Clinical trials data

Symbol Coding in aging, frailty and exercise trials: 116 registered studies

Every registered aging, frailty and exercise study on ClinicalTrials.gov that names Symbol Coding in an outcome measure: how often it is a primary outcome, the tests named with it, how large the studies are and when they measure it.

Registered aging, frailty and exercise studies name it in an outcome measure: 116
Name it in a primary outcome, 29%: 34 of 116
Of the condition's 1,398 studies name it, against 9% of all registered studies: 8%; Other conditions
Median participants per study: 80; By phase

Try the Symbol Key Game Try Symbol Coding

Tests named in the same studies

The library tests that aging, frailty and exercise studies naming Symbol Coding name most often beside it.

1
Trail Making Test52 studies, 17 as a primary outcome
2
Verbal Learning33 studies, 11 as a primary outcome
3
Digit Span Test30 studies, 12 as a primary outcome
4
Stroop Color-Word Test30 studies, 10 as a primary outcome
5
Verbal Fluency21 studies, 9 as a primary outcome
6
N-Back Task12 studies, 5 as a primary outcome
7
Task Switching Test9 studies, 5 as a primary outcome
8
Short Story Recall8 studies, 4 as a primary outcome
9
Matrix Reasoning8 studies, 2 as a primary outcome
10
Selective Reminding Task7 studies, 1 as a primary outcome

A test as a primary outcomeOnly in secondary or other outcomes

Studies by start year

Each study counted once. 2026 is partly planned starts.

A test as a primary outcomeOnly in secondary or other outcomes

Show as a table

Registered studies by start year
Start year	Studies	A test as a primary outcome
2000	0	0
2001	0	0
2002	0	0
2003	0	0
2004	0	0
2005	0	0
2006	0	0
2007	0	0
2008	1	1
2009	0	0
2010	1	0
2011	0	0
2012	0	0
2013	3	1
2014	1	0
2015	3	0
2016	5	2
2017	5	2
2018	9	2
2019	7	1
2020	5	0
2021	9	3
2022	9	2
2023	11	3
2024	12	1
2025	21	11
2026	13	5

Phases and study sizes

By phase

Early phase 11 studies, 0 as a primary outcome
Phase 11 studies, 0 as a primary outcome
Phase 1/22 studies, 1 as a primary outcome
Phase 21 studies, 0 as a primary outcome
Phase 32 studies, 1 as a primary outcome
Phase 42 studies, 1 as a primary outcome
Not applicable90 studies, 29 as a primary outcome
Observational17 studies, 2 as a primary outcome

Participants per study

Not applicable82 median, 45 to 135
Observational92 median, 60 to 212

Participants per study. The bar spans the middle half of the studies in each phase, the mark is the median, and the axis is logarithmic. Phases with fewer than 10 studies that give a size are left out.

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Participants per aging, frailty and exercise study that names Symbol Coding, by phase
Phase	Studies with a size	Median	Middle half
Not applicable	89	82	45 to 135
Observational	17	92	60 to 212

When aging, frailty and exercise trials measure it

Half of the primary outcomes that name Symbol Coding are measured within 12 weeks of the start, and the middle half from 5 weeks to 5 months. 34 primary outcomes give a duration.

Latest time point of each outcome

Within a day17 outcomes, 4 as a primary outcome
Up to 4 weeks10 outcomes, 5 as a primary outcome
1 to 3 months35 outcomes, 14 as a primary outcome
3 to 6 months27 outcomes, 5 as a primary outcome
6 to 12 months11 outcomes, 2 as a primary outcome
1 to 2 years7 outcomes, 1 as a primary outcome
Over 2 years7 outcomes, 3 as a primary outcome
No duration given2 outcomes, 0 as a primary outcome

A test as a primary outcomeOnly in secondary or other outcomes

114 of the 116 outcome measures give a duration. A single visit counts as within a day.

Status, results, interventions and countries

Status

Recruiting24 studies, 9 as a primary outcome
Not yet recruiting10 studies, 3 as a primary outcome
Active, not recruiting10 studies, 5 as a primary outcome
Completed58 studies, 15 as a primary outcome
Stopped early2 studies, 0 as a primary outcome
Status unknown12 studies, 2 as a primary outcome

What they test

Behavioral46 studies, 16 as a primary outcome
Drug5 studies, 1 as a primary outcome
Device10 studies, 2 as a primary outcome
Dietary supplement14 studies, 4 as a primary outcome
Procedure3 studies, 2 as a primary outcome
Diagnostic test5 studies, 1 as a primary outcome
Biological1 studies, 0 as a primary outcome
Combination product2 studies, 1 as a primary outcome
Genetic1 studies, 0 as a primary outcome
Other40 studies, 9 as a primary outcome
None given6 studies, 1 as a primary outcome

Intervention types as registered. A study can list several; observational studies often list none.

