorder3 studies, 2 as a primary outcome
  • Dementia and Alzheimer's2 studies, 0 as a primary outcome
  • Sleep and sleep disorders2 studies, 1 as a primary outcome
  • Pain and fatigue2 studies, 2 as a primary outcome
  • Stroke1 study, 0 as a primary outcome
  • Aging, frailty and exercise1 study, 1 as a primary outcome
  • Obesity and diabetes1 study, 0 as a primary outcome
  • Substance use and addiction1 study, 0 as a primary outcome
  • COVID-19 and long COVID1 study, 1 as a primary outcome

Phases

Participants

Lead sponsor: industry 6, NIH 1, other 51. Interventional 41, observational 17.

As a primary outcomeSecondary or other outcomeSymbol Coding

The studies, newest registration first

Each number opens the study's record on ClinicalTrials.gov.

Registered studies that match the filters, newest registration first, with the library tests each one names and the outcome list that names them.
StudyStartPhaseConditionsParticipantsLead sponsorStatusLibrary tests named, with the latest time point
NCT07836478Start2026PhaseObservationalConditionsCancerParticipants60Lead sponsorOtherStatusNot yet recruitingLibrary tests named
  • Verbal LearningSecondary5 years
  • Symbol CodingSecondary5 years
  • Complex Figure Copy and RecallSecondary5 years
  • Corsi Block-Tapping TestSecondary5 years
NCT07710131Start2026PhaseNot applicableConditionsCancerParticipants36Lead sponsorOtherStatusNot yet recruitingLibrary tests named
  • Trail Making TestPrimary
  • Digit Span TestPrimary
  • Symbol CodingPrimary
  • Word Pair LearningPrimary
NCT07652476Start2026PhaseObservationalConditionsCancerParticipants100Lead sponsorOtherStatusNot yet recruitingLibrary tests named
  • Trail Making TestPrimarysame day
  • Stroop Color-Word TestPrimarysame day
  • Verbal LearningPrimarysame day
  • Verbal FluencyPrimarysame day
  • Digit Span TestPrimarysame day
  • Symbol CodingPrimarysame day
  • Picture Naming TestPrimarysame day
  • Complex Figure Copy and RecallPrimarysame day
  • Corsi Block-Tapping TestPrimarysame day
NCT07633626Start2026PhaseObservationalConditionsDepression and bipolar disorder, CancerParticipants24Lead sponsorOtherStatusRecruitingLibrary tests named
  • Trail Making TestPrimary12 weeks
  • Verbal LearningPrimary12 weeks
  • Verbal FluencyPrimary12 weeks
  • Digit Span TestPrimary12 weeks
  • Symbol CodingPrimary12 weeks
  • Symbol Scan TaskPrimary12 weeks
NCT07479927Start2025PhaseNot applicableConditionsCancerParticipants40Lead sponsorOtherStatusRecruitingLibrary tests named
  • Stroop Color-Word TestPrimarysame day
  • Verbal FluencyPrimarysame day
  • Symbol CodingPrimarysame day
  • Continuous Performance TestPrimarysame day
  • Category FluencyPrimarysame day
NCT07463781Start2026PhaseObservationalConditionsCancerParticipants100Lead sponsorOtherStatusNot yet recruitingLibrary tests named
  • Trail Making TestPrimary2 years
  • Verbal LearningPrimary2 years
  • Verbal FluencyPrimary2 years
  • Symbol CodingPrimary2 years
  • Complex Figure Copy and RecallPrimary2 years
NCT07341217Start2026PhaseNot applicableConditionsCancer, Aging, frailty and exerciseParticipants86Lead sponsorOtherStatusRecruitingLibrary tests named
  • Symbol CodingPrimary3 days
  • Rapid Visual Information ProcessingPrimary3 days
  • Size Order Memory TestPrimary3 days
NCT06937554Start2025PhaseObservationalConditionsCancerParticipants30Lead sponsorOtherStatusRecruitingLibrary tests named
  • Symbol CodingPrimary3 weeks
NCT06727370Start2024PhaseObservationalConditionsCancer, Lung diseaseParticipants200Lead sponsorOtherStatusRecruitingLibrary tests named
  • Trail Making TestPrimary12 months
  • Stroop Color-Word TestPrimary12 months
  • Verbal LearningPrimary12 months
  • Verbal FluencyPrimary12 months
  • Digit Span TestPrimary12 months
  • Symbol CodingPrimary12 months
  • Corsi Block-Tapping TestPrimary12 months
NCT06610617Start2024PhaseNot applicableConditionsCancerParticipants48Lead sponsorOtherStatusCompletedLibrary tests named
  • Symbol CodingSecondary9 weeks
NCT06606535Start2024PhaseObservationalConditionsCancerParticipants60Lead sponsorOtherStatusStatus unknownLibrary tests named
  • Trail Making TestPrimary
  • Digit Span TestPrimary
  • Symbol CodingPrimary
  • Short Story RecallPrimary
NCT06553235Start2024PhaseNot applicableConditionsCancer, Sleep and sleep disordersParticipants84Lead sponsorOtherStatusRecruitingLibrary tests named
  • Trail Making TestSecondary8 months
  • Stroop Color-Word TestSecondary8 months
  • Verbal LearningSecondary8 months
  • Verbal FluencySecondary8 months
  • Digit Span TestSecondary8 months
  • Symbol CodingSecondary8 months
  • Continuous Performance TestPrimary8 months
  • Psychomotor Vigilance TaskSecondary8 months
  • Paced Visual Serial Addition TestSecondary8 months
NCT06468176Start2024PhaseNot applicableConditionsCancerParticipants187Lead sponsorOtherStatusRecruitingLibrary tests named
  • Trail Making TestSecondary12 months
  • Stroop Color-Word TestSecondary12 months
  • Verbal LearningSecondary12 months
  • Verbal FluencySecondary12 months
  • Digit Span TestSecondary12 months
  • Symbol CodingSecondary12 months
  • Task Switching TestSecondary12 months
  • Delayed Recall ModuleSecondary12 months
  • Recognition Memory TestSecondary12 months
NCT06330298Start2021PhaseNot applicableConditionsStroke, Multiple sclerosis, CancerParticipants84Lead sponsorOtherStatusStatus unknownLibrary tests named
  • Trail Making TestOther outcomesame day
  • Verbal LearningOther outcomesame day
  • Verbal FluencyOther outcomesame day
  • Digit Span TestOther outcomesame day
  • Symbol CodingOther outcomesame day
  • Category FluencyOther outcomesame day
  • Social Slips Stories TaskSecondary10 months
NCT06219902Start2024PhasePhase 1ConditionsCancerParticipants64Lead sponsorIndustryStatusCompleted

