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Clinical trials data

AX Continuous Performance Test in clinical trials: 191 registered studies

Every registered study on ClinicalTrials.gov that names the AX Continuous Performance Test in an outcome measure: the conditions it is used in, how often it is a primary outcome, the tests it is named with, and how large the studies are.

Registered studies name it in an outcome measure
191
Name it in a primary outcome, 17%
33 of 191
Against similar tests
Of studies started 2021 to 2025 name it, against 1.1% in 2016 to 2020
1.0%
By year
Median participants per study
58
By phase
Try the AX Continuous Performance Test

The conditions it is used in

Each study counted once in each condition group it falls in.
  1. ADHD36 studies, 0 as a primary outcome

  2. Schizophrenia and psychosis32 studies, 20 as a primary outcome

  3. Substance use and addiction24 studies, 1 as a primary outcome

  4. Depression and bipolar disorder23 studies, 6 as a primary outcome

  5. Anxiety, PTSD and OCD16 studies, 1 as a primary outcome

  6. Brain injury and concussion10 studies, 0 as a primary outcome

  7. Healthy volunteers9 studies, 3 as a primary outcome

  8. Aging, frailty and exercise8 studies, 1 as a primary outcome

  9. Mild cognitive impairment7 studies, 1 as a primary outcome

  10. Sleep and sleep disorders6 studies, 0 as a primary outcome

  11. Stroke5 studies, 0 as a primary outcome

  12. Cognitive impairment and decline5 studies, 0 as a primary outcome

  13. Dementia and Alzheimer's4 studies, 2 as a primary outcome

  14. Cancer4 studies, 0 as a primary outcome

  15. Parkinson's disease2 studies, 0 as a primary outcome

  16. Obesity and diabetes2 studies, 0 as a primary outcome

  17. Autism2 studies, 0 as a primary outcome

  18. Pain and fatigue2 studies, 0 as a primary outcome

  19. Multiple sclerosis1 study, 0 as a primary outcome

  20. COVID-19 and long COVID1 study, 0 as a primary outcome

  21. Delirium, surgery and intensive care1 study, 1 as a primary outcome

  22. Lung disease1 study, 0 as a primary outcome

  23. Other conditions30 studies, 5 as a primary outcome

A test as a primary outcomeOnly in secondary or other outcomes

How often it is a primary outcome

The AX Continuous Performance Test is a primary outcome in 17% of its studies. Across the 30 executive function tests with a page here, the median is 37%.
  1. Cue Reactivity Task56% of 188 studies

  2. Stroop Color-Word Test41% of 1,929 studies

  3. Tower Planning40% of 247 studies

  4. Task Switching Test40% of 334 studies

  5. Dimensional Change Card Sort38% of 214 studies

  6. Verbal Fluency37% of 1,745 studies

  7. Delay Discounting36% of 257 studies

  8. Clock Drawing Task35% of 281 studies

  9. Matrix Reasoning35% of 272 studies

  10. Card Sorting Test (Berg)34% of 411 studies

  11. Trail Making Test31% of 2,293 studies

  12. AX Continuous Performance Test17% of 191 studies

Studies by start year

1.0% of the registered studies that started in 2021 to 2025 name it, against 1.1% of those that started in 2016 to 2020. 2026 is partly planned starts.
02000: 0 studies, 0 with a test as a primary outcome20002001: 0 studies, 0 with a test as a primary outcome2002: 0 studies, 0 with a test as a primary outcome2003: 2 studies, 0 with a test as a primary outcome2004: 1 studies, 0 with a test as a primary outcome2005: 3 studies, 1 with a test as a primary outcome20052006: 2 studies, 1 with a test as a primary outcome2007: 1 studies, 0 with a test as a primary outcome2008: 4 studies, 0 with a test as a primary outcome2009: 3 studies, 0 with a test as a primary outcome2010: 2 studies, 0 with a test as a primary outcome20102011: 6 studies, 1 with a test as a primary outcome2012: 4 studies, 0 with a test as a primary outcome2013: 8 studies, 1 with a test as a primary outcome2014: 10 studies, 3 with a test as a primary outcome2015: 12 studies, 0 with a test as a primary outcome20152016: 8 studies, 4 with a test as a primary outcome2017: 12 studies, 1 with a test as a primary outcome2018: 10 studies, 1 with a test as a primary outcome2019: 11 studies, 3 with a test as a primary outcome2020: 7 studies, 2 with a test as a primary outcome20202021: 17 studies, 2 with a test as a primary outcome2022: 9 studies, 2 with a test as a primary outcome2023: 15 studies, 3 with a test as a primary outcome2024: 16 studies, 2 with a test as a primary outcome2025: 12 studies, 3 with a test as a primary outcome20252026: 12 studies, 2 with a test as a primary outcome