32 countries in all. A study with sites in several counts in each; 3 list no site.

Reported results

Completed studies with results posted on ClinicalTrials.gov, a results paper the registry links to the study, or both.

Completed aging, frailty and exercise studies that name Symbol Coding: 23 of 58, 40%

Every completed study with a cognitive outcome: 3,626 of 7,953, 46%

Completed aging, frailty and exercise studies that name Symbol Coding and every completed study, by how they reported results
Results	Completed aging, frailty and exercise studies that name Symbol Coding	Every completed study
Results on ClinicalTrials.gov and a paper	3, 5%	776, 10%
Results on ClinicalTrials.gov only	4, 7%	1,139, 14%
A results paper only	16, 28%	1,711, 22%
Neither	35, 60%	4,327, 54%

The 116 studies

Filter by phase, sponsor, status, country, intervention, outcome list, size and start year. Each study links to its record on ClinicalTrials.gov.

116 studies match. 34 name Symbol Coding in a primary outcome. Median size 80 participants. Median time to the primary outcome: 12 weeks.

Loading 116 studies; the filters turn on when they arrive.

By start year

2026 is partly planned starts. Not shown: 1 planned to start after 2026.

Show as a table

Matching studies by start year
Start year	Studies	As a primary outcome
2000	0	0
2001	0	0
2002	0	0
2003	0	0
2004	0	0
2005	0	0
2006	0	0
2007	0	0
2008	1	1
2009	0	0
2010	1	0
2011	0	0
2012	0	0
2013	3	1
2014	1	0
2015	3	0
2016	5	2
2017	5	2
2018	9	2
2019	7	1
2020	5	0
2021	9	3
2022	9	2
2023	11	3
2024	12	1
2025	21	11
2026	13	5

Library tests named most

Largest condition groups

Aging, frailty and exercise116 studies, 34 as a primary outcome
Healthy volunteers12 studies, 5 as a primary outcome
Multiple sclerosis11 studies, 2 as a primary outcome
Dementia and Alzheimer's9 studies, 2 as a primary outcome
Mild cognitive impairment8 studies, 4 as a primary outcome
Obesity and diabetes8 studies, 2 as a primary outcome
Cardiovascular disease7 studies, 2 as a primary outcome
Depression and bipolar disorder5 studies, 1 as a primary outcome
Parkinson's disease3 studies, 1 as a primary outcome
Sleep and sleep disorders3 studies, 1 as a primary outcome
Anxiety, PTSD and OCD2 studies, 0 as a primary outcome
Hearing loss2 studies, 1 as a primary outcome

Phases

Participants

Lead sponsor: industry 8, other 108. Interventional 99, observational 17.

As a primary outcomeSecondary or other outcomeSymbol Coding

The studies, newest registration first

Each number opens the study's record on ClinicalTrials.gov.

