Clinical trials data
Digit Span Test in obesity and diabetes trials: 64 registered studies
Every registered obesity and diabetes study on ClinicalTrials.gov that names the Digit Span Test in an outcome measure: how often it is a primary outcome, the tests named with it, how large the studies are and when they measure it.
- Registered obesity and diabetes studies name it in an outcome measure
- 64
- Name it in a primary outcome, 41%
- 26 of 64
Tests named in the same studies
- 1
Verbal Learning30 studies, 15 as a primary outcome
- 2
Trail Making Test25 studies, 13 as a primary outcome
- 3
Verbal Fluency18 studies, 7 as a primary outcome
- 4
Symbol Coding17 studies, 11 as a primary outcome
- 5
Stroop Color-Word Test17 studies, 8 as a primary outcome
- 6
Category Fluency13 studies, 6 as a primary outcome
- 7
Short Story Recall9 studies, 3 as a primary outcome
- 8
Matrix Reasoning8 studies, 4 as a primary outcome
- 9
Letter-Number Sequencing Task6 studies, 5 as a primary outcome
- 10
Go/No-Go Task6 studies, 4 as a primary outcome
A test as a primary outcomeOnly in secondary or other outcomes
Studies by start year
A test as a primary outcomeOnly in secondary or other outcomes
Show as a table
| Start year | Studies | A test as a primary outcome |
|---|---|---|
| 2000 | 0 | 0 |
| 2001 | 0 | 0 |
| 2002 | 0 | 0 |
| 2003 | 0 | 0 |
| 2004 | 0 | 0 |
| 2005 | 1 | 1 |
| 2006 | 0 | 0 |
| 2007 | 0 | 0 |
| 2008 | 0 | 0 |
| 2009 | 1 | 1 |
| 2010 | 2 | 1 |
| 2011 | 0 | 0 |
| 2012 | 0 | 0 |
| 2013 | 2 | 1 |
| 2014 | 3 | 0 |
| 2015 | 4 | 1 |
| 2016 | 1 | 1 |
| 2017 | 1 | 0 |
| 2018 | 6 | 5 |
| 2019 | 4 | 1 |
| 2020 | 3 | 1 |
| 2021 | 4 | 0 |
| 2022 | 11 | 4 |
| 2023 | 4 | 2 |
| 2024 | 5 | 2 |
| 2025 | 4 | 2 |
| 2026 | 7 | 2 |
Phases and study sizes
By phase
- Phase 14 studies, 2 as a primary outcome
- Phase 23 studies, 0 as a primary outcome
- Phase 33 studies, 2 as a primary outcome
- Phase 44 studies, 1 as a primary outcome
- Not applicable38 studies, 14 as a primary outcome
- Observational12 studies, 7 as a primary outcome
Participants per study
- Not applicable53 median, 39 to 87
- Observational150 median, 92 to 517
Show as a table
| Phase | Studies with a size | Median | Middle half |
|---|---|---|---|
| Not applicable | 38 | 53 | 39 to 87 |
| Observational | 12 | 150 | 92 to 517 |
When obesity and diabetes trials measure it
Latest time point of each outcome
- Within a day16 outcomes, 8 as a primary outcome
- Up to 4 weeks6 outcomes, 3 as a primary outcome
- 1 to 3 months16 outcomes, 7 as a primary outcome
- 3 to 6 months12 outcomes, 1 as a primary outcome
- 6 to 12 months5 outcomes, 3 as a primary outcome
- 1 to 2 years1 outcomes, 0 as a primary outcome
- Over 2 years3 outcomes, 2 as a primary outcome
- No duration given5 outcomes, 2 as a primary outcome
A test as a primary outcomeOnly in secondary or other outcomes
59 of the 64 outcome measures give a duration. A single visit counts as within a day.
Status, results, interventions and countries
Status
- Recruiting11 studies, 4 as a primary outcome
- Not yet recruiting4 studies, 1 as a primary outcome
- Active, not recruiting4 studies, 2 as a primary outcome
- Completed39 studies, 17 as a primary outcome
- Stopped early2 studies, 1 as a primary outcome
- Status unknown4 studies, 1 as a primary outcome
What they test
- Behavioral16 studies, 4 as a primary outcome
- Drug11 studies, 4 as a primary outcome
- Device5 studies, 2 as a primary outcome
- Dietary supplement8 studies, 3 as a primary outcome
- Procedure2 studies, 0 as a primary outcome
- Combination product1 studies, 0 as a primary outcome
- Other23 studies, 13 as a primary outcome
- None given7 studies, 5 as a primary outcome
Intervention types as registered. A study can list several; observational studies often list none.
Where their sites are
- United States29 studies, 13 as a primary outcome
- Canada7 studies, 1 as a primary outcome
- China4 studies, 2 as a primary outcome
- Spain4 studies, 2 as a primary outcome
- United Kingdom3 studies, 0 as a primary outcome
- Denmark2 studies, 2 as a primary outcome
- Germany2 studies, 1 as a primary outcome
- Netherlands2 studies, 0 as a primary outcome
- Australia1 studies, 1 as a primary outcome
- Chile1 studies, 0 as a primary outcome
- Greece1 studies, 1 as a primary outcome
- Hong Kong1 studies, 0 as a primary outcome
20 countries in all. A study with sites in several counts in each; 3 list no site.
