Clinical trials data
N-Back Task in aging, frailty and exercise trials: 68 registered studies
Every registered aging, frailty and exercise study on ClinicalTrials.gov that names the N-Back Task in an outcome measure: how often it is a primary outcome, the tests named with it, how large the studies are and when they measure it.
- Registered aging, frailty and exercise studies name it in an outcome measure
- 68
- Name it in a primary outcome, 57%
- 39 of 68
Tests named in the same studies
- 1
Stroop Color-Word Test17 studies, 13 as a primary outcome
- 2
Trail Making Test13 studies, 6 as a primary outcome
- 3
Symbol Coding12 studies, 3 as a primary outcome
- 4
Eriksen Flanker Task10 studies, 4 as a primary outcome
- 5
Digit Span Test9 studies, 5 as a primary outcome
- 6
Task Switching Test8 studies, 6 as a primary outcome
- 7
Verbal Learning8 studies, 3 as a primary outcome
- 8
Go/No-Go Task6 studies, 3 as a primary outcome
- 9
Pattern and Letter Comparison6 studies, 2 as a primary outcome
- 10
Size Order Memory Test6 studies, 2 as a primary outcome
A test as a primary outcomeOnly in secondary or other outcomes
Studies by start year
A test as a primary outcomeOnly in secondary or other outcomes
Show as a table
| Start year | Studies | A test as a primary outcome |
|---|---|---|
| 2000 | 0 | 0 |
| 2001 | 0 | 0 |
| 2002 | 1 | 0 |
| 2003 | 0 | 0 |
| 2004 | 0 | 0 |
| 2005 | 0 | 0 |
| 2006 | 0 | 0 |
| 2007 | 0 | 0 |
| 2008 | 1 | 0 |
| 2009 | 0 | 0 |
| 2010 | 0 | 0 |
| 2011 | 0 | 0 |
| 2012 | 1 | 0 |
| 2013 | 0 | 0 |
| 2014 | 2 | 0 |
| 2015 | 5 | 2 |
| 2016 | 1 | 1 |
| 2017 | 1 | 1 |
| 2018 | 6 | 4 |
| 2019 | 5 | 2 |
| 2020 | 2 | 2 |
| 2021 | 7 | 4 |
| 2022 | 11 | 9 |
| 2023 | 9 | 4 |
| 2024 | 5 | 3 |
| 2025 | 4 | 2 |
| 2026 | 6 | 4 |
Phases and study sizes
By phase
- Early phase 11 studies, 1 as a primary outcome
- Phase 13 studies, 1 as a primary outcome
- Phase 1/21 studies, 1 as a primary outcome
- Phase 21 studies, 1 as a primary outcome
- Phase 2/31 studies, 1 as a primary outcome
- Phase 41 studies, 1 as a primary outcome
- Not applicable56 studies, 31 as a primary outcome
- Observational4 studies, 2 as a primary outcome
Participants per study
- Not applicable70 median, 33 to 119
Show as a table
| Phase | Studies with a size | Median | Middle half |
|---|---|---|---|
| Not applicable | 55 | 70 | 33 to 119 |
When aging, frailty and exercise trials measure it
Latest time point of each outcome
- Within a day16 outcomes, 8 as a primary outcome
- Up to 4 weeks8 outcomes, 6 as a primary outcome
- 1 to 3 months17 outcomes, 9 as a primary outcome
- 3 to 6 months10 outcomes, 5 as a primary outcome
- 6 to 12 months10 outcomes, 7 as a primary outcome
- 1 to 2 years1 outcomes, 0 as a primary outcome
- Over 2 years3 outcomes, 2 as a primary outcome
- No duration given3 outcomes, 2 as a primary outcome
A test as a primary outcomeOnly in secondary or other outcomes
65 of the 68 outcome measures give a duration. A single visit counts as within a day.
