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    16,361Registered studies name a cognitive test in an outcome measure11,688 name a test you can run hereExplore the studies
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  5. /Stroke
  6. /Digit Span Test

Clinical trials data

Digit Span Test in stroke trials: 100 registered studies

Every registered stroke study on ClinicalTrials.gov that names the Digit Span Test in an outcome measure: how often it is a primary outcome, the tests named with it, how large the studies are and when they measure it.

Registered stroke studies name it in an outcome measure
100
Name it in a primary outcome, 30%
30 of 100
Of the condition's 1,233 studies name it, against 10% of all registered studies
8%
Other conditions
Median participants per study
45
By phase
Try the Digit Span Test

Tests named in the same studies

The library tests that stroke studies naming the Digit Span Test name most often beside it.
  1. 1

    Trail Making Test56 studies, 17 as a primary outcome

  2. 2

    Stroop Color-Word Test36 studies, 10 as a primary outcome

  3. 3

    Verbal Fluency31 studies, 10 as a primary outcome

  4. 4

    Verbal Learning28 studies, 6 as a primary outcome

  5. 5

    Symbol Coding16 studies, 3 as a primary outcome

  6. 6

    Category Fluency15 studies, 5 as a primary outcome

  7. 7

    Picture Naming Test11 studies, 6 as a primary outcome

  8. 8

    Complex Figure Copy and Recall9 studies, 3 as a primary outcome

  9. 9

    Corsi Block-Tapping Test9 studies, 3 as a primary outcome

  10. 10

    Cancellation Test9 studies, 2 as a primary outcome

A test as a primary outcomeOnly in secondary or other outcomes

Studies by start year

Each study counted once. 2026 is partly planned starts.
02000: 0 studies, 0 with a test as a primary outcome20002001: 0 studies, 0 with a test as a primary outcome2002: 0 studies, 0 with a test as a primary outcome2003: 0 studies, 0 with a test as a primary outcome2004: 0 studies, 0 with a test as a primary outcome2005: 0 studies, 0 with a test as a primary outcome20052006: 0 studies, 0 with a test as a primary outcome2007: 0 studies, 0 with a test as a primary outcome2008: 0 studies, 0 with a test as a primary outcome2009: 1 studies, 0 with a test as a primary outcome2010: 1 studies, 1 with a test as a primary outcome20102011: 0 studies, 0 with a test as a primary outcome2012: 1 studies, 0 with a test as a primary outcome2013: 3 studies, 1 with a test as a primary outcome2014: 3 studies, 2 with a test as a primary outcome2015: 4 studies, 2 with a test as a primary outcome20152016: 5 studies, 1 with a test as a primary outcome2017: 6 studies, 2 with a test as a primary outcome2018: 8 studies, 0 with a test as a primary outcome2019: 5 studies, 0 with a test as a primary outcome2020: 7 studies, 3 with a test as a primary outcome20202021: 5 studies, 3 with a test as a primary outcome2022: 7 studies, 1 with a test as a primary outcome2023: 9 studies, 1 with a test as a primary outcome2024: 9 studies, 3 with a test as a primary outcome2025: 13 studies, 5 with a test as a primary outcome20252026: 13 studies, 5 with a test as a primary outcome

A test as a primary outcomeOnly in secondary or other outcomes

Show as a table
Registered studies by start year
Start yearStudiesA test as a primary outcome
200000
200100
200200
200300
200400
200500
200600
200700
200800
200910
201011
201100
201210
201331
201432
201542
201651
201762
201880
201950
202073
202153
202271
202391
202493
2025135
2026135

Phases and study sizes

By phase

  • Phase 24 studies, 2 as a primary outcome
  • Phase 2/32 studies, 0 as a primary outcome
  • Phase 32 studies, 1 as a primary outcome
  • Phase 41 studies, 0 as a primary outcome
  • Not applicable77 studies, 25 as a primary outcome
  • Observational14 studies, 2 as a primary outcome

Participants per study

102050100200
  • Not applicable41 median, 20 to 84
  • Observational131 median, 70 to 238
Participants per study. The bar spans the middle half of the studies in each phase, the mark is the median, and the axis is logarithmic. Phases with fewer than 10 studies that give a size are left out.
Show as a table
Participants per stroke study that names the Digit Span Test, by phase
PhaseStudies with a sizeMedianMiddle half
Not applicable754120 to 84
Observational1413170 to 238

When stroke trials measure it

Half of the primary outcomes that name the Digit Span Test are measured within 8 weeks of the start, and the middle half from 1 week to 13 weeks. 29 primary outcomes give a duration.

Latest time point of each outcome

  • Within a day15 outcomes, 7 as a primary outcome
  • Up to 4 weeks22 outcomes, 6 as a primary outcome
  • 1 to 3 months37 outcomes, 11 as a primary outcome
  • 3 to 6 months11 outcomes, 4 as a primary outcome
  • 6 to 12 months5 outcomes, 0 as a primary outcome
  • 1 to 2 years2 outcomes, 0 as a primary outcome
  • Over 2 years4 outcomes, 1 as a primary outcome
  • No duration given4 outcomes, 1 as a primary outcome

A test as a primary outcomeOnly in secondary or other outcomes

96 of the 100 outcome measures give a duration. A single visit counts as within a day.