Reported results
Completed studies with results posted on ClinicalTrials.gov, a results paper the registry links to the study, or both.
Completed obesity and diabetes studies that name the Digit Span Test: 23 of 39, 59%
Every completed study with a cognitive outcome: 3,626 of 7,953, 46%
| Results | Completed obesity and diabetes studies that name the Digit Span Test | Every completed study |
|---|---|---|
| Results on ClinicalTrials.gov and a paper | 3, 8% | 776, 10% |
| Results on ClinicalTrials.gov only | 8, 21% | 1,139, 14% |
| A results paper only | 12, 31% | 1,711, 22% |
| Neither | 16, 41% | 4,327, 54% |
The 64 studies
64 studies match. 26 name the Digit Span Test in a primary outcome. Median size 76 participants. Median time to the primary outcome: 7 weeks.
Loading 64 studies; the filters turn on when they arrive.
2026 is partly planned starts. Not shown: 1 planned to start after 2026.
Show as a table
| Start year | Studies | As a primary outcome |
|---|---|---|
| 2000 | 0 | 0 |
| 2001 | 0 | 0 |
| 2002 | 0 | 0 |
| 2003 | 0 | 0 |
| 2004 | 0 | 0 |
| 2005 | 1 | 1 |
| 2006 | 0 | 0 |
| 2007 | 0 | 0 |
| 2008 | 0 | 0 |
| 2009 | 1 | 1 |
| 2010 | 2 | 1 |
| 2011 | 0 | 0 |
| 2012 | 0 | 0 |
| 2013 | 2 | 1 |
| 2014 | 3 | 0 |
| 2015 | 4 | 1 |
| 2016 | 1 | 1 |
| 2017 | 1 | 0 |
| 2018 | 6 | 5 |
| 2019 | 4 | 1 |
| 2020 | 3 | 1 |
| 2021 | 4 | 0 |
| 2022 | 11 | 4 |
| 2023 | 4 | 2 |
| 2024 | 5 | 2 |
| 2025 | 4 | 2 |
| 2026 | 7 | 2 |
Library tests named most
Largest condition groups
Phases
Participants
Lead sponsor: industry 2, other 62. Interventional 52, observational 12.
As a primary outcomeSecondary or other outcomeThe Digit Span Test
The studies, newest registration first
Each number opens the study's record on ClinicalTrials.gov.
| Study | Start | Phase | Conditions | Participants | Lead sponsor | Status | Library tests named, with the latest time point |
|---|---|---|---|---|---|---|---|
| NCT07862452 | Start2027 | PhaseNot applicable | ConditionsObesity and diabetes, Cardiovascular disease | Participants400 | Lead sponsorOther | StatusNot yet recruiting | Library tests named
|
| NCT07704229 | Start2026 | PhaseObservational | ConditionsObesity and diabetes | Participants150 | Lead sponsorOther | StatusNot yet recruiting | Library tests named
|
| NCT07694596 | Start2026 | PhaseNot applicable | ConditionsObesity and diabetes | Participants200 | Lead sponsorOther | StatusActive, not recruiting | Library tests named
|
| NCT07650318 | Start2026 | PhaseNot applicable | ConditionsMild cognitive impairment, Obesity and diabetes | Participants40 | Lead sponsorOther | StatusRecruiting | Library tests named
|
| NCT07642518 | Start2026 | PhaseNot applicable | ConditionsMild cognitive impairment, Obesity and diabetes | Participants38 | Lead sponsorOther | StatusNot yet recruiting | Library tests named
|
| NCT07592546 | Start2026 | PhasePhase 4 | ConditionsObesity and diabetes | Participants240 | Lead sponsorOther | StatusRecruiting | Library tests named
|
| NCT07485062 | Start2026 | PhasePhase 4 | ConditionsAging, frailty and exercise, Obesity and diabetes | Participants164 | Lead sponsorOther | StatusNot yet recruiting | Library tests named
|
| NCT07420699 | Start2023 | PhaseNot applicable | ConditionsObesity and diabetes | Participants40 | Lead sponsorOther | StatusCompleted | Library tests named
|
| NCT07374705 | Start2026 | PhaseObservational | ConditionsObesity and diabetes | Participants150 | Lead sponsorOther | StatusRecruiting | Library tests named
|
| NCT07164768 | Start2024 | PhaseObservational | ConditionsObesity and diabetes | Participants400 | Lead sponsorOther | StatusRecruiting | Library tests named
|
| NCT07040748 | Start2025 | PhaseNot applicable | ConditionsObesity and diabetes | Participants84 | Lead sponsorOther | StatusRecruiting | Library tests named
|
| NCT06931730 | Start2024 | PhaseNot applicable | ConditionsObesity and diabetes | Participants240 | Lead sponsorOther | StatusRecruiting | Library tests named
|
| NCT06912321 | Start2024 | PhaseObservational | ConditionsObesity and diabetes | Participants400 | Lead sponsorOther | StatusRecruiting | Library tests named
|
| NCT06867198 | Start2025 | PhaseNot applicable | ConditionsObesity and diabetes, Cardiovascular disease | Participants72 | Lead sponsorOther | StatusRecruiting | Library tests named
|
| NCT06857994 | Start2025 | PhaseObservational | ConditionsObesity and diabetes, Cardiovascular disease | Participants101 | Lead sponsorOther | StatusCompleted | Library tests named
|
| NCT06735651 | Start2024 | PhaseNot applicable | ConditionsObesity and diabetes | Participants30 | Lead sponsorOther | StatusRecruiting | Library tests named
|