Status, results, interventions and countries
Status
- Recruiting7 studies, 2 as a primary outcome
- Not yet recruiting4 studies, 4 as a primary outcome
- Active, not recruiting2 studies, 1 as a primary outcome
- Completed44 studies, 26 as a primary outcome
- Stopped early2 studies, 1 as a primary outcome
- Status unknown9 studies, 5 as a primary outcome
What they test
- Behavioral31 studies, 19 as a primary outcome
- Drug8 studies, 5 as a primary outcome
- Device10 studies, 6 as a primary outcome
- Dietary supplement5 studies, 2 as a primary outcome
- Biological1 studies, 0 as a primary outcome
- Radiation1 studies, 1 as a primary outcome
- Other20 studies, 9 as a primary outcome
- None given2 studies, 2 as a primary outcome
Intervention types as registered. A study can list several; observational studies often list none.
Where their sites are
- United States26 studies, 13 as a primary outcome
- Canada6 studies, 2 as a primary outcome
- Netherlands4 studies, 3 as a primary outcome
- Spain4 studies, 2 as a primary outcome
- China3 studies, 2 as a primary outcome
- Czechia3 studies, 2 as a primary outcome
- Germany3 studies, 1 as a primary outcome
- Hong Kong2 studies, 0 as a primary outcome
- Singapore2 studies, 2 as a primary outcome
- Sweden2 studies, 1 as a primary outcome
- Brazil1 studies, 0 as a primary outcome
- Chile1 studies, 1 as a primary outcome
20 countries in all. A study with sites in several counts in each; 4 list no site.
Reported results
Completed studies with results posted on ClinicalTrials.gov, a results paper the registry links to the study, or both.
Completed aging, frailty and exercise studies that name the N-Back Task: 20 of 44, 45%
Every completed study with a cognitive outcome: 3,626 of 7,953, 46%
| Results | Completed aging, frailty and exercise studies that name the N-Back Task | Every completed study |
|---|---|---|
| Results on ClinicalTrials.gov and a paper | 0, 0% | 776, 10% |
| Results on ClinicalTrials.gov only | 4, 9% | 1,139, 14% |
| A results paper only | 16, 36% | 1,711, 22% |
| Neither | 24, 55% | 4,327, 54% |
The 68 studies
68 studies match. 39 name the N-Back Task in a primary outcome. Median size 68 participants. Median time to the primary outcome: 8 weeks.
Loading 68 studies; the filters turn on when they arrive.
2026 is partly planned starts. Not shown: 1 planned to start after 2026.
Show as a table
| Start year | Studies | As a primary outcome |
|---|---|---|
| 2000 | 0 | 0 |
| 2001 | 0 | 0 |
| 2002 | 1 | 0 |
| 2003 | 0 | 0 |
| 2004 | 0 | 0 |
| 2005 | 0 | 0 |
| 2006 | 0 | 0 |
| 2007 | 0 | 0 |
| 2008 | 1 | 0 |
| 2009 | 0 | 0 |
| 2010 | 0 | 0 |
| 2011 | 0 | 0 |
| 2012 | 1 | 0 |
| 2013 | 0 | 0 |
| 2014 | 2 | 0 |
| 2015 | 5 | 2 |
| 2016 | 1 | 1 |
| 2017 | 1 | 1 |
| 2018 | 6 | 4 |
| 2019 | 5 | 2 |
| 2020 | 2 | 2 |
| 2021 | 7 | 4 |
| 2022 | 11 | 9 |
| 2023 | 9 | 4 |
| 2024 | 5 | 3 |
| 2025 | 4 | 2 |
| 2026 | 6 | 4 |
Library tests named most
Conditions
Phases
Participants
Lead sponsor: industry 3, other 65. Interventional 64, observational 4.
