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  1. Home
  2. /Data
  3. /Clinical trials
  4. /Conditions
  5. /Obesity and diabetes
  6. /Symbol Coding

Clinical trials data

Symbol Coding in obesity and diabetes trials: 59 registered studies

Every registered obesity and diabetes study on ClinicalTrials.gov that names Symbol Coding in an outcome measure: how often it is a primary outcome, the tests named with it, how large the studies are and when they measure it.

Registered obesity and diabetes studies name it in an outcome measure
59
Name it in a primary outcome, 46%
27 of 59
Of the condition's 627 studies name it, against 9% of all registered studies
9%
Other conditions
Median participants per study
66
By phase
Try the Symbol Key GameTry Symbol Coding

Tests named in the same studies

The library tests that obesity and diabetes studies naming Symbol Coding name most often beside it.
  1. 1

    Trail Making Test26 studies, 13 as a primary outcome

  2. 2

    Verbal Learning22 studies, 14 as a primary outcome

  3. 3

    Digit Span Test17 studies, 11 as a primary outcome

  4. 4

    Stroop Color-Word Test15 studies, 6 as a primary outcome

  5. 5

    Verbal Fluency12 studies, 9 as a primary outcome

  6. 6

    Category Fluency8 studies, 7 as a primary outcome

  7. 7

    Short Story Recall5 studies, 2 as a primary outcome

  8. 8

    Task Switching Test5 studies, 2 as a primary outcome

  9. 9

    Letter-Number Sequencing Task4 studies, 3 as a primary outcome

  10. 10

    Picture Naming Test4 studies, 2 as a primary outcome

A test as a primary outcomeOnly in secondary or other outcomes

Studies by start year

Each study counted once. 2026 is partly planned starts.
02000: 0 studies, 0 with a test as a primary outcome20002001: 0 studies, 0 with a test as a primary outcome2002: 0 studies, 0 with a test as a primary outcome2003: 0 studies, 0 with a test as a primary outcome2004: 0 studies, 0 with a test as a primary outcome2005: 1 studies, 1 with a test as a primary outcome20052006: 0 studies, 0 with a test as a primary outcome2007: 0 studies, 0 with a test as a primary outcome2008: 1 studies, 1 with a test as a primary outcome2009: 2 studies, 0 with a test as a primary outcome2010: 3 studies, 2 with a test as a primary outcome20102011: 1 studies, 0 with a test as a primary outcome2012: 1 studies, 0 with a test as a primary outcome2013: 2 studies, 2 with a test as a primary outcome2014: 0 studies, 0 with a test as a primary outcome2015: 1 studies, 0 with a test as a primary outcome20152016: 2 studies, 1 with a test as a primary outcome2017: 1 studies, 1 with a test as a primary outcome2018: 3 studies, 1 with a test as a primary outcome2019: 5 studies, 1 with a test as a primary outcome2020: 0 studies, 0 with a test as a primary outcome20202021: 4 studies, 2 with a test as a primary outcome2022: 5 studies, 2 with a test as a primary outcome2023: 6 studies, 3 with a test as a primary outcome2024: 9 studies, 2 with a test as a primary outcome2025: 5 studies, 4 with a test as a primary outcome20252026: 6 studies, 4 with a test as a primary outcome

A test as a primary outcomeOnly in secondary or other outcomes

Show as a table
Registered studies by start year
Start yearStudiesA test as a primary outcome
200000
200100
200200
200300
200400
200511
200600
200700
200811
200920
201032
201110
201210
201322
201400
201510
201621
201711
201831
201951
202000
202142
202252
202363
202492
202554
202664

Phases and study sizes

By phase

  • Early phase 11 studies, 0 as a primary outcome
  • Phase 14 studies, 2 as a primary outcome
  • Phase 22 studies, 1 as a primary outcome
  • Phase 2/31 studies, 1 as a primary outcome
  • Phase 31 studies, 0 as a primary outcome
  • Phase 46 studies, 3 as a primary outcome
  • Not applicable37 studies, 15 as a primary outcome
  • Observational7 studies, 5 as a primary outcome

Participants per study

102050100
  • Not applicable40 median, 20 to 99
Participants per study. The bar spans the middle half of the studies in each phase, the mark is the median, and the axis is logarithmic. Phases with fewer than 10 studies that give a size are left out.
Show as a table
Participants per obesity and diabetes study that names Symbol Coding, by phase
PhaseStudies with a sizeMedianMiddle half
Not applicable374020 to 99

When obesity and diabetes trials measure it

Half of the primary outcomes that name Symbol Coding are measured within 12 weeks of the start, and the middle half from the first day to 6 months. 25 primary outcomes give a duration.