Status, results, interventions and countries

Status

  • Recruiting17 studies, 5 as a primary outcome
  • Not yet recruiting10 studies, 4 as a primary outcome
  • Active, not recruiting4 studies, 1 as a primary outcome
  • Completed42 studies, 17 as a primary outcome
  • Stopped early6 studies, 0 as a primary outcome
  • Status unknown21 studies, 3 as a primary outcome

What they test

  • Behavioral37 studies, 9 as a primary outcome
  • Drug5 studies, 2 as a primary outcome
  • Device30 studies, 6 as a primary outcome
  • Dietary supplement1 studies, 1 as a primary outcome
  • Procedure2 studies, 0 as a primary outcome
  • Diagnostic test3 studies, 0 as a primary outcome
  • Genetic1 studies, 0 as a primary outcome
  • Other33 studies, 15 as a primary outcome
  • None given5 studies, 1 as a primary outcome

Intervention types as registered. A study can list several; observational studies often list none.

Where their sites are

  • United States18 studies, 5 as a primary outcome
  • Italy7 studies, 2 as a primary outcome
  • Spain7 studies, 4 as a primary outcome
  • Canada6 studies, 0 as a primary outcome
  • Netherlands6 studies, 1 as a primary outcome
  • South Korea6 studies, 0 as a primary outcome
  • Türkiye6 studies, 4 as a primary outcome
  • Norway5 studies, 0 as a primary outcome
  • Taiwan5 studies, 4 as a primary outcome
  • Switzerland4 studies, 0 as a primary outcome
  • China3 studies, 0 as a primary outcome
  • Singapore3 studies, 0 as a primary outcome

27 countries in all. A study with sites in several counts in each; 10 list no site.

Reported results

Completed studies with results posted on ClinicalTrials.gov, a results paper the registry links to the study, or both.

Completed stroke studies that name the Digit Span Test: 16 of 42, 38%

Every completed study with a cognitive outcome: 3,626 of 7,953, 46%

Completed stroke studies that name the Digit Span Test and every completed study, by how they reported results
ResultsCompleted stroke studies that name the Digit Span TestEvery completed study
Results on ClinicalTrials.gov and a paper0, 0%776, 10%
Results on ClinicalTrials.gov only2, 5%1,139, 14%
A results paper only14, 33%1,711, 22%
Neither26, 62%4,327, 54%

The 100 studies

Filter by phase, sponsor, status, country, intervention, outcome list, size and start year. Each study links to its record on ClinicalTrials.gov.
ConditionStroke
TestThe Digit Span Test

100 studies match. 30 name the Digit Span Test in a primary outcome. Median size 45 participants. Median time to the primary outcome: 8 weeks.

Loading 100 studies; the filters turn on when they arrive.

By start year
0510152000: 0 studies, 0 naming the Digit Span Test in a primary outcome20002001: 0 studies, 0 naming the Digit Span Test in a primary outcome2002: 0 studies, 0 naming the Digit Span Test in a primary outcome2003: 0 studies, 0 naming the Digit Span Test in a primary outcome2004: 0 studies, 0 naming the Digit Span Test in a primary outcome2005: 0 studies, 0 naming the Digit Span Test in a primary outcome20052006: 0 studies, 0 naming the Digit Span Test in a primary outcome2007: 0 studies, 0 naming the Digit Span Test in a primary outcome2008: 0 studies, 0 naming the Digit Span Test in a primary outcome2009: 1 studies, 0 naming the Digit Span Test in a primary outcome2010: 1 studies, 1 naming the Digit Span Test in a primary outcome20102011: 0 studies, 0 naming the Digit Span Test in a primary outcome2012: 1 studies, 0 naming the Digit Span Test in a primary outcome2013: 3 studies, 1 naming the Digit Span Test in a primary outcome2014: 3 studies, 2 naming the Digit Span Test in a primary outcome2015: 4 studies, 2 naming the Digit Span Test in a primary outcome20152016: 5 studies, 1 naming the Digit Span Test in a primary outcome2017: 6 studies, 2 naming the Digit Span Test in a primary outcome2018: 8 studies, 0 naming the Digit Span Test in a primary outcome2019: 5 studies, 0 naming the Digit Span Test in a primary outcome2020: 7 studies, 3 naming the Digit Span Test in a primary outcome20202021: 5 studies, 3 naming the Digit Span Test in a primary outcome2022: 7 studies, 1 naming the Digit Span Test in a primary outcome2023: 9 studies, 1 naming the Digit Span Test in a primary outcome2024: 9 studies, 3 naming the Digit Span Test in a primary outcome2025: 13 studies, 5 naming the Digit Span Test in a primary outcome20252026: 13 studies, 5 naming the Digit Span Test in a primary outcome

2026 is partly planned starts.

