Clinical trials data
Digit Span Test in Parkinson's disease trials: 86 registered studies
Every registered Parkinson's disease study on ClinicalTrials.gov that names the Digit Span Test in an outcome measure: how often it is a primary outcome, the tests named with it, how large the studies are and when they measure it.
- Registered Parkinson's disease studies name it in an outcome measure
- 86
- Name it in a primary outcome, 17%
- 15 of 86
Tests named in the same studies
- 1
Verbal Fluency43 studies, 8 as a primary outcome
- 2
Trail Making Test42 studies, 8 as a primary outcome
- 3
Stroop Color-Word Test37 studies, 8 as a primary outcome
- 4
Verbal Learning21 studies, 5 as a primary outcome
- 5
Category Fluency18 studies, 3 as a primary outcome
- 6
Picture Naming Test14 studies, 3 as a primary outcome
- 7
Line Angle Matching10 studies, 3 as a primary outcome
- 8
Symbol Coding10 studies, 2 as a primary outcome
- 9
Short Story Recall8 studies, 3 as a primary outcome
- 10
Card Sorting Test (Berg)8 studies, 2 as a primary outcome
A test as a primary outcomeOnly in secondary or other outcomes
Studies by start year
A test as a primary outcomeOnly in secondary or other outcomes
Show as a table
| Start year | Studies | A test as a primary outcome |
|---|---|---|
| 2000 | 0 | 0 |
| 2001 | 0 | 0 |
| 2002 | 0 | 0 |
| 2003 | 0 | 0 |
| 2004 | 0 | 0 |
| 2005 | 0 | 0 |
| 2006 | 0 | 0 |
| 2007 | 1 | 0 |
| 2008 | 0 | 0 |
| 2009 | 1 | 0 |
| 2010 | 1 | 0 |
| 2011 | 2 | 1 |
| 2012 | 3 | 1 |
| 2013 | 2 | 1 |
| 2014 | 3 | 0 |
| 2015 | 3 | 0 |
| 2016 | 2 | 0 |
| 2017 | 6 | 0 |
| 2018 | 7 | 1 |
| 2019 | 7 | 1 |
| 2020 | 7 | 2 |
| 2021 | 5 | 1 |
| 2022 | 6 | 1 |
| 2023 | 6 | 1 |
| 2024 | 6 | 3 |
| 2025 | 4 | 1 |
| 2026 | 14 | 1 |
Phases and study sizes
By phase
- Early phase 12 studies, 0 as a primary outcome
- Phase 12 studies, 0 as a primary outcome
- Phase 1/23 studies, 1 as a primary outcome
- Phase 26 studies, 0 as a primary outcome
- Phase 31 studies, 1 as a primary outcome
- Phase 42 studies, 0 as a primary outcome
- Not applicable61 studies, 9 as a primary outcome
- Observational9 studies, 4 as a primary outcome
Participants per study
- Not applicable40 median, 25 to 66
Show as a table
| Phase | Studies with a size | Median | Middle half |
|---|---|---|---|
| Not applicable | 61 | 40 | 25 to 66 |
When Parkinson's disease trials measure it
Latest time point of each outcome
- Within a day13 outcomes, 4 as a primary outcome
- Up to 4 weeks20 outcomes, 4 as a primary outcome
- 1 to 3 months27 outcomes, 3 as a primary outcome
- 3 to 6 months15 outcomes, 3 as a primary outcome
- 6 to 12 months2 outcomes, 0 as a primary outcome
- 1 to 2 years3 outcomes, 0 as a primary outcome
- Over 2 years2 outcomes, 1 as a primary outcome
- No duration given4 outcomes, 0 as a primary outcome
A test as a primary outcomeOnly in secondary or other outcomes
82 of the 86 outcome measures give a duration. A single visit counts as within a day.
Status, results, interventions and countries
Status
- Recruiting19 studies, 5 as a primary outcome
- Not yet recruiting4 studies, 1 as a primary outcome
- Active, not recruiting3 studies, 0 as a primary outcome
- Completed35 studies, 7 as a primary outcome
- Stopped early4 studies, 0 as a primary outcome
- Status unknown21 studies, 2 as a primary outcome
What they test
- Behavioral24 studies, 4 as a primary outcome
- Drug10 studies, 0 as a primary outcome
- Device27 studies, 3 as a primary outcome
- Procedure4 studies, 2 as a primary outcome
- Diagnostic test3 studies, 0 as a primary outcome
- Biological1 studies, 0 as a primary outcome
- Radiation1 studies, 1 as a primary outcome
- Genetic1 studies, 1 as a primary outcome
- Other24 studies, 6 as a primary outcome
- None given4 studies, 1 as a primary outcome
Intervention types as registered. A study can list several; observational studies often list none.
Where their sites are
- United States22 studies, 2 as a primary outcome
- Taiwan9 studies, 4 as a primary outcome
- Türkiye6 studies, 3 as a primary outcome
- China5 studies, 1 as a primary outcome
- France5 studies, 0 as a primary outcome
- Netherlands5 studies, 0 as a primary outcome
- South Korea5 studies, 0 as a primary outcome
- Brazil4 studies, 0 as a primary outcome
- Switzerland4 studies, 1 as a primary outcome
- Canada3 studies, 1 as a primary outcome
- Sweden3 studies, 0 as a primary outcome
- United Kingdom3 studies, 1 as a primary outcome
23 countries in all. A study with sites in several counts in each; 4 list no site.