Latest time point of each outcome

  • Within a day14 outcomes, 8 as a primary outcome
  • Up to 4 weeks7 outcomes, 2 as a primary outcome
  • 1 to 3 months8 outcomes, 5 as a primary outcome
  • 3 to 6 months12 outcomes, 4 as a primary outcome
  • 6 to 12 months7 outcomes, 3 as a primary outcome
  • 1 to 2 years4 outcomes, 2 as a primary outcome
  • Over 2 years4 outcomes, 1 as a primary outcome
  • No duration given3 outcomes, 2 as a primary outcome

A test as a primary outcomeOnly in secondary or other outcomes

56 of the 59 outcome measures give a duration. A single visit counts as within a day.

Status, results, interventions and countries

Status

  • Recruiting8 studies, 6 as a primary outcome
  • Not yet recruiting3 studies, 0 as a primary outcome
  • Active, not recruiting5 studies, 3 as a primary outcome
  • Completed35 studies, 16 as a primary outcome
  • Stopped early3 studies, 2 as a primary outcome
  • Status unknown5 studies, 0 as a primary outcome

What they test

  • Behavioral13 studies, 7 as a primary outcome
  • Drug15 studies, 7 as a primary outcome
  • Device5 studies, 1 as a primary outcome
  • Dietary supplement13 studies, 4 as a primary outcome
  • Procedure2 studies, 0 as a primary outcome
  • Biological1 studies, 0 as a primary outcome
  • Radiation1 studies, 0 as a primary outcome
  • Other21 studies, 11 as a primary outcome
  • None given4 studies, 3 as a primary outcome

Intervention types as registered. A study can list several; observational studies often list none.

Where their sites are

  • United States22 studies, 13 as a primary outcome
  • Denmark9 studies, 4 as a primary outcome
  • Canada7 studies, 1 as a primary outcome
  • China4 studies, 3 as a primary outcome
  • United Kingdom4 studies, 0 as a primary outcome
  • France2 studies, 1 as a primary outcome
  • Germany2 studies, 1 as a primary outcome
  • Italy2 studies, 0 as a primary outcome
  • Mexico2 studies, 1 as a primary outcome
  • Norway2 studies, 0 as a primary outcome
  • Sweden2 studies, 0 as a primary outcome
  • Switzerland2 studies, 0 as a primary outcome

36 countries in all. A study with sites in several counts in each; 0 list no site.

Reported results

Completed studies with results posted on ClinicalTrials.gov, a results paper the registry links to the study, or both.

Completed obesity and diabetes studies that name Symbol Coding: 17 of 35, 49%

Every completed study with a cognitive outcome: 3,626 of 7,953, 46%

Completed obesity and diabetes studies that name Symbol Coding and every completed study, by how they reported results
ResultsCompleted obesity and diabetes studies that name Symbol CodingEvery completed study
Results on ClinicalTrials.gov and a paper4, 11%776, 10%
Results on ClinicalTrials.gov only7, 20%1,139, 14%
A results paper only6, 17%1,711, 22%
Neither18, 51%4,327, 54%

The 59 studies

Filter by phase, sponsor, status, country, intervention, outcome list, size and start year. Each study links to its record on ClinicalTrials.gov.
ConditionObesity and diabetes
TestSymbol Coding

59 studies match. 27 name Symbol Coding in a primary outcome. Median size 66 participants. Median time to the primary outcome: 12 weeks.

Loading 59 studies; the filters turn on when they arrive.