A test as a primary outcomeOnly in secondary or other outcomes

Show as a table
Registered studies by start year
Start yearStudiesA test as a primary outcome
200000
200100
200200
200320
200410
200531
200621
200710
200840
200930
201020
201161
201240
201381
2014103
2015120
201684
2017121
2018101
2019113
202072
2021172
202292
2023153
2024162
2025123
2026122

Phases and study sizes

By phase

  • Early phase 113 studies, 1 as a primary outcome
  • Phase 19 studies, 0 as a primary outcome
  • Phase 1/22 studies, 0 as a primary outcome
  • Phase 219 studies, 4 as a primary outcome
  • Phase 38 studies, 2 as a primary outcome
  • Phase 49 studies, 2 as a primary outcome
  • Not applicable113 studies, 20 as a primary outcome
  • Observational18 studies, 4 as a primary outcome

Participants per study

102050100200
  • Early phase 144 median, 23 to 103
  • Phase 236 median, 23 to 65
  • Not applicable60 median, 30 to 100
  • Observational90 median, 29 to 270
Participants per study. The bar spans the middle half of the studies in each phase, the mark is the median, and the axis is logarithmic. Phases with fewer than 10 studies that give a size are left out.
Show as a table
Participants per study that names the AX Continuous Performance Test, by phase
PhaseStudies with a sizeMedianMiddle half
Early phase 1124423 to 103
Phase 2193623 to 65
Not applicable1126030 to 100
Observational189029 to 270

When trials measure it

Half of the primary outcomes that name the AX Continuous Performance Test are measured within 4 weeks of the start, and the middle half from the first day to 5 months. 30 primary outcomes give a duration.

Latest time point of each outcome

  • Within a day11 outcomes, 9 as a primary outcome
  • Up to 4 weeks12 outcomes, 7 as a primary outcome
  • 1 to 3 months9 outcomes, 6 as a primary outcome
  • 3 to 6 months6 outcomes, 6 as a primary outcome
  • 6 to 12 months2 outcomes, 0 as a primary outcome
  • Over 2 years3 outcomes, 2 as a primary outcome
  • No duration given3 outcomes, 3 as a primary outcome

A test as a primary outcomeOnly in secondary or other outcomes

43 of the 46 outcome measures give a duration. A single visit counts as within a day.

Status, results, interventions and countries

Status

  • Recruiting32 studies, 9 as a primary outcome
  • Not yet recruiting8 studies, 1 as a primary outcome
  • Active, not recruiting11 studies, 2 as a primary outcome
  • Completed106 studies, 18 as a primary outcome
  • Stopped early15 studies, 1 as a primary outcome
  • Status unknown19 studies, 2 as a primary outcome

What they test

  • Behavioral61 studies, 9 as a primary outcome
  • Drug64 studies, 9 as a primary outcome
  • Device39 studies, 11 as a primary outcome
  • Dietary supplement16 studies, 2 as a primary outcome
  • Procedure6 studies, 0 as a primary outcome
  • Diagnostic test3 studies, 0 as a primary outcome
  • Biological2 studies, 0 as a primary outcome
  • Combination product2 studies, 0 as a primary outcome
  • Genetic2 studies, 0 as a primary outcome
  • Other32 studies, 3 as a primary outcome
  • None given6 studies, 3 as a primary outcome

Intervention types as registered. A study can list several; observational studies often list none.