As a primary outcomeSecondary or other outcomeThe N-Back Task
The studies, newest registration first
Each number opens the study's record on ClinicalTrials.gov.
| Study | Start | Phase | Conditions | Participants | Lead sponsor | Status | Library tests named, with the latest time point |
|---|---|---|---|---|---|---|---|
| NCT07861867 | Start2027 | PhasePhase 2 | ConditionsStroke, Aging, frailty and exercise | Participants60 | Lead sponsorOther | StatusNot yet recruiting | Library tests named
|
| NCT07809750 | Start2026 | PhaseNot applicable | ConditionsAging, frailty and exercise | Participants700 | Lead sponsorOther | StatusNot yet recruiting | Library tests named
|
| NCT07749144 | Start2026 | PhaseNot applicable | ConditionsAging, frailty and exercise | Participants120 | Lead sponsorOther | StatusCompleted | Library tests named
|
| NCT07710339 | Start2026 | PhaseNot applicable | ConditionsAging, frailty and exercise | Participants30 | Lead sponsorOther | StatusNot yet recruiting | Library tests named
|
| NCT07695246 | Start2026 | PhaseNot applicable | ConditionsAging, frailty and exercise, Sleep and sleep disorders | Participants183 | Lead sponsorOther | StatusRecruiting | Library tests named
|
| NCT07560904 | Start2026 | PhaseNot applicable | ConditionsMild cognitive impairment, Aging, frailty and exercise | Participants70 | Lead sponsorOther | StatusRecruiting | Library tests named
|
| NCT07443189 | Start2021 | PhaseNot applicable | ConditionsHealthy volunteers, Aging, frailty and exercise | Participants233 | Lead sponsorOther | StatusCompleted | Library tests named
|
| NCT07209683 | Start2025 | PhaseNot applicable | ConditionsAging, frailty and exercise | Participants30 | Lead sponsorOther | StatusRecruiting | Library tests named
|
| NCT07173543 | Start2025 | PhaseNot applicable | ConditionsAging, frailty and exercise, Obesity and diabetes | Participants80 | Lead sponsorOther | StatusRecruiting | Library tests named
|
| NCT06991764 | Start2025 | PhaseNot applicable | ConditionsAging, frailty and exercise | Participants120 | Lead sponsorOther | StatusNot yet recruiting | Library tests named
|
| NCT06817681 | Start2025 | PhaseNot applicable | ConditionsAging, frailty and exercise | Participants32 | Lead sponsorOther | StatusActive, not recruiting | Library tests named
|
| NCT06704425 | Start2024 | PhaseObservational | ConditionsAging, frailty and exercise, Pain and fatigue | Participants80 | Lead sponsorOther | StatusStatus unknown | Library tests named
|
| NCT06703424 | Start2024 | PhaseNot applicable | ConditionsAging, frailty and exercise | Participants23 | Lead sponsorOther | StatusCompleted | Library tests named
|
| NCT06700187 | Start2024 | PhaseNot applicable | ConditionsAging, frailty and exercise | Participants33 | Lead sponsorOther | StatusRecruiting | Library tests named
|
| NCT06563453 | Start2022 | PhaseNot applicable | ConditionsDementia and Alzheimer's, Mild cognitive impairment, Aging, frailty and exercise | Participants55 | Lead sponsorOther | StatusCompleted | Library tests named
|
| NCT06491264 | Start2026 | PhaseNot applicable | ConditionsHealthy volunteers, Aging, frailty and exercise | ParticipantsNot given | Lead sponsorOther | StatusStopped early | Library tests named
|
| NCT06254638 | Start2023 | PhaseNot applicable | ConditionsAging, frailty and exercise | Participants900 | Lead sponsorOther | StatusStatus unknown | Library tests named
|
| NCT06235840 | Start2018 | PhaseNot applicable | ConditionsDementia and Alzheimer's, Aging, frailty and exercise | Participants117 | Lead sponsorOther | StatusCompleted | Library tests named
|
| NCT06019195 | Start2024 | PhaseNot applicable | ConditionsAging, frailty and exercise | Participants32 | Lead sponsorOther | StatusCompleted | Library tests named
|
| NCT05974605 | Start2022 | PhaseNot applicable | ConditionsHealthy volunteers, Aging, frailty and exercise | Participants16 | Lead sponsorOther | StatusCompleted | Library tests named
|
| NCT05891054 | Start2023 | PhaseNot applicable | ConditionsAging, frailty and exercise | Participants292 | Lead sponsorOther | StatusCompleted | Library tests named
|