Registered studies that match the filters, newest registration first, with the library tests each one names and the outcome list that names them.
Study	Start	Phase	Conditions	Participants	Lead sponsor	Status	Library tests named, with the latest time point
NCT07902206	Start2026	PhaseNot applicable	ConditionsAging, frailty and exercise, Huntington's disease	Participants88	Lead sponsorOther	StatusNot yet recruiting	Library tests named Trail Making TestSecondary6 months Stroop Color-Word TestSecondary6 months Verbal FluencySecondary6 months Symbol CodingSecondary6 months
NCT07890753	Start2026	PhaseObservational	ConditionsAging, frailty and exercise	Participants60	Lead sponsorOther	StatusNot yet recruiting	Library tests named Symbol CodingSecondary2 years
NCT07852572	Start2027	PhaseNot applicable	ConditionsAging, frailty and exercise	Participants204	Lead sponsorOther	StatusNot yet recruiting	Library tests named Symbol CodingSecondary6 months
NCT07827651	Start2025	PhaseNot applicable	ConditionsHealthy volunteers, Aging, frailty and exercise, Sleep and sleep disorders	Participants64	Lead sponsorIndustry	StatusActive, not recruiting	Library tests named Symbol CodingSecondary12 weeks
NCT07769411	Start2026	PhaseNot applicable	ConditionsAging, frailty and exercise	Participants108	Lead sponsorOther	StatusCompleted	Library tests named Symbol CodingPrimary12 weeks
NCT07738120	Start2025	PhaseNot applicable	ConditionsMultiple sclerosis, Aging, frailty and exercise	Participants30	Lead sponsorOther	StatusRecruiting	Library tests named Symbol CodingPrimarysame day
NCT07701317	Start2025	PhaseNot applicable	ConditionsAging, frailty and exercise	Participants108	Lead sponsorOther	StatusCompleted	Library tests named Stroop Color-Word TestPrimary6 weeks Verbal FluencyPrimary6 weeks Digit Span TestPrimary6 weeks Symbol CodingPrimary6 weeks
NCT07668908	Start2026	PhaseNot applicable	ConditionsAging, frailty and exercise	Participants20	Lead sponsorOther	StatusRecruiting	Library tests named Symbol CodingPrimary12 weeks Clock Drawing TaskPrimary12 weeks
NCT07666685	Start2026	PhaseNot applicable	ConditionsAging, frailty and exercise, Cardiovascular disease	Participants120	Lead sponsorOther	StatusRecruiting	Library tests named Trail Making TestPrimary12 weeks Stroop Color-Word TestPrimary12 weeks Symbol CodingPrimary12 weeks Task Switching TestPrimary12 weeks
NCT07633392	Start2026	PhaseNot applicable	ConditionsAging, frailty and exercise, Substance use and addiction, Sleep and sleep disorders, Cardiovascular disease	Participants240	Lead sponsorOther	StatusRecruiting	Library tests named Trail Making TestSecondary4 months Symbol CodingSecondary4 months
NCT07623122	Start2024	PhaseNot applicable	ConditionsHealthy volunteers, Aging, frailty and exercise	Participants120	Lead sponsorOther	StatusCompleted	Library tests named Trail Making TestSecondary4 weeks Symbol CodingSecondary4 weeks Clock Drawing TaskSecondary4 weeks
NCT07544420	Start2026	PhasePhase 1	ConditionsAging, frailty and exercise	Participants21	Lead sponsorIndustry	StatusNot yet recruiting	Library tests named Symbol CodingOther outcome9 weeks Eriksen Flanker TaskOther outcome9 weeks Size Order Memory TestOther outcome9 weeks Face-name Memory TaskOther outcome9 weeks
NCT07543900	Start2024	PhaseNot applicable	ConditionsMultiple sclerosis, Aging, frailty and exercise	Participants5	Lead sponsorOther	StatusCompleted	Library tests named Symbol CodingSecondarysame day
NCT07504120	Start2025	PhaseNot applicable	ConditionsMultiple sclerosis, Depression and bipolar disorder, Aging, frailty and exercise, Pain and fatigue	Participants50	Lead sponsorOther	StatusRecruiting	Library tests named Verbal LearningSecondary16 weeks Symbol CodingSecondary16 weeks
NCT07497334	Start2025	PhaseNot applicable	ConditionsMild cognitive impairment, Aging, frailty and exercise	Participants45	Lead sponsorOther	StatusRecruiting	Library tests named Trail Making TestSecondary6 months Stroop Color-Word TestSecondary6 months Digit Span TestSecondary6 months Symbol CodingSecondary6 months Task Switching TestSecondary6 months
NCT07485062	Start2026	PhasePhase 4	ConditionsAging, frailty and exercise, Obesity and diabetes	Participants164	Lead sponsorOther	StatusNot yet recruiting	Library tests named Trail Making TestPrimary7 months Stroop Color-Word TestSecondary7 months Verbal LearningSecondary7 months Digit Span TestSecondary7 months Symbol CodingSecondary7 months Eriksen Flanker TaskSecondary7 months
NCT07392944	Start2026	PhaseNot applicable	ConditionsDementia and Alzheimer's, Aging, frailty and exercise	Participants60	Lead sponsorOther	StatusRecruiting	Library tests named Trail Making TestSecondary4 months Symbol CodingSecondary4 months
NCT07378566	Start2026	PhaseNot applicable	ConditionsMultiple sclerosis, Aging, frailty and exercise	Participants80	Lead sponsorOther	StatusNot yet recruiting	Library tests named Symbol CodingOther outcomesame day
NCT07341217	Start2026	PhaseNot applicable	ConditionsCancer, Aging, frailty and exercise	Participants86	Lead sponsorOther	StatusRecruiting	Library tests named Symbol CodingPrimary3 days Rapid Visual Information ProcessingPrimary3 days Size Order Memory TestPrimary3 days
NCT07292428	Start2026	PhaseNot applicable	ConditionsAging, frailty and exercise	Participants80	Lead sponsorOther	StatusRecruiting	Library tests named Trail Making TestSecondary8 weeks Stroop Color-Word TestSecondary8 weeks Symbol CodingSecondary8 weeks
NCT07248657	Start2025	PhaseNot applicable	ConditionsMultiple sclerosis, Aging, frailty and exercise	Participants26	Lead sponsorOther	StatusNot yet recruiting	Library tests named Symbol CodingPrimary4 months
NCT07209683	Start2025	PhaseNot applicable	ConditionsAging, frailty and exercise	Participants30	Lead sponsorOther	StatusRecruiting	Library tests named Symbol CodingPrimary4 weeks N-Back TaskSecondary4 weeks Dimensional Change Card SortPrimary4 weeks Size Order Memory TestPrimary4 weeks Pattern and Letter ComparisonPrimary4 weeks
NCT07208279	Start2025	PhaseNot applicable	ConditionsHealthy volunteers, Aging, frailty and exercise	Participants16	Lead sponsorOther	StatusRecruiting	Library tests named Verbal LearningPrimary6 weeks Digit Span TestPrimary6 weeks Symbol CodingPrimary6 weeks
NCT07170943	Start2021	PhaseNot applicable	ConditionsAging, frailty and exercise	ParticipantsNot given	Lead sponsorOther	StatusStopped early	Library tests named Trail Making TestSecondary12 weeks Stroop Color-Word TestSecondary12 weeks Verbal LearningSecondary12 weeks Verbal FluencyPrimary12 weeks Digit Span TestSecondary12 weeks Symbol CodingSecondary12 weeks
NCT07165977	Start2024	PhaseNot applicable	ConditionsAging, frailty and exercise	Participants110	Lead sponsorOther	StatusActive, not recruiting	Library tests named Verbal LearningPrimary13 weeks Digit Span TestSecondary13 weeks Symbol CodingSecondary13 weeks Matrix ReasoningOther outcome Cancellation TestSecondary13 weeks Recognition Memory TestPrimary13 weeks Block Copy TestSecondary13 weeks