Where their sites are

  • United States127 studies, 26 as a primary outcome
  • Canada13 studies, 1 as a primary outcome
  • United Kingdom11 studies, 0 as a primary outcome
  • France8 studies, 0 as a primary outcome
  • Germany6 studies, 3 as a primary outcome
  • Sweden3 studies, 0 as a primary outcome
  • Denmark2 studies, 1 as a primary outcome
  • Norway2 studies, 1 as a primary outcome
  • Spain2 studies, 1 as a primary outcome
  • Switzerland2 studies, 0 as a primary outcome
  • Taiwan2 studies, 0 as a primary outcome
  • Australia1 studies, 0 as a primary outcome

23 countries in all. A study with sites in several counts in each; 9 list no site.

Reported results

Completed studies with results posted on ClinicalTrials.gov, a results paper the registry links to the study, or both.

Completed studies that name the AX Continuous Performance Test: 51 of 106, 48%

Every completed study with a cognitive outcome: 3,626 of 7,953, 46%

Completed studies that name the AX Continuous Performance Test and every completed study, by how they reported results
ResultsCompleted studies that name the AX Continuous Performance TestEvery completed study
Results on ClinicalTrials.gov and a paper10, 9%776, 10%
Results on ClinicalTrials.gov only27, 25%1,139, 14%
A results paper only14, 13%1,711, 22%
Neither55, 52%4,327, 54%

Tests named in the same studies

The library tests that studies naming the AX Continuous Performance Test name most often beside it.
  1. 1

    Continuous Performance Test181 studies, 82 as a primary outcome

  2. 2

    N-Back Task38 studies, 20 as a primary outcome

  3. 3

    Verbal Learning27 studies, 13 as a primary outcome

  4. 4

    Digit Span Test26 studies, 11 as a primary outcome

  5. 5

    Go/No-Go Task25 studies, 16 as a primary outcome

  6. 6

    Trail Making Test20 studies, 9 as a primary outcome

  7. 7

    Verbal Fluency16 studies, 5 as a primary outcome

  8. 8

    Stop-Signal Task15 studies, 6 as a primary outcome

  9. 9

    Stroop Color-Word Test13 studies, 7 as a primary outcome

  10. 10

    Symbol Coding11 studies, 7 as a primary outcome

A test as a primary outcomeOnly in secondary or other outcomes

Compared over time

Studies per start year for the AX Continuous Performance Test and the tests named with it most. Add or remove tests to compare.
AX Continuous Performance Test187 studies, 2000 to 2026
01002002000201020202026
Continuous Performance Test632 studies, 2000 to 2026
01002002000201020202026
N-Back Task787 studies, 2000 to 2026
01002002000201020202026
Verbal Learning1,819 studies, 2000 to 2026
01002002000201020202026

The panel's testThe other tests chosenEvery panel has the same scale. 2026 is partly planned starts.

Show as a table
Registered studies per start year that name each test
Start yearAX Continuous Performance TestContinuous Performance TestN-Back TaskVerbal Learning
20000101
20010105
20020328
200326214
200416014
200538417
200628313
20071111022
20084101028
2009316528
20102141142
20116202033
20124171442
20138202353
201410272582
201512242591
20168323298
2017123751107
201810375492
2019114159122
20207293076
2021173970137
202293662138
2023156571157
2024165369144
2025124167132
2026123068123

Explore the 191 studies

Filter by condition, phase, sponsor, status, country, intervention, outcome list, size and start year. Each study links to its record on ClinicalTrials.gov.
TestThe AX Continuous Performance Test

191 studies match. 33 name the AX Continuous Performance Test in a primary outcome. Median size 58 participants. Median time to the primary outcome: 4 weeks.

Loading 191 studies; the filters turn on when they arrive.