Show as a table
Matching studies by start year
Start yearStudiesAs a primary outcome
200000
200100
200200
200300
200400
200500
200600
200700
200800
200910
201011
201100
201210
201331
201432
201542
201651
201762
201880
201950
202073
202153
202271
202391
202493
2025135
2026135

Library tests named most

  • Digit Span Test100 studies, 30 as a primary outcome
  • Trail Making Test56 studies, 17 as a primary outcome
  • Stroop Color-Word Test36 studies, 10 as a primary outcome
  • Verbal Fluency31 studies, 10 as a primary outcome
  • Verbal Learning28 studies, 6 as a primary outcome
  • Symbol Coding16 studies, 3 as a primary outcome
  • Category Fluency15 studies, 5 as a primary outcome
  • Picture Naming Test11 studies, 6 as a primary outcome
  • Complex Figure Copy and Recall9 studies, 3 as a primary outcome
  • Corsi Block-Tapping Test9 studies, 3 as a primary outcome

Largest condition groups

  • Stroke100 studies, 30 as a primary outcome
  • Brain injury and concussion15 studies, 6 as a primary outcome
  • Parkinson's disease4 studies, 0 as a primary outcome
  • Depression and bipolar disorder3 studies, 1 as a primary outcome
  • Aging, frailty and exercise3 studies, 1 as a primary outcome
  • Pain and fatigue3 studies, 1 as a primary outcome
  • Dementia and Alzheimer's2 studies, 1 as a primary outcome
  • ADHD2 studies, 1 as a primary outcome
  • Cardiovascular disease2 studies, 0 as a primary outcome
  • Mild cognitive impairment1 study, 0 as a primary outcome
  • Multiple sclerosis1 study, 0 as a primary outcome
  • Cancer1 study, 0 as a primary outcome

Phases

Participants

Lead sponsor: industry 4, other 96. Interventional 86, observational 14.

As a primary outcomeSecondary or other outcomeThe Digit Span Test

The studies, newest registration first

Each number opens the study's record on ClinicalTrials.gov.

Registered studies that match the filters, newest registration first, with the library tests each one names and the outcome list that names them.
StudyStartPhaseConditionsParticipantsLead sponsorStatusLibrary tests named, with the latest time point
NCT07887776Start2025PhaseObservationalConditionsStrokeParticipants66Lead sponsorOtherStatusCompletedLibrary tests named
  • Stroop Color-Word TestSecondary
  • Digit Span TestSecondary
NCT07817316Start2026PhaseNot applicableConditionsStroke, Brain injury and concussionParticipants30Lead sponsorOtherStatusRecruitingLibrary tests named
  • Digit Span TestPrimary3 weeks
  • Continuous Performance TestPrimary3 weeks
  • Oddball Target DetectionPrimary3 weeks
NCT07807176Start2026PhaseNot applicableConditionsStrokeParticipants150Lead sponsorOtherStatusNot yet recruitingLibrary tests named
  • Trail Making TestPrimary13 weeks
  • Digit Span TestPrimary13 weeks
  • Symbol CodingSecondary13 weeks
  • Paired Associate LearningSecondary13 weeks
  • Rapid Visual Information ProcessingPrimary13 weeks
  • Intra/Extra Dimensional Set ShiftPrimary13 weeks
NCT07792811Start2026PhasePhase 2/3ConditionsStrokeParticipants84Lead sponsorOtherStatusNot yet recruitingLibrary tests named
  • Verbal FluencySecondary14 weeks
  • Digit Span TestSecondary14 weeks
  • Line Bisection TestSecondary14 weeks
  • Design Fluency TestSecondary14 weeks
  • Token Commands TaskSecondary14 weeks
NCT07719387Start2025PhaseNot applicableConditionsStrokeParticipants20Lead sponsorOtherStatusRecruitingLibrary tests named
  • Verbal LearningSecondary6 weeks
  • Digit Span TestSecondary6 weeks
  • Short Story RecallSecondary6 weeks
NCT07636538Start2026PhaseNot applicableConditionsMild cognitive impairment, Stroke, Parkinson's diseaseParticipants30Lead sponsorOtherStatusNot yet recruitingLibrary tests named
  • Trail Making TestSecondary
  • Stroop Color-Word TestSecondary
  • Digit Span TestSecondary
NCT07608588Start2026PhaseNot applicableConditionsStrokeParticipants45Lead sponsorOtherStatusRecruitingLibrary tests named
  • Trail Making TestSecondary4 weeks
  • Digit Span TestSecondary4 weeks
  • Picture Naming TestPrimary4 weeks
  • Eriksen Flanker TaskSecondary4 weeks
NCT07588997Start2025PhaseNot applicableConditionsStrokeParticipants18Lead sponsorOtherStatusRecruitingLibrary tests named
  • Trail Making TestPrimary13 weeks
  • Stroop Color-Word TestPrimary13 weeks
  • Verbal FluencyPrimary13 