Questions, answered from the data

How many aging, frailty and exercise trials use Symbol Coding?

116 registered aging, frailty and exercise studies on ClinicalTrials.gov name it in an outcome measure, 34 of them in a primary outcome: 8% of the condition's 1,398 studies with a cognitive outcome, against 9% of all of them. It is the 6th most named test in aging, frailty and exercise trials.

Which tests do aging, frailty and exercise trials use with Symbol Coding?

The Trail Making Test (52 studies), Verbal Learning (33 studies) and the Digit Span Test (30 studies).

When do aging, frailty and exercise trials measure Symbol Coding?

Half of the primary outcomes that name Symbol Coding are measured within 12 weeks of the start, and the middle half from 5 weeks to 5 months. 34 primary outcomes give a duration.

How many completed aging, frailty and exercise trials that use Symbol Coding have reported results?

23 of the 58 completed studies that name it, 40%, have reported results: 7 posted them on ClinicalTrials.gov, 19 have a results paper linked to the registry record, and 3 did both. The other 35 show neither. Of all completed studies with a cognitive outcome, 46% have reported results.

How the studies are counted

For each test family, the census runs ClinicalTrials.gov's own outcome search for the family's names and reads every study first posted by the day the family was counted. These studies were read on 10 November 2026. A study counts once on a page, however many tests it names. Counts for a test cover every version of the task under any of its names, so a page can count studies that used a commercial version.

The census adds two things to each record and changes nothing in it: which outcome list names the test (primary, then secondary, then other), and the condition groups, matched on the study's condition names and MeSH terms. A study can fall in several groups; one whose only condition is cognitive impairment or decline falls in “Cognitive impairment and decline”. Studies that name only instruments outside the library count in every total and share but are not listed.

A second read on 10 November 2026 added each study's overall status, whether results are posted, its intervention types, the countries of its sites and the time frame of the outcome that names each test. A time frame counts by the latest time point it names: “Baseline, 12 and 24 weeks” is 24 weeks, a single visit is within a day, and one that names no duration, such as “end of treatment”, is left out of the timings.

A third read on 10 November 2026 added the papers the registry links to each study: those its sponsor lists as reporting results, and those PubMed links to it through the study's NCT number. A study has a results paper when one of them came out in or after the month of its primary completion and PubMed does not class it as a protocol, review or comment. A paper that never gives the NCT number is not linked, so some studies counted as reporting neither did publish.