By start year
051015202000: 0 studies, 0 naming the AX Continuous Performance Test in a primary outcome20002001: 0 studies, 0 naming the AX Continuous Performance Test in a primary outcome2002: 0 studies, 0 naming the AX Continuous Performance Test in a primary outcome2003: 2 studies, 0 naming the AX Continuous Performance Test in a primary outcome2004: 1 studies, 0 naming the AX Continuous Performance Test in a primary outcome2005: 3 studies, 1 naming the AX Continuous Performance Test in a primary outcome20052006: 2 studies, 1 naming the AX Continuous Performance Test in a primary outcome2007: 1 studies, 0 naming the AX Continuous Performance Test in a primary outcome2008: 4 studies, 0 naming the AX Continuous Performance Test in a primary outcome2009: 3 studies, 0 naming the AX Continuous Performance Test in a primary outcome2010: 2 studies, 0 naming the AX Continuous Performance Test in a primary outcome20102011: 6 studies, 1 naming the AX Continuous Performance Test in a primary outcome2012: 4 studies, 0 naming the AX Continuous Performance Test in a primary outcome2013: 8 studies, 1 naming the AX Continuous Performance Test in a primary outcome2014: 10 studies, 3 naming the AX Continuous Performance Test in a primary outcome2015: 12 studies, 0 naming the AX Continuous Performance Test in a primary outcome20152016: 8 studies, 4 naming the AX Continuous Performance Test in a primary outcome2017: 12 studies, 1 naming the AX Continuous Performance Test in a primary outcome2018: 10 studies, 1 naming the AX Continuous Performance Test in a primary outcome2019: 11 studies, 3 naming the AX Continuous Performance Test in a primary outcome2020: 7 studies, 2 naming the AX Continuous Performance Test in a primary outcome20202021: 17 studies, 2 naming the AX Continuous Performance Test in a primary outcome2022: 9 studies, 2 naming the AX Continuous Performance Test in a primary outcome2023: 15 studies, 3 naming the AX Continuous Performance Test in a primary outcome2024: 16 studies, 2 naming the AX Continuous Performance Test in a primary outcome2025: 12 studies, 3 naming the AX Continuous Performance Test in a primary outcome20252026: 12 studies, 2 naming the AX Continuous Performance Test in a primary outcome

2026 is partly planned starts. Not shown: 2 that started before 2000 and 2 planned to start after 2026.

Show as a table
Matching studies by start year
Start yearStudiesAs a primary outcome
200000
200100
200200
200320
200410
200531
200621
200710
200840
200930
201020
201161
201240
201381
2014103
2015120
201684
2017121
2018101
2019113
202072
2021172
202292
2023153
2024162
2025123
2026122

Library tests named most

  • AX Continuous Performance Test191 studies, 33 as a primary outcome
  • Continuous Performance Test181 studies, 82 as a primary outcome
  • N-Back Task38 studies, 20 as a primary outcome
  • Verbal Learning27 studies, 13 as a primary outcome
  • Digit Span Test26 studies, 11 as a primary outcome
  • Go/No-Go Task25 studies, 16 as a primary outcome
  • Trail Making Test20 studies, 9 as a primary outcome
  • Verbal Fluency16 studies, 5 as a primary outcome
  • Stop-Signal Task15 studies, 6 as a primary outcome
  • Stroop Color-Word Test13 studies, 7 as a primary outcome

Largest condition groups

Phases

Participants

Lead sponsor: industry 17, other 174. Interventional 173, observational 18.

As a primary outcomeSecondary or other outcomeThe AX Continuous Performance Test

The studies, newest registration first

Each number opens the study's record on ClinicalTrials.gov.