By start year
02.557.5102000: 0 studies, 0 naming Symbol Coding in a primary outcome20002001: 0 studies, 0 naming Symbol Coding in a primary outcome2002: 0 studies, 0 naming Symbol Coding in a primary outcome2003: 0 studies, 0 naming Symbol Coding in a primary outcome2004: 0 studies, 0 naming Symbol Coding in a primary outcome2005: 1 studies, 1 naming Symbol Coding in a primary outcome20052006: 0 studies, 0 naming Symbol Coding in a primary outcome2007: 0 studies, 0 naming Symbol Coding in a primary outcome2008: 1 studies, 1 naming Symbol Coding in a primary outcome2009: 2 studies, 0 naming Symbol Coding in a primary outcome2010: 3 studies, 2 naming Symbol Coding in a primary outcome20102011: 1 studies, 0 naming Symbol Coding in a primary outcome2012: 1 studies, 0 naming Symbol Coding in a primary outcome2013: 2 studies, 2 naming Symbol Coding in a primary outcome2014: 0 studies, 0 naming Symbol Coding in a primary outcome2015: 1 studies, 0 naming Symbol Coding in a primary outcome20152016: 2 studies, 1 naming Symbol Coding in a primary outcome2017: 1 studies, 1 naming Symbol Coding in a primary outcome2018: 3 studies, 1 naming Symbol Coding in a primary outcome2019: 5 studies, 1 naming Symbol Coding in a primary outcome2020: 0 studies, 0 naming Symbol Coding in a primary outcome20202021: 4 studies, 2 naming Symbol Coding in a primary outcome2022: 5 studies, 2 naming Symbol Coding in a primary outcome2023: 6 studies, 3 naming Symbol Coding in a primary outcome2024: 9 studies, 2 naming Symbol Coding in a primary outcome2025: 5 studies, 4 naming Symbol Coding in a primary outcome20252026: 6 studies, 4 naming Symbol Coding in a primary outcome

2026 is partly planned starts. Not shown: 1 that started before 2000.

Show as a table
Matching studies by start year
Start yearStudiesAs a primary outcome
200000
200100
200200
200300
200400
200511
200600
200700
200811
200920
201032
201110
201210
201322
201400
201510
201621
201711
201831
201951
202000
202142
202252
202363
202492
202554
202664

Library tests named most

  • Symbol Coding59 studies, 27 as a primary outcome
  • Trail Making Test26 studies, 13 as a primary outcome
  • Verbal Learning22 studies, 14 as a primary outcome
  • Digit Span Test17 studies, 11 as a primary outcome
  • Stroop Color-Word Test15 studies, 6 as a primary outcome
  • Verbal Fluency12 studies, 9 as a primary outcome
  • Category Fluency8 studies, 7 as a primary outcome
  • Short Story Recall5 studies, 2 as a primary outcome
  • Task Switching Test5 studies, 2 as a primary outcome
  • Letter-Number Sequencing Task4 studies, 3 as a primary outcome

Conditions

  • Obesity and diabetes59 studies, 27 as a primary outcome
  • Aging, frailty and exercise8 studies, 2 as a primary outcome
  • Cardiovascular disease5 studies, 2 as a primary outcome
  • Dementia and Alzheimer's4 studies, 2 as a primary outcome
  • Sleep and sleep disorders4 studies, 2 as a primary outcome
  • Mild cognitive impairment2 studies, 2 as a primary outcome
  • Schizophrenia and psychosis2 studies, 0 as a primary outcome
  • Depression and bipolar disorder2 studies, 0 as a primary outcome
  • Cancer1 study, 0 as a primary outcome

Phases

Participants

Lead sponsor: industry 4, NIH 2, other 53. Interventional 52, observational 7.

As a primary outcomeSecondary or other outcomeSymbol Coding

The studies, newest registration first

Each number opens the study's record on ClinicalTrials.gov.