Paper

Library tests named
  • Symbol CodingSecondarysame day
NCT06136923Start2023PhaseNot applicableConditionsMultiple sclerosis, CancerParticipants194Lead sponsorIndustryStatusCompletedLibrary tests named
  • Symbol CodingSecondary4 weeks
NCT06112639Start2024PhaseNot applicableConditionsDementia and Alzheimer's, Mild cognitive impairment, Multiple sclerosis, CancerParticipants192Lead sponsorOtherStatusRecruitingLibrary tests named
  • Trail Making TestSecondary6 months
  • Stroop Color-Word TestSecondary6 months
  • Verbal FluencySecondary6 months
  • Symbol CodingSecondary6 months
  • Category FluencySecondary6 months
  • Selective Reminding TaskSecondary6 months
  • Delayed Recall ModuleSecondary6 months
NCT06103318Start2024PhaseNot applicableConditionsCancerParticipants176Lead sponsorOtherStatusStatus unknownLibrary tests named
  • Trail Making TestPrimary12 months
  • Verbal LearningPrimary12 months
  • Verbal FluencyPrimary12 months
  • Digit Span TestPrimary12 months
  • Symbol CodingPrimary12 months
NCT06055231Start2026PhasePhase 1ConditionsCancer, Substance use and addictionParticipants40Lead sponsorOtherStatusNot yet recruitingLibrary tests named
  • Symbol CodingSecondary2 weeks
  • Paced Visual Serial Addition TestSecondary2 weeks
NCT05907265Start2023PhaseNot applicableConditionsCancerParticipants60Lead sponsorOtherStatusRecruitingLibrary tests named
  • Trail Making TestPrimary12 weeks
  • Stroop Color-Word TestPrimary12 weeks
  • Verbal LearningPrimary12 weeks
  • Verbal FluencyPrimary12 weeks
  • Digit Span TestPrimary12 weeks
  • Symbol CodingPrimary12 weeks
  • Continuous Performance TestPrimary12 weeks
  • Vocabulary TestPrimary12 weeks
NCT05896189Start2024PhaseNot applicableConditionsCancerParticipants386Lead sponsorOtherStatusActive, not recruitingLibrary tests named
  • Symbol CodingSecondary8 months
NCT05716542Start2023PhaseNot applicableConditionsCancerParticipants41Lead sponsorOtherStatusCompletedLibrary tests named
  • Trail Making TestSecondary12 weeks
  • Symbol CodingSecondary12 weeks
  • N-Back TaskSecondary12 weeks
  • Task Switching TestSecondary12 weeks
NCT05708716Start2022PhaseNot applicableConditionsCancerParticipants80Lead sponsorOtherStatusRecruitingLibrary tests named
  • Verbal FluencyPrimary12 weeks
  • Digit Span TestPrimary12 weeks
  • Symbol CodingPrimary12 weeks
  • Short Story RecallPrimary12 weeks
  • Letter-Number Sequencing TaskPrimary12 weeks
NCT05704855Start2023PhaseNot applicableConditionsCancerParticipants21Lead sponsorOtherStatusCompleted