Source: ClinicalTrials.gov, a database of the U.S. National Library of Medicine, which does not endorse these pages. Every study line is in the data release 2.1.0, and the explorer's own file is clinical-trials-studies.json.

The census counts Symbol Key Game and Symbol Coding as one test family, so this page counts their studies together.

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Choose tests with a record in registered trials, and run them in a browser at every site, on the same version each visit.

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Clinical trials data

Symbol Coding in aging, frailty and exercise trials: 116 registered studies

Registered aging, frailty and exercise studies name it in an outcome measure: 116
Name it in a primary outcome, 29%: 34 of 116
Of the condition's 1,398 studies name it, against 9% of all registered studies: 8%; Other conditions
Median participants per study: 80; By phase

Try the Symbol Key Game Try Symbol Coding

Tests named in the same studies

The library tests that aging, frailty and exercise studies naming Symbol Coding name most often beside it.

1
Trail Making Test52 studies, 17 as a primary outcome
2
Verbal Learning33 studies, 11 as a primary outcome
3
Digit Span Test30 studies, 12 as a primary outcome
4
Stroop Color-Word Test30 studies, 10 as a primary outcome
5
Verbal Fluency21 studies, 9 as a primary outcome
6
N-Back Task12 studies, 5 as a primary outcome
7
Task Switching Test9 studies, 5 as a primary outcome
8
Short Story Recall8 studies, 4 as a primary outcome
9
Matrix Reasoning8 studies, 2 as a primary outcome
10
Selective Reminding Task7 studies, 1 as a primary outcome

A test as a primary outcomeOnly in secondary or other outcomes

Studies by start year

Each study counted once. 2026 is partly planned starts.

A test as a primary outcomeOnly in secondary or other outcomes

Show as a table

Registered studies by start year
Start year	Studies	A test as a primary outcome
2000	0	0
2001	0	0
2002	0	0
2003	0	0
2004	0	0
2005	0	0
2006	0	0
2007	0	0
2008	1	1
2009	0	0
2010	1	0
2011	0	0
2012	0	0
2013	3	1
2014	1	0
2015	3	0
2016	5	2
2017	5	2
2018	9	2
2019	7	1
2020	5	0
2021	9	3
2022	9	2
2023	11	3
2024	12	1
2025	21	11
2026	13	5

Phases and study sizes

By phase

Early phase 11 studies, 0 as a primary outcome
Phase 11 studies, 0 as a primary outcome
Phase 1/22 studies, 1 as a primary outcome
Phase 21 studies, 0 as a primary outcome
Phase 32 studies, 1 as a primary outcome
Phase 42 studies, 1 as a primary outcome
Not applicable90 studies, 29 as a primary outcome
Observational17 studies, 2 as a primary outcome

Participants per study

Not applicable82 median, 45 to 135
Observational92 median, 60 to 212

Show as a table

Participants per aging, frailty and exercise study that names Symbol Coding, by phase
Phase	Studies with a size	Median	Middle half
Not applicable	89	82	45 to 135
Observational	17	92	60 to 212

When aging, frailty and exercise trials measure it

Half of the primary outcomes that name Symbol Coding are measured within 12 weeks of the start, and the middle half from 5 weeks to 5 months. 34 primary outcomes give a duration.

Latest time point of each outcome

Within a day17 outcomes, 4 as a primary outcome
Up to 4 weeks10 outcomes, 5 as a primary outcome
1 to 3 months35 outcomes, 14 as a primary outcome
3 to 6 months27 outcomes, 5 as a primary outcome
6 to 12 months11 outcomes, 2 as a primary outcome
1 to 2 years7 outcomes, 1 as a primary outcome
Over 2 years7 outcomes, 3 as a primary outcome
No duration given2 outcomes, 0 as a primary outcome

A test as a primary outcomeOnly in secondary or other outcomes

114 of the 116 outcome measures give a duration. A single visit counts as within a day.

Status, results, interventions and countries

Status

Recruiting24 studies, 9 as a primary outcome
Not yet recruiting10 studies, 3 as a primary outcome
Active, not recruiting10 studies, 5 as a primary outcome
Completed58 studies, 15 as a primary outcome
Stopped early2 studies, 0 as a primary outcome
Status unknown12 studies, 2 as a primary outcome

What they test

Behavioral46 studies, 16 as a primary outcome
Drug5 studies, 1 as a primary outcome
Device10 studies, 2 as a primary outcome
Dietary supplement14 studies, 4 as a primary outcome
Procedure3 studies, 2 as a primary outcome
Diagnostic test5 studies, 1 as a primary outcome
Biological1 studies, 0 as a primary outcome
Combination product2 studies, 1 as a primary outcome
Genetic1 studies, 0 as a primary outcome
Other40 studies, 9 as a primary outcome
None given6 studies, 1 as a primary outcome

Intervention types as registered. A study can list several; observational studies often list none.