Registered studies that match the filters, newest registration first, with the library tests each one names and the outcome list that names them.
StudyStartPhaseConditionsParticipantsLead sponsorStatusLibrary tests named, with the latest time point
NCT07900451Start2026PhaseObservationalConditionsADHDParticipants90Lead sponsorOtherStatusRecruitingLibrary tests named
  • Continuous Performance TestSecondarysame day
  • AX Continuous Performance TestWording unclear
NCT07900048Start2026PhaseNot applicableConditionsADHDParticipants100Lead sponsorOtherStatusNot yet recruitingLibrary tests named
  • Continuous Performance TestPrimary16 weeks
  • Tower PlanningPrimary16 weeks
  • AX Continuous Performance TestWording unclear
NCT07852052Start2026PhaseObservationalConditionsSubstance use and addiction, Sleep and sleep disordersParticipants34Lead sponsorOtherStatusNot yet recruitingLibrary tests named
  • Continuous Performance TestPrimary13 weeks
  • AX Continuous Performance TestWording unclear
NCT07845409Start2027PhaseNot applicableConditionsDepression and bipolar disorderParticipants138Lead sponsorOtherStatusNot yet recruitingLibrary tests named
  • Trail Making TestPrimary10 weeks
  • Go/No-Go TaskPrimary10 weeks
  • Continuous Performance TestPrimary10 weeks
  • AX Continuous Performance TestPrimary10 weeks
  • Monetary Incentive DelayPrimary10 weeks
  • Affective Go/No-GoPrimary10 weeks
NCT07834203Start2025PhaseObservationalConditionsSchizophrenia and psychosis, Depression and bipolar disorderParticipants500Lead sponsorOtherStatusRecruitingLibrary tests named
  • Continuous Performance TestWording unclear
  • Matrix ReasoningSecondary8 weeks
  • AX Continuous Performance TestPrimary8 weeks
  • Word Pair LearningSecondary8 weeks
  • Four-Armed BanditPrimary8 weeks
NCT07767617Start2026PhaseNot applicableConditionsADHD, Sleep and sleep disordersParticipants150Lead sponsorOtherStatusNot yet recruitingLibrary tests named
  • Digit Span TestSecondary6 months
  • Go/No-Go TaskSecondary4 weeks
  • Continuous Performance TestSecondary6 months
  • Stop-Signal TaskSecondary4 weeks
  • Delay DiscountingSecondary6 months
  • AX Continuous Performance TestWording unclear
  • Balloon RiskSecondary4 weeks
  • Beads TaskSecondary6 months
NCT07693686Start2027PhaseNot applicableConditionsAnxiety, PTSD and OCDParticipants176Lead sponsorOtherStatusNot yet recruitingLibrary tests named
  • Verbal LearningOther outcome10 weeks
  • Verbal FluencyOther outcome10 weeks
  • Digit Span TestOther outcome10 weeks
  • Continuous Performance TestOther outcome10 weeks
  • Choice Reaction TimeOther outcome10 weeks
  • AX Continuous Performance TestOther outcome10 weeks
  • Letter-Number Sequencing TaskOther outcome10 weeks
NCT07587957Start2026PhaseNot applicableConditionsCancerParticipants40Lead sponsorOtherStatusRecruitingLibrary tests named
  • Trail Making TestSecondary4 weeks
  • Verbal LearningOther outcome4 weeks
  • N-Back TaskSecondary4 weeks
  • Continuous Performance TestSecondary4 weeks
  • AX Continuous Performance TestSecondary4 weeks
NCT07576413Start2018PhaseNot applicableConditionsOther conditionsParticipants31Lead sponsorOtherStatusCompletedLibrary tests named
  • Continuous Performance TestSecondarysame day
  • Paced Visual Serial Addition TestSecondarysame day
  • Eriksen Flanker TaskSecondarysame day
  • AX Continuous Performance TestWording unclear
  • Arithmetic Fluency TaskSecondarysame day
NCT07512284Start2026PhasePhase 2ConditionsDepression and bipolar disorderParticipants120Lead sponsorOtherStatusRecruitingLibrary tests named
  • Continuous Performance TestSecondary4 weeks
  • Eriksen Flanker TaskSecondary4 weeks
  • AX Continuous Performance TestWording unclear
  • Delayed Match-to-SampleOther outcome4 weeks
NCT07452562Start2026PhaseNot applicableConditionsMultiple sclerosisParticipants60Lead sponsorOtherStatusRecruitingLibrary tests named
  • Trail Making TestSecondary12 weeks
  • Stroop Color-Word TestSecondary12 weeks
  • Symbol CodingSecondary12 weeks
  • Continuous Performance TestSecondary12 weeks
  • AX Continuous Performance TestWording unclear
NCT07443189Start2021PhaseNot applicableConditionsHealthy volunteers, Aging, frailty and exerciseParticipants233Lead sponsorOtherStatusCompleted