| NCT05861726 | Start2023 | PhaseNot applicable | ConditionsAging, frailty and exercise | Participants38 | Lead sponsorOther | StatusStatus unknown | Library tests named
|
| NCT05801042 | Start2023 | PhaseNot applicable | ConditionsAging, frailty and exercise | Participants91 | Lead sponsorOther | StatusCompleted | Library tests named
|
| NCT05777863 | Start2022 | PhaseNot applicable | ConditionsAging, frailty and exercise | Participants102 | Lead sponsorOther | StatusCompleted | Library tests named
|
| NCT05722860 | Start2024 | PhasePhase 1 | ConditionsAging, frailty and exercise | Participants20 | Lead sponsorOther | StatusCompleted | Library tests named
|
Questions, answered from the data
How many aging, frailty and exercise trials use the N-Back Task?
68 registered aging, frailty and exercise studies on ClinicalTrials.gov name it in an outcome measure, 39 of them in a primary outcome: 5% of the condition's 1,398 studies with a cognitive outcome, against 5% of all of them. It is the 7th most named test in aging, frailty and exercise trials.
Which tests do aging, frailty and exercise trials use with the N-Back Task?
The Stroop Color-Word Test (17 studies), the Trail Making Test (13 studies) and Symbol Coding (12 studies).
When do aging, frailty and exercise trials measure the N-Back Task?
Half of the primary outcomes that name the N-Back Task are measured within 8 weeks of the start, and the middle half from 1 week to 6 months. 37 primary outcomes give a duration.
How many completed aging, frailty and exercise trials that use the N-Back Task have reported results?
20 of the 44 completed studies that name it, 45%, have reported results: 4 posted them on ClinicalTrials.gov, 16 have a results paper linked to the registry record, and 0 did both. The other 24 show neither. Of all completed studies with a cognitive outcome, 46% have reported results.
How the studies are counted
For each test family, the census runs ClinicalTrials.gov's own outcome search for the family's names and reads every study first posted by the day the family was counted. These studies were read on 10 November 2026. A study counts once on a page, however many tests it names. Counts for a test cover every version of the task under any of its names, so a page can count studies that used a commercial version.
The census adds two things to each record and changes nothing in it: which outcome list names the test (primary, then secondary, then other), and the condition groups, matched on the study's condition names and MeSH terms. A study can fall in several groups; one whose only condition is cognitive impairment or decline falls in “Cognitive impairment and decline”. Studies that name only instruments outside the library count in every total and share but are not listed.
A second read on 10 November 2026 added each study's overall status, whether results are posted, its intervention types, the countries of its sites and the time frame of the outcome that names each test. A time frame counts by the latest time point it names: “Baseline, 12 and 24 weeks” is 24 weeks, a single visit is within a day, and one that names no duration, such as “end of treatment”, is left out of the timings.
A third read on 10 November 2026 added the papers the registry links to each study: those its sponsor lists as reporting results, and those PubMed links to it through the study's NCT number. A study has a results paper when one of them came out in or after the month of its primary completion and PubMed does not class it as a protocol, review or comment. A paper that never gives the NCT number is not linked, so some studies counted as reporting neither did publish.
Source: ClinicalTrials.gov, a database of the U.S. National Library of Medicine, which does not endorse these pages. Every study line is in the data release 2.1.0, and the explorer's own file is clinical-trials-studies.json.
The census counts 1-Back Task and 2-Back Task as one test family, so this page counts their studies together.
Run the N-Back Task in your trial
Choose tests with a record in registered trials, and run them in a browser at every site, on the same version each visit.