32 countries in all. A study with sites in several counts in each; 3 list no site.

Reported results

Completed studies with results posted on ClinicalTrials.gov, a results paper the registry links to the study, or both.

Completed aging, frailty and exercise studies that name Symbol Coding: 23 of 58, 40%

Every completed study with a cognitive outcome: 3,626 of 7,953, 46%

Completed aging, frailty and exercise studies that name Symbol Coding and every completed study, by how they reported results
Results	Completed aging, frailty and exercise studies that name Symbol Coding	Every completed study
Results on ClinicalTrials.gov and a paper	3, 5%	776, 10%
Results on ClinicalTrials.gov only	4, 7%	1,139, 14%
A results paper only	16, 28%	1,711, 22%
Neither	35, 60%	4,327, 54%

The 116 studies

Filter by phase, sponsor, status, country, intervention, outcome list, size and start year. Each study links to its record on ClinicalTrials.gov.

116 studies match. 34 name Symbol Coding in a primary outcome. Median size 80 participants. Median time to the primary outcome: 12 weeks.

Loading 116 studies; the filters turn on when they arrive.

By start year

2026 is partly planned starts. Not shown: 1 planned to start after 2026.

Show as a table

Matching studies by start year
Start year	Studies	As a primary outcome
2000	0	0
2001	0	0
2002	0	0
2003	0	0
2004	0	0
2005	0	0
2006	0	0
2007	0	0
2008	1	1
2009	0	0
2010	1	0
2011	0	0
2012	0	0
2013	3	1
2014	1	0
2015	3	0
2016	5	2
2017	5	2
2018	9	2
2019	7	1
2020	5	0
2021	9	3
2022	9	2
2023	11	3
2024	12	1
2025	21	11
2026	13	5

Library tests named most

Largest condition groups

Aging, frailty and exercise116 studies, 34 as a primary outcome
Healthy volunteers12 studies, 5 as a primary outcome
Multiple sclerosis11 studies, 2 as a primary outcome
Dementia and Alzheimer's9 studies, 2 as a primary outcome
Mild cognitive impairment8 studies, 4 as a primary outcome
Obesity and diabetes8 studies, 2 as a primary outcome
Cardiovascular disease7 studies, 2 as a primary outcome
Depression and bipolar disorder5 studies, 1 as a primary outcome
Parkinson's disease3 studies, 1 as a primary outcome
Sleep and sleep disorders3 studies, 1 as a primary outcome
Anxiety, PTSD and OCD2 studies, 0 as a primary outcome
Hearing loss2 studies, 1 as a primary outcome

Phases

Participants

Lead sponsor: industry 8, other 108. Interventional 99, observational 17.

As a primary outcomeSecondary or other outcomeSymbol Coding

The studies, newest registration first

Each number opens the study's record on ClinicalTrials.gov.