Paper

Library tests named
  • Digit Span TestPrimary6 months
  • N-Back TaskPrimary6 months
  • Continuous Performance TestPrimary6 months
  • Picture Naming TestPrimary6 months
  • Eriksen Flanker TaskPrimary6 months
  • Task Switching TestPrimary6 months
  • AX Continuous Performance TestWording unclear
  • Attention Network TestPrimary6 months
  • Posner CueingPrimary6 months
NCT07389447Start2024PhaseNot applicableConditionsStrokeParticipants20Lead sponsorOtherStatusActive, not recruitingLibrary tests named
  • N-Back TaskSecondary3 days
  • Continuous Performance TestSecondary3 days
  • AX Continuous Performance TestWording unclear
  • Word Pair LearningSecondary3 days
NCT07331077Start2026PhaseNot applicableConditionsCancerParticipants10Lead sponsorOtherStatusNot yet recruitingLibrary tests named
  • Stroop Color-Word TestPrimary6 months
  • Verbal LearningPrimary6 months
  • Continuous Performance TestPrimary6 months
  • Choice Reaction TimePrimary6 months
  • AX Continuous Performance TestWording unclear
NCT07263022Start2026PhasePhase 3ConditionsSchizophrenia and psychosis, Depression and bipolar disorderParticipants24Lead sponsorOtherStatusRecruitingLibrary tests named
  • Symbol CodingPrimarysame day
  • Matrix ReasoningPrimarysame day
  • AX Continuous Performance TestPrimary1 week
  • Word Pair LearningPrimarysame day
  • Four-Armed BanditPrimary1 week
NCT07231497Start2025PhasePhase 3ConditionsSchizophrenia and psychosis, Healthy volunteersParticipants103Lead sponsorOtherStatusRecruitingLibrary tests named
  • Symbol CodingPrimarysame day
  • Matrix ReasoningPrimarysame day
  • AX Continuous Performance TestPrimary1 week
  • Word Pair LearningPrimarysame day
  • Four-Armed BanditPrimary1 week
NCT07203092Start2025PhaseNot applicableConditionsADHDParticipants140Lead sponsorOtherStatusRecruitingLibrary tests named
  • Continuous Performance TestPrimary2 weeks
  • AX Continuous Performance TestWording unclear
NCT07147894Start2025PhaseNot applicableConditionsADHDParticipants780Lead sponsorOtherStatusRecruitingLibrary tests named
  • N-Back TaskOther outcome7 months
  • Continuous Performance TestPrimary7 months
  • Eriksen Flanker TaskPrimary7 months
  • Matrix ReasoningSecondary7 months
  • AX Continuous Performance TestWording unclear
  • Letter-Number Sequencing TaskPrimary7 months
NCT07137676Start2023PhaseNot applicableConditionsMild cognitive impairmentParticipants60Lead sponsorOtherStatusCompletedLibrary tests named
  • Continuous Performance TestPrimary2 weeks
  • AX Continuous Performance TestPrimary2 weeks
NCT07050316Start2025PhasePhase 1ConditionsOther conditionsParticipants48Lead sponsorOtherStatusCompleted

Paper

Library tests named
  • Symbol CodingOther outcome2 days
  • N-Back TaskOther outcome2 days
  • Continuous Performance TestOther outcome2 days
  • AX Continuous Performance TestWording unclear
NCT07040904Start2024PhaseNot applicableConditionsDementia and Alzheimer'sParticipants60Lead sponsorOtherStatusRecruitingLibrary tests named
  • Continuous Performance TestWording unclear
  • AX Continuous Performance TestPrimary
NCT07019402Start2025PhaseNot applicableConditionsCognitive impairment and declineParticipants60Lead sponsorOtherStatusCompletedLibrary tests named
  • Go/No-Go TaskSecondary8 weeks
  • Continuous Performance TestSecondary8 weeks
  • AX Continuous Performance TestWording unclear
  • Gradual-Onset Continuous Performance TaskSecondary8 weeks
NCT07006935Start2026PhaseNot applicableConditionsSchizophrenia and psychosisParticipants30Lead sponsorOtherStatusRecruitingLibrary tests named
  • N-Back TaskPrimary6 months
  • Continuous Performance TestPrimary6 months
  • AX Continuous Performance TestPrimary6 months
  • Emoji Emotion RecognitionSecondary6 months
  • Indirect Hints TaskSecondary6 months
NCT06944847Start2025PhaseNot applicableConditionsOther conditionsParticipants64Lead sponsorOtherStatusRecruitingLibrary tests named
  • N-Back TaskPrimarysame day
  • Continuous Performance TestPrimarysame day
  • Stop-Signal TaskPrimarysame day
  • AX Continuous Performance TestWording unclear
  • Purchase TaskPrimarysame day
  • Spatial Working MemoryPrimarysame day
NCT06854224Start2025PhasePhase 2ConditionsDepression and bipolar disorderParticipants30Lead sponsorOtherStatusRecruitingLibrary tests named
  • Continuous Performance TestSecondary5 weeks
  • AX Continuous Performance TestWording unclear
  • Gradual-Onset Continuous Performance TaskSecondary5 weeks
  • Point Subtraction Aggression TaskSecondary5 weeks