Reported results
Completed studies with results posted on ClinicalTrials.gov, a results paper the registry links to the study, or both.
Completed Parkinson's disease studies that name the Digit Span Test: 21 of 35, 60%
Every completed study with a cognitive outcome: 3,626 of 7,953, 46%
| Results | Completed Parkinson's disease studies that name the Digit Span Test | Every completed study |
|---|---|---|
| Results on ClinicalTrials.gov and a paper | 6, 17% | 776, 10% |
| Results on ClinicalTrials.gov only | 6, 17% | 1,139, 14% |
| A results paper only | 9, 26% | 1,711, 22% |
| Neither | 14, 40% | 4,327, 54% |
The 86 studies
86 studies match. 15 name the Digit Span Test in a primary outcome. Median size 40 participants. Median time to the primary outcome: 4 weeks.
Loading 86 studies; the filters turn on when they arrive.
2026 is partly planned starts.
Show as a table
| Start year | Studies | As a primary outcome |
|---|---|---|
| 2000 | 0 | 0 |
| 2001 | 0 | 0 |
| 2002 | 0 | 0 |
| 2003 | 0 | 0 |
| 2004 | 0 | 0 |
| 2005 | 0 | 0 |
| 2006 | 0 | 0 |
| 2007 | 1 | 0 |
| 2008 | 0 | 0 |
| 2009 | 1 | 0 |
| 2010 | 1 | 0 |
| 2011 | 2 | 1 |
| 2012 | 3 | 1 |
| 2013 | 2 | 1 |
| 2014 | 3 | 0 |
| 2015 | 3 | 0 |
| 2016 | 2 | 0 |
| 2017 | 6 | 0 |
| 2018 | 7 | 1 |
| 2019 | 7 | 1 |
| 2020 | 7 | 2 |
| 2021 | 5 | 1 |
| 2022 | 6 | 1 |
| 2023 | 6 | 1 |
| 2024 | 6 | 3 |
| 2025 | 4 | 1 |
| 2026 | 14 | 1 |
Library tests named most
Conditions
Phases
Participants
Lead sponsor: industry 2, other 84. Interventional 77, observational 9.
As a primary outcomeSecondary or other outcomeThe Digit Span Test
The studies, newest registration first
Each number opens the study's record on ClinicalTrials.gov.
| Study | Start | Phase | Conditions | Participants | Lead sponsor | Status | Library tests named, with the latest time point |
|---|---|---|---|---|---|---|---|
| NCT07838675 | Start2026 | PhaseNot applicable | ConditionsParkinson's disease | Participants120 | Lead sponsorOther | StatusRecruiting | Library tests named
|
| NCT07832695 | Start2026 | PhaseNot applicable | ConditionsParkinson's disease | Participants90 | Lead sponsorOther | StatusRecruiting | Library tests named
|
| NCT07813156 | Start2026 | PhaseNot applicable | ConditionsParkinson's disease | Participants24 | Lead sponsorOther | StatusNot yet recruiting | Library tests named
|
| NCT07678983 | Start2026 | PhaseNot applicable | ConditionsParkinson's disease | Participants66 | Lead sponsorOther | StatusActive, not recruiting | Library tests named
|
| NCT07636538 | Start2026 | PhaseNot applicable | ConditionsMild cognitive impairment, Stroke, Parkinson's disease | Participants30 | Lead sponsorOther | StatusNot yet recruiting | Library tests named
|
| NCT07610369 | Start2026 | PhasePhase 2 | ConditionsParkinson's disease, Depression and bipolar disorder | Participants40 | Lead sponsorOther | StatusRecruiting | Library tests named
|
| NCT07582497 | Start2026 | PhaseNot applicable | ConditionsStroke, Parkinson's disease | Participants60 | Lead sponsorOther | StatusNot yet recruiting | Library tests named
|
| NCT07569120 | Start2026 | PhaseNot applicable | ConditionsParkinson's disease, Healthy volunteers, Aging, frailty and exercise | Participants165 | Lead sponsorOther | StatusRecruiting | Library tests named
|
| NCT07540325 | Start2026 | PhaseObservational | ConditionsParkinson's disease | Participants30 | Lead sponsorOther | StatusNot yet recruiting | Library tests named
|
| NCT07536022 | Start2026 | PhaseNot applicable | ConditionsParkinson's disease | Participants16 | Lead sponsorOther | StatusRecruiting | Library tests named
|
| NCT07518290 | Start2026 | PhaseNot applicable | ConditionsParkinson's disease | Participants98 | Lead sponsorOther | StatusRecruiting | Library tests named
|
| NCT07455760 | Start2026 | PhaseNot applicable | ConditionsParkinson's disease | Participants80 | Lead sponsorOther | StatusRecruiting | Library tests named
|
| NCT07355842 | Start2026 | PhaseNot applicable | ConditionsParkinson's disease, Sleep and sleep disorders | Participants80 | Lead sponsorOther | StatusRecruiting | Library tests named
|
| NCT07277205 | Start2026 | PhaseNot applicable | ConditionsParkinson's disease | Participants45 | Lead sponsorOther | StatusRecruiting | Library tests named
|
| NCT07271927 | Start2025 | PhaseNot applicable | ConditionsParkinson's disease | Participants15 | Lead sponsorOther | StatusRecruiting | Library tests named
|
| NCT07240272 | Start2023 | PhaseNot applicable | ConditionsParkinson's disease | Participants28 | Lead sponsorOther | StatusCompleted | Library tests named
|
| NCT07058714 | Start2025 | PhaseObservational | ConditionsParkinson's disease | Participants30 | Lead sponsorOther | StatusCompleted | Library tests named
|