Paper

Library tests named
  • Verbal LearningSecondary8 weeks
  • Symbol CodingSecondary8 weeks
  • Vocabulary TestSecondary8 weeks
  • Picture Order Memory TestSecondary8 weeks
NCT05671094Start2023PhaseNot applicableConditionsCancerParticipants21Lead sponsorOtherStatusCompletedLibrary tests named
  • Verbal LearningSecondary13 weeks
  • Digit Span TestSecondary13 weeks
  • Symbol CodingSecondary13 weeks

Page 1 of 3

Questions, answered from the data

How many cancer trials use Symbol Coding?

58 registered cancer studies on ClinicalTrials.gov name it in an outcome measure, 27 of them in a primary outcome: 8% of the condition's 760 studies with a cognitive outcome, against 9% of all of them. It is the 6th most named test in cancer trials.

Which tests do cancer trials use with Symbol Coding?

Verbal Learning (32 studies), the Digit Span Test (27 studies) and the Trail Making Test (27 studies).

When do cancer trials measure Symbol Coding?

Half of the primary outcomes that name Symbol Coding are measured within 6 months of the start, and the middle half from 12 weeks to 12 months. 25 primary outcomes give a duration.

How many completed cancer trials that use Symbol Coding have reported results?

10 of the 20 completed studies that name it, 50%, have reported results: 6 posted them on ClinicalTrials.gov, 7 have a results paper linked to the registry record, and 3 did both. The other 10 show neither. Of all completed studies with a cognitive outcome, 46% have reported results.

More on Symbol Coding and cancer

  • Every cognitive test in cancer trials: 760 studies
  • Symbol Coding in all clinical trials: 1,457 studies

Symbol Coding in other conditions

  • Multiple sclerosis375
  • Depression and bipolar disorder143
  • Dementia and Alzheimer's117
  • Aging, frailty and exercise116
  • Sleep and sleep disorders89
  • Mild cognitive impairment84
  • Pain and fatigue82
  • Stroke61
  • Substance use and addiction60
  • Obesity and diabetes59
  • Healthy volunteers56

Other tests in cancer trials

  • Verbal Learning235
  • Verbal Fluency200
  • Trail Making Test187
  • Digit Span Test107
  • Stroop Color-Word Test65

How the studies are counted

For each test family, the census runs ClinicalTrials.gov's own outcome search for the family's names and reads every study first posted by the day the family was counted. These studies were read on 10 November 2026. A study counts once on a page, however many tests it names. Counts for a test cover every version of the task under any of its names, so a page can count studies that used a commercial version.

The census adds two things to each record and changes nothing in it: which outcome list names the test (primary, then secondary, then other), and the condition groups, matched on the study's condition names and MeSH terms. A study can fall in several groups; one whose only condition is cognitive impairment or decline falls in “Cognitive impairment and decline”. Studies that name only instruments outside the library count in every total and share but are not listed.

A second read on 10 November 2026 added each study's overall status, whether results are posted, its intervention types, the countries of its sites and the time frame of the outcome that names each test. A time frame counts by the latest time point it names: “Baseline, 12 and 24 weeks” is 24 weeks, a single visit is within a day, and one that names no duration, such as “end of treatment”, is left out of the timings.

A third read on 10 November 2026 added the papers the registry links to each study: those its sponsor lists as reporting results, and those PubMed links to it through the study's NCT number. A study has a results paper when one of them came out in or after the month of its primary completion and PubMed does not class it as a protocol, review or comment. A paper that never gives the NCT number is not linked, so some studies counted as reporting neither did publish.

Source: ClinicalTrials.gov, a database of the U.S. National Library of Medicine, which does not endorse these pages. Every study line is in the data release 2.1.0, and the explorer's own file is clinical-trials-studies.json.

The census counts Symbol Key Game and Symbol Coding as one test family, so this page counts their studies together.

Run Symbol Coding in your trial

Choose tests with a record in registered trials, and run them in a browser at every site, on the same version each visit.

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