Page 1 of 8

Questions, answered from the data

How many clinical trials use the AX Continuous Performance Test?

191 registered studies on ClinicalTrials.gov name it in an outcome measure, 33 of them in a primary outcome.

In which conditions do trials use the AX Continuous Performance Test?

Most often in ADHD (36), schizophrenia and psychosis (32) and substance use and addiction (24).

Do new trials use the AX Continuous Performance Test more or less?

1.0% of the studies that started in 2021 to 2025 name it, against 1.1% of those that started in 2016 to 2020: a share 9% smaller.

Which tests do trials use with the AX Continuous Performance Test?

The Continuous Performance Test (181 studies), the N-Back Task (38 studies) and Verbal Learning (27 studies).

How many participants do phase 2 trials that use the AX Continuous Performance Test enroll?

Half of the phase 2 studies that name it enroll 36 participants or fewer, and the middle half enroll 23 to 65. 19 of them give a size.

When do trials measure the AX Continuous Performance Test?

Half of the primary outcomes that name the AX Continuous Performance Test are measured within 4 weeks of the start, and the middle half from the first day to 5 months. 30 primary outcomes give a duration.

How many completed trials that use the AX Continuous Performance Test have reported results?

51 of the 106 completed studies that name it, 48%, have reported results: 37 posted them on ClinicalTrials.gov, 24 have a results paper linked to the registry record, and 10 did both. The other 55 show neither. Of all completed studies with a cognitive outcome, 46% have reported results.

More on tests in clinical trials

  • AX Continuous Performance Test: what it measures, its scores, and a version to try
  • All 101 tests in clinical trials
  • Cognitive tests by condition
  • Every registered study, by test, condition, phase and year

How the studies are counted

For each test family, the census runs ClinicalTrials.gov's own outcome search for the family's names and reads every study first posted by the day the family was counted. These studies were read on 10 November 2026. A study counts once on a page, however many tests it names. Counts for a test cover every version of the task under any of its names, so a page can count studies that used a commercial version.

The census adds two things to each record and changes nothing in it: which outcome list names the test (primary, then secondary, then other), and the condition groups, matched on the study's condition names and MeSH terms. A study can fall in several groups; one whose only condition is cognitive impairment or decline falls in “Cognitive impairment and decline”. Studies that name only instruments outside the library count in every total and share but are not listed.

A second read on 10 November 2026 added each study's overall status, whether results are posted, its intervention types, the countries of its sites and the time frame of the outcome that names each test. A time frame counts by the latest time point it names: “Baseline, 12 and 24 weeks” is 24 weeks, a single visit is within a day, and one that names no duration, such as “end of treatment”, is left out of the timings.

A third read on 10 November 2026 added the papers the registry links to each study: those its sponsor lists as reporting results, and those PubMed links to it through the study's NCT number. A study has a results paper when one of them came out in or after the month of its primary completion and PubMed does not class it as a protocol, review or comment. A paper that never gives the NCT number is not linked, so some studies counted as reporting neither did publish.

Source: ClinicalTrials.gov, a database of the U.S. National Library of Medicine, which does not endorse these pages. Every study line is in the data release 2.1.0, and the explorer's own file is clinical-trials-studies.json.

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