| NCT06782724 | Start2025 | PhasePhase 2 | ConditionsParkinson's disease, Multiple sclerosis, Depression and bipolar disorder, Lung disease | Participants108 | Lead sponsorOther | StatusRecruiting | Library tests named
|
| NCT06588920 | Start2024 | PhaseObservational | ConditionsParkinson's disease, Healthy volunteers, Aging, frailty and exercise | Participants70 | Lead sponsorOther | StatusRecruiting | Library tests named
|
| NCT06588439 | Start2025 | PhaseNot applicable | ConditionsParkinson's disease | Participants50 | Lead sponsorOther | StatusRecruiting | Library tests named
|
| NCT06467695 | Start2024 | PhaseNot applicable | ConditionsParkinson's disease, Depression and bipolar disorder | Participants40 | Lead sponsorOther | StatusRecruiting | Library tests named
|
| NCT06416722 | Start2024 | PhaseNot applicable | ConditionsParkinson's disease | Participants30 | Lead sponsorOther | StatusRecruiting | Library tests named
|
| NCT06399731 | Start2024 | PhaseNot applicable | ConditionsMild cognitive impairment, Parkinson's disease | Participants20 | Lead sponsorOther | StatusRecruiting | Library tests named
|
| NCT06350617 | Start2024 | PhaseNot applicable | ConditionsParkinson's disease | Participants60 | Lead sponsorOther | StatusRecruiting | Library tests named
|
| NCT06080659 | Start2023 | PhaseNot applicable | ConditionsDementia and Alzheimer's, Parkinson's disease | Participants120 | Lead sponsorOther | StatusRecruiting | Library tests named
|
Questions, answered from the data
How many Parkinson's disease trials use the Digit Span Test?
86 registered Parkinson's disease studies on ClinicalTrials.gov name it in an outcome measure, 15 of them in a primary outcome: 10% of the condition's 892 studies with a cognitive outcome, against 10% of all of them. It is the 4th most named test in Parkinson's disease trials.
Which tests do Parkinson's disease trials use with the Digit Span Test?
Verbal Fluency (43 studies), the Trail Making Test (42 studies) and the Stroop Color-Word Test (37 studies).
When do Parkinson's disease trials measure the Digit Span Test?
Half of the primary outcomes that name the Digit Span Test are measured within 4 weeks of the start, and the middle half from 2 days to 4 months. 15 primary outcomes give a duration.
How many completed Parkinson's disease trials that use the Digit Span Test have reported results?
21 of the 35 completed studies that name it, 60%, have reported results: 12 posted them on ClinicalTrials.gov, 15 have a results paper linked to the registry record, and 6 did both. The other 14 show neither. Of all completed studies with a cognitive outcome, 46% have reported results.
How the studies are counted
For each test family, the census runs ClinicalTrials.gov's own outcome search for the family's names and reads every study first posted by the day the family was counted. These studies were read on 10 November 2026. A study counts once on a page, however many tests it names. Counts for a test cover every version of the task under any of its names, so a page can count studies that used a commercial version.
The census adds two things to each record and changes nothing in it: which outcome list names the test (primary, then secondary, then other), and the condition groups, matched on the study's condition names and MeSH terms. A study can fall in several groups; one whose only condition is cognitive impairment or decline falls in “Cognitive impairment and decline”. Studies that name only instruments outside the library count in every total and share but are not listed.
A second read on 10 November 2026 added each study's overall status, whether results are posted, its intervention types, the countries of its sites and the time frame of the outcome that names each test. A time frame counts by the latest time point it names: “Baseline, 12 and 24 weeks” is 24 weeks, a single visit is within a day, and one that names no duration, such as “end of treatment”, is left out of the timings.
A third read on 10 November 2026 added the papers the registry links to each study: those its sponsor lists as reporting results, and those PubMed links to it through the study's NCT number. A study has a results paper when one of them came out in or after the month of its primary completion and PubMed does not class it as a protocol, review or comment. A paper that never gives the NCT number is not linked, so some studies counted as reporting neither did publish.
Source: ClinicalTrials.gov, a database of the U.S. National Library of Medicine, which does not endorse these pages. Every study line is in the data release 2.1.0, and the explorer's own file is clinical-trials-studies.json.
Run the Digit Span Test in your trial
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