Registered studies that match the filters, newest registration first, with the library tests each one names and the outcome list that names them.
Study	Start	Phase	Conditions	Participants	Lead sponsor	Status	Library tests named, with the latest time point
NCT07902206	Start2026	PhaseNot applicable	ConditionsAging, frailty and exercise, Huntington's disease	Participants88	Lead sponsorOther	StatusNot yet recruiting	Library tests named Trail Making TestSecondary6 months Stroop Color-Word TestSecondary6 months Verbal FluencySecondary6 months Symbol CodingSecondary6 months
NCT07890753	Start2026	PhaseObservational	ConditionsAging, frailty and exercise	Participants60	Lead sponsorOther	StatusNot yet recruiting	Library tests named Symbol CodingSecondary2 years
NCT07852572	Start2027	PhaseNot applicable	ConditionsAging, frailty and exercise	Participants204	Lead sponsorOther	StatusNot yet recruiting	Library tests named Symbol CodingSecondary6 months
NCT07827651	Start2025	PhaseNot applicable	ConditionsHealthy volunteers, Aging, frailty and exercise, Sleep and sleep disorders	Participants64	Lead sponsorIndustry	StatusActive, not recruiting	Library tests named Symbol CodingSecondary12 weeks
NCT07769411	Start2026	PhaseNot applicable	ConditionsAging, frailty and exercise	Participants108	Lead sponsorOther	StatusCompleted	Library tests named Symbol CodingPrimary12 weeks
NCT07738120	Start2025	PhaseNot applicable	ConditionsMultiple sclerosis, Aging, frailty and exercise	Participants30	Lead sponsorOther	StatusRecruiting	Library tests named Symbol CodingPrimarysame day
NCT07701317	Start2025	PhaseNot applicable	ConditionsAging, frailty and exercise	Participants108	Lead sponsorOther	StatusCompleted	Library tests named Stroop Color-Word TestPrimary6 weeks Verbal FluencyPrimary6 weeks Digit Span TestPrimary6 weeks Symbol CodingPrimary6 weeks
NCT07668908	Start2026	PhaseNot applicable	ConditionsAging, frailty and exercise	Participants20	Lead sponsorOther	StatusRecruiting	Library tests named Symbol CodingPrimary12 weeks Clock Drawing TaskPrimary12 weeks
NCT07666685	Start2026	PhaseNot applicable	ConditionsAging, frailty and exercise, Cardiovascular disease	Participants120	Lead sponsorOther	StatusRecruiting	Library tests named Trail Making TestPrimary12 weeks Stroop Color-Word TestPrimary12 weeks Symbol CodingPrimary12 weeks Task Switching TestPrimary12 weeks
NCT07633392	Start2026	PhaseNot applicable	ConditionsAging, frailty and exercise, Substance use and addiction, Sleep and sleep disorders, Cardiovascular disease	Participants240	Lead sponsorOther	StatusRecruiting	Library tests named Trail Making TestSecondary4 months Symbol CodingSecondary4 months
NCT07623122	Start2024	PhaseNot applicable	ConditionsHealthy volunteers, Aging, frailty and exercise	Participants120	Lead sponsorOther	StatusCompleted	Library tests named Trail Making TestSecondary4 weeks Symbol CodingSecondary4 weeks Clock Drawing TaskSecondary4 weeks
NCT07544420	Start2026	PhasePhase 1	ConditionsAging, frailty and exercise	Participants21	Lead sponsorIndustry	StatusNot yet recruiting	Library tests named Symbol CodingOther outcome9 weeks Eriksen Flanker TaskOther outcome9 weeks Size Order Memory TestOther outcome9 weeks Face-name Memory TaskOther outcome9 weeks
NCT07543900	Start2024	PhaseNot applicable	ConditionsMultiple sclerosis, Aging, frailty and exercise	Participants5	Lead sponsorOther	StatusCompleted	Library tests named Symbol CodingSecondarysame day
NCT07504120	Start2025	PhaseNot applicable	ConditionsMultiple sclerosis, Depression and bipolar disorder, Aging, frailty and exercise, Pain and fatigue	Participants50	Lead sponsorOther	StatusRecruiting	Library tests named Verbal LearningSecondary16 weeks Symbol CodingSecondary16 weeks
NCT07497334	Start2025	PhaseNot applicable	ConditionsMild cognitive impairment, Aging, frailty and exercise	Participants45	Lead sponsorOther	StatusRecruiting	Library tests named Trail Making TestSecondary6 months Stroop Color-Word TestSecondary6 months Digit Span TestSecondary6 months Symbol CodingSecondary6 months Task Switching TestSecondary6 months
NCT07485062	Start2026	PhasePhase 4	ConditionsAging, frailty and exercise, Obesity and diabetes	Participants164	Lead sponsorOther	StatusNot yet recruiting	Library tests named Trail Making TestPrimary7 months Stroop Color-Word TestSecondary7 months Verbal LearningSecondary7 months Digit Span TestSecondary7 months Symbol CodingSecondary7 months Eriksen Flanker TaskSecondary7 months
NCT07392944	Start2026	PhaseNot applicable	ConditionsDementia and Alzheimer's, Aging, frailty and exercise	Participants60	Lead sponsorOther	StatusRecruiting	Library tests named Trail Making TestSecondary4 months Symbol CodingSecondary4 months
NCT07378566	Start2026	PhaseNot applicable	ConditionsMultiple sclerosis, Aging, frailty and exercise	Participants80	Lead sponsorOther	StatusNot yet recruiting	Library tests named Symbol CodingOther outcomesame day
NCT07341217	Start2026	PhaseNot applicable	ConditionsCancer, Aging, frailty and exercise	Participants86	Lead sponsorOther	StatusRecruiting	Library tests named Symbol CodingPrimary3 days Rapid Visual Information ProcessingPrimary3 days Size Order Memory TestPrimary3 days
NCT07292428	Start2026	PhaseNot applicable	ConditionsAging, frailty and exercise	Participants80	Lead sponsorOther	StatusRecruiting	Library tests named Trail Making TestSecondary8 weeks Stroop Color-Word TestSecondary8 weeks Symbol CodingSecondary8 weeks
NCT07248657	Start2025	PhaseNot applicable	ConditionsMultiple sclerosis, Aging, frailty and exercise	Participants26	Lead sponsorOther	StatusNot yet recruiting	Library tests named Symbol CodingPrimary4 months
NCT07209683	Start2025	PhaseNot applicable	ConditionsAging, frailty and exercise	Participants30	Lead sponsorOther	StatusRecruiting	Library tests named Symbol CodingPrimary4 weeks N-Back TaskSecondary4 weeks Dimensional Change Card SortPrimary4 weeks Size Order Memory TestPrimary4 weeks Pattern and Letter ComparisonPrimary4 weeks
NCT07208279	Start2025	PhaseNot applicable	ConditionsHealthy volunteers, Aging, frailty and exercise	Participants16	Lead sponsorOther	StatusRecruiting	Library tests named Verbal LearningPrimary6 weeks Digit Span TestPrimary6 weeks Symbol CodingPrimary6 weeks
NCT07170943	Start2021	PhaseNot applicable	ConditionsAging, frailty and exercise	ParticipantsNot given	Lead sponsorOther	StatusStopped early	Library tests named Trail Making TestSecondary12 weeks Stroop Color-Word TestSecondary12 weeks Verbal LearningSecondary12 weeks Verbal FluencyPrimary12 weeks Digit Span TestSecondary12 weeks Symbol CodingSecondary12 weeks
NCT07165977	Start2024	PhaseNot applicable	ConditionsAging, frailty and exercise	Participants110	Lead sponsorOther	StatusActive, not recruiting	Library tests named Verbal LearningPrimary13 weeks Digit Span TestSecondary13 weeks Symbol CodingSecondary13 weeks Matrix ReasoningOther outcome Cancellation TestSecondary13 weeks Recognition Memory TestPrimary13 weeks Block Copy TestSecondary13 weeks