Registered studies that match the filters, newest registration first, with the library tests each one names and the outcome list that names them.
StudyStartPhaseConditionsParticipantsLead sponsorStatusLibrary tests named, with the latest time point
NCT07870291Start2026PhaseNot applicableConditionsObesity and diabetesParticipants105Lead sponsorOtherStatusActive, not recruitingLibrary tests named
  • Trail Making TestPrimary12 weeks
  • Symbol CodingPrimary12 weeks
NCT07750223Start2026PhaseNot applicableConditionsObesity and diabetesParticipants105Lead sponsorOtherStatusRecruitingLibrary tests named
  • Trail Making TestPrimary10 weeks
  • Symbol CodingPrimary10 weeks
NCT07704229Start2026PhaseObservationalConditionsObesity and diabetesParticipants150Lead sponsorOtherStatusNot yet recruitingLibrary tests named
  • Trail Making TestSecondary3 years
  • Stroop Color-Word TestSecondary3 years
  • Verbal LearningSecondary3 years
  • Digit Span TestSecondary3 years
  • Symbol CodingSecondary3 years
NCT07694596Start2026PhaseNot applicableConditionsObesity and diabetesParticipants200Lead sponsorOtherStatusActive, not recruitingLibrary tests named
  • Trail Making TestPrimary12 months
  • Verbal FluencyPrimary12 months
  • Digit Span TestPrimary12 months
  • Symbol CodingPrimary12 months
  • Category FluencyPrimary12 months
NCT07485062Start2026PhasePhase 4ConditionsAging, frailty and exercise, Obesity and diabetesParticipants164Lead sponsorOtherStatusNot yet recruitingLibrary tests named
  • Trail Making TestPrimary7 months
  • Stroop Color-Word TestSecondary7 months
  • Verbal LearningSecondary7 months
  • Digit Span TestSecondary7 months
  • Symbol CodingSecondary7 months
  • Eriksen Flanker TaskSecondary7 months
NCT07420699Start2023PhaseNot applicableConditionsObesity and diabetesParticipants40Lead sponsorOtherStatusCompletedLibrary tests named
  • Verbal LearningPrimarysame day
  • Digit Span TestPrimarysame day
  • Symbol CodingPrimarysame day
  • Corsi Block-Tapping TestPrimarysame day
NCT07374705Start2026PhaseObservationalConditionsObesity and diabetesParticipants150Lead sponsorOtherStatusRecruitingLibrary tests named
  • Trail Making TestPrimary
  • Verbal LearningPrimary
  • Verbal FluencyPrimary
  • Digit Span TestPrimary
  • Symbol CodingPrimary
  • Letter-Number Sequencing TaskPrimary
NCT07284316Start2025PhasePhase 2/3ConditionsObesity and diabetesParticipants100Lead sponsorOtherStatusActive, not recruitingLibrary tests named
  • Verbal LearningPrimary12 months
  • Verbal FluencyPrimary12 months
  • Symbol CodingPrimary12 months
  • Category FluencyPrimary12 months
NCT07118904Start2025PhaseNot applicableConditionsObesity and diabetes, Sleep and sleep disordersParticipants12Lead sponsorOtherStatusCompletedLibrary tests named
  • Stroop Color-Word TestPrimary1 week
  • Symbol CodingPrimary1 week
NCT07040748Start2025PhaseNot applicableConditionsObesity and diabetesParticipants84Lead sponsorOtherStatusRecruitingLibrary tests named
  • Trail Making TestPrimary6 months
  • Stroop Color-Word TestPrimary6 months
  • Verbal LearningPrimary6 months
  • Verbal FluencyPrimary6 months
  • Digit Span TestPrimary6 months
  • Symbol CodingPrimary6 months
  • Continuous Performance TestPrimary6 months
  • Category FluencyPrimary6 months
  • Card Sorting Test (Berg)Primary6 months
  • Short Story RecallPrimary6 months
NCT06960941Start2025PhaseNot applicableConditionsObesity and diabetesParticipants24Lead sponsorOtherStatusNot yet recruitingLibrary tests named
  • Trail Making TestSecondary6 months
  • Stroop Color-Word TestSecondary6 months
  • Symbol CodingSecondary6 months
NCT06912321Start2024PhaseObservationalConditionsObesity and diabetesParticipants400Lead sponsorOtherStatusRecruitingLibrary tests named