| NCT06735599 | Start2024 | PhaseNot applicable | ConditionsObesity and diabetes, Cardiovascular disease | Participants40 | Lead sponsorOther | StatusRecruiting | Library tests named
|
| NCT06649981 | Start2025 | PhasePhase 1 | ConditionsObesity and diabetes | Participants80 | Lead sponsorOther | StatusActive, not recruiting | Library tests named
|
| NCT05997316 | Start2023 | PhaseNot applicable | ConditionsMild cognitive impairment, Obesity and diabetes | Participants33 | Lead sponsorOther | StatusCompleted | Library tests named
|
| NCT05865912 | Start2023 | PhaseNot applicable | ConditionsObesity and diabetes | Participants52 | Lead sponsorOther | StatusCompleted | Library tests named
|
| NCT05794009 | Start2022 | PhaseNot applicable | ConditionsAging, frailty and exercise, Obesity and diabetes | Participants124 | Lead sponsorOther | StatusCompleted | Library tests named
|
| NCT05709847 | Start2023 | PhaseNot applicable | ConditionsObesity and diabetes | Participants70 | Lead sponsorOther | StatusStatus unknown | Library tests named
|
| NCT05658354 | Start2022 | PhaseNot applicable | ConditionsObesity and diabetes | Participants50 | Lead sponsorOther | StatusCompleted | Library tests named
|
| NCT05651243 | Start2022 | PhaseNot applicable | ConditionsObesity and diabetes | Participants20 | Lead sponsorOther | StatusCompleted | Library tests named
|
| NCT05586386 | Start2020 | PhasePhase 1 | ConditionsObesity and diabetes | Participants60 | Lead sponsorOther | StatusCompleted | Library tests named
|
Questions, answered from the data
How many obesity and diabetes trials use the Digit Span Test?
64 registered obesity and diabetes studies on ClinicalTrials.gov name it in an outcome measure, 26 of them in a primary outcome: 10% of the condition's 627 studies with a cognitive outcome, against 10% of all of them. It is the 4th most named test in obesity and diabetes trials.
Which tests do obesity and diabetes trials use with the Digit Span Test?
Verbal Learning (30 studies), the Trail Making Test (25 studies) and Verbal Fluency (18 studies).
When do obesity and diabetes trials measure the Digit Span Test?
Half of the primary outcomes that name the Digit Span Test are measured within 7 weeks of the start, and the middle half from the first day to 4 months. 24 primary outcomes give a duration.
How many completed obesity and diabetes trials that use the Digit Span Test have reported results?
23 of the 39 completed studies that name it, 59%, have reported results: 11 posted them on ClinicalTrials.gov, 15 have a results paper linked to the registry record, and 3 did both. The other 16 show neither. Of all completed studies with a cognitive outcome, 46% have reported results.
How the studies are counted
For each test family, the census runs ClinicalTrials.gov's own outcome search for the family's names and reads every study first posted by the day the family was counted. These studies were read on 10 November 2026. A study counts once on a page, however many tests it names. Counts for a test cover every version of the task under any of its names, so a page can count studies that used a commercial version.
The census adds two things to each record and changes nothing in it: which outcome list names the test (primary, then secondary, then other), and the condition groups, matched on the study's condition names and MeSH terms. A study can fall in several groups; one whose only condition is cognitive impairment or decline falls in “Cognitive impairment and decline”. Studies that name only instruments outside the library count in every total and share but are not listed.
A second read on 10 November 2026 added each study's overall status, whether results are posted, its intervention types, the countries of its sites and the time frame of the outcome that names each test. A time frame counts by the latest time point it names: “Baseline, 12 and 24 weeks” is 24 weeks, a single visit is within a day, and one that names no duration, such as “end of treatment”, is left out of the timings.
A third read on 10 November 2026 added the papers the registry links to each study: those its sponsor lists as reporting results, and those PubMed links to it through the study's NCT number. A study has a results paper when one of them came out in or after the month of its primary completion and PubMed does not class it as a protocol, review or comment. A paper that never gives the NCT number is not linked, so some studies counted as reporting neither did publish.
Source: ClinicalTrials.gov, a database of the U.S. National Library of Medicine, which does not endorse these pages. Every study line is in the data release 2.1.0, and the explorer's own file is clinical-trials-studies.json.
Run the Digit Span Test in your trial
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