Questions, answered from the data

How many aging, frailty and exercise trials use Symbol Coding?

Which tests do aging, frailty and exercise trials use with Symbol Coding?

The Trail Making Test (52 studies), Verbal Learning (33 studies) and the Digit Span Test (30 studies).

When do aging, frailty and exercise trials measure Symbol Coding?

Half of the primary outcomes that name Symbol Coding are measured within 12 weeks of the start, and the middle half from 5 weeks to 5 months. 34 primary outcomes give a duration.

How many completed aging, frailty and exercise trials that use Symbol Coding have reported results?

How the studies are counted

The census counts Symbol Key Game and Symbol Coding as one test family, so this page counts their studies together.

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Symbol Coding in aging, frailty and exercise trials: 116 registered studies

Tests named in the same studies

Studies by start year

Phases and study sizes

By phase

Participants per study

When aging, frailty and exercise trials measure it

Latest time point of each outcome

Status, results, interventions and countries

Status

What they test

Where their sites are

Reported results

The 116 studies

Library tests named most

Largest condition groups

Phases

Participants

The studies, newest registration first

Questions, answered from the data

How many aging, frailty and exercise trials use Symbol Coding?

Which tests do aging, frailty and exercise trials use with Symbol Coding?

When do aging, frailty and exercise trials measure Symbol Coding?

How many completed aging, frailty and exercise trials that use Symbol Coding have reported results?

More on Symbol Coding and aging, frailty and exercise

Symbol Coding in other conditions

Other tests in aging, frailty and exercise trials

How the studies are counted

Run Symbol Coding in your trial

Symbol Coding in aging, frailty and exercise trials: 116 registered studies

Tests named in the same studies

Studies by start year

Phases and study sizes

By phase

Participants per study

When aging, frailty and exercise trials measure it

Latest time point of each outcome

Status, results, interventions and countries

Status

What they test

Where their sites are

Reported results

The 116 studies

Library tests named most

Largest condition groups

Phases

Participants

The studies, newest registration first

Questions, answered from the data

How many aging, frailty and exercise trials use Symbol Coding?

Which tests do aging, frailty and exercise trials use with Symbol Coding?

When do aging, frailty and exercise trials measure Symbol Coding?

How many completed aging, frailty and exercise trials that use Symbol Coding have reported results?

More on Symbol Coding and aging, frailty and exercise

Symbol Coding in other conditions

Other tests in aging, frailty and exercise trials

How the studies are counted

Run Symbol Coding in your trial