  • Trail Making TestSecondary6 years
  • Verbal LearningPrimarysame day
  • Digit Span TestPrimarysame day
  • Symbol CodingPrimarysame day
  • Category FluencyPrimarysame day
  • Complex Figure Copy and RecallPrimarysame day
NCT06857994Start2025PhaseObservationalConditionsObesity and diabetes, Cardiovascular diseaseParticipants101Lead sponsorOtherStatusCompletedLibrary tests named
  • Trail Making TestPrimary
  • Verbal LearningPrimary
  • Verbal FluencyPrimary
  • Digit Span TestPrimary
  • Symbol CodingPrimary
  • N-Back TaskSecondary
  • Letter-Number Sequencing TaskPrimary
NCT06624462Start2023PhaseNot applicableConditionsSchizophrenia and psychosis, Depression and bipolar disorder, Obesity and diabetesParticipants84Lead sponsorOtherStatusRecruitingLibrary tests named
  • Trail Making TestOther outcome12 months
  • Symbol CodingOther outcome12 months
  • Category FluencyOther outcome12 months
NCT06524388Start2024PhaseNot applicableConditionsAging, frailty and exercise, Obesity and diabetesParticipants120Lead sponsorOtherStatusRecruitingLibrary tests named
  • Trail Making TestSecondary6 months
  • Verbal LearningSecondary6 months
  • Symbol CodingSecondary6 months
  • Picture Naming TestSecondary6 months
NCT06496412Start2024PhaseNot applicableConditionsObesity and diabetesParticipants40Lead sponsorOtherStatusRecruitingLibrary tests named
  • Trail Making TestPrimary6 months
  • Stroop Color-Word TestPrimary6 months
  • Verbal LearningPrimary6 months
  • Verbal FluencyPrimary6 months
  • Symbol CodingPrimary6 months
  • Picture Naming TestPrimary6 months
  • Task Switching TestPrimary6 months
  • Clock Drawing TaskPrimary6 months
NCT06260254Start2024PhaseNot applicableConditionsObesity and diabetes, Sleep and sleep disordersParticipants23Lead sponsorOtherStatusCompletedLibrary tests named
  • Symbol CodingSecondary
  • N-Back TaskSecondary
  • Psychomotor Vigilance TaskSecondary
  • Matrix ReasoningSecondary
  • Balloon RiskSecondary
NCT06251635Start2024PhaseNot applicableConditionsSchizophrenia and psychosis, Obesity and diabetesParticipants15Lead sponsorOtherStatusActive, not recruitingLibrary tests named
  • Symbol CodingSecondary6 months
NCT06243172Start2024PhaseObservationalConditionsObesity and diabetes, Sleep and sleep disordersParticipants60Lead sponsorOtherStatusStatus unknownLibrary tests named
  • Trail Making TestSecondarysame day
  • Verbal LearningSecondarysame day
  • Verbal FluencySecondarysame day
  • Symbol CodingSecondarysame day
  • Letter-Number Sequencing TaskSecondarysame day
NCT06242535Start2023PhaseEarly phase 1ConditionsDepression and bipolar disorder, Aging, frailty and exercise, Obesity and diabetes, Cardiovascular diseaseParticipants13Lead sponsorIndustryStatusCompletedLibrary tests named
  • Trail Making TestSecondary6 months
  • Stroop Color-Word TestSecondary6 months
  • Symbol CodingSecondary6 months
  • Eriksen Flanker TaskSecondary6 months
NCT06236256Start2024PhaseNot applicableConditionsAging, frailty and exercise, Obesity and diabetesParticipants42Lead sponsorOtherStatusCompletedLibrary tests named
  • Symbol CodingOther outcome12 months
NCT06223204Start2024PhaseNot applicableConditionsObesity and diabetesParticipants16Lead sponsorOtherStatusCompletedLibrary tests named
  • Symbol CodingSecondarysame day
NCT06122441Start2024PhaseNot applicableConditionsObesity and diabetesParticipants119Lead sponsorOtherStatusActive, not recruitingLibrary tests named
  • Symbol CodingOther outcome2 years
NCT05997316Start2023PhaseNot applicableConditionsMild cognitive impairment, Obesity and diabetesParticipants33Lead sponsorOtherStatusCompleted

Results

Library tests named
  • Trail Making TestPrimary12 weeks
  • Verbal LearningPrimary12 weeks
  • Verbal FluencyPrimary12 weeks
  • Digit Span TestPrimary12 weeks
  • Symbol CodingPrimary12 weeks
  • Category FluencyPrimary12 weeks
NCT05794009Start2022PhaseNot applicableConditionsAging, frailty and exercise, Obesity and diabetesParticipants124Lead sponsorOtherStatusCompletedLibrary tests named
  • Digit Span TestSecondarysame day
  • Symbol CodingSecondarysame day

Page 1 of 3

Questions, answered from the data

How many obesity and diabetes trials use Symbol Coding?

59 registered obesity and diabetes studies on ClinicalTrials.gov name it in an outcome measure, 27 of them in a primary outcome: 9% of the condition's 627 studies with a cognitive outcome, against 9% of all of them. It is the 6th most named test in obesity and diabetes trials.

Which tests do obesity and diabetes trials use with Symbol Coding?

The Trail Making Test (26 studies), Verbal Learning (22 studies) and the Digit Span Test (17 studies).

When do obesity and diabetes trials measure Symbol Coding?

Half of the primary outcomes that name Symbol Coding are measured within 12 weeks of the start, and the middle half from the first day to 6 months. 25 primary outcomes give a duration.

How many completed obesity and diabetes trials that use Symbol Coding have reported results?

17 of the 35 completed studies that name it, 49%, have reported results: 11 posted them on ClinicalTrials.gov, 10 have a results paper linked to the registry record, and 4 did both. The other 18 show neither. Of all completed studies with a cognitive outcome, 46% have reported results.

More on Symbol Coding and obesity and diabetes

  • Every cognitive test in obesity and diabetes trials: 627 studies
  • Symbol Coding in all clinical trials: 1,457 studies

Symbol Coding in other conditions

  • Multiple sclerosis375
  • Depression and bipolar disorder143
  • Dementia and Alzheimer's117
  • Aging, frailty and exercise116
  • Sleep and sleep disorders89
  • Mild cognitive impairment84
  • Pain and fatigue82
  • Stroke61
  • Substance use and addiction60
  • Cancer58
  • Healthy volunteers56

Other tests in obesity and diabetes trials

  • Stroop Color-Word Test103
  • Trail Making Test102
  • Verbal Learning74
  • Digit Span Test64
  • Verbal Fluency63

How the studies are counted

For each test family, the census runs ClinicalTrials.gov's own outcome search for the family's names and reads every study first posted by the day the family was counted. These studies were read on 10 November 2026. A study counts once on a page, however many tests it names. Counts for a test cover every version of the task under any of its names, so a page can count studies that used a commercial version.

The census adds two things to each record and changes nothing in it: which outcome list names the test (primary, then secondary, then other), and the condition groups, matched on the study's condition names and MeSH terms. A study can fall in several groups; one whose only condition is cognitive impairment or decline falls in “Cognitive impairment and decline”. Studies that name only instruments outside the library count in every total and share but are not listed.

A second read on 10 November 2026 added each study's overall status, whether results are posted, its intervention types, the countries of its sites and the time frame of the outcome that names each test. A time frame counts by the latest time point it names: “Baseline, 12 and 24 weeks” is 24 weeks, a single visit is within a day, and one that names no duration, such as “end of treatment”, is left out of the timings.

A third read on 10 November 2026 added the papers the registry links to each study: those its sponsor lists as reporting results, and those PubMed links to it through the study's NCT number. A study has a results paper when one of them came out in or after the month of its primary completion and PubMed does not class it as a protocol, review or comment. A paper that never gives the NCT number is not linked, so some studies counted as reporting neither did publish.

Source: ClinicalTrials.gov, a database of the U.S. National Library of Medicine, which does not endorse these pages. Every study line is in the data release 2.1.0, and the explorer's own file is clinical-trials-studies.json.

The census counts Symbol Key Game and Symbol Coding as one test family, so this page counts their studies together.

Run Symbol Coding in your trial

Choose tests with a record in registered trials, and run them in a browser at every site, on the same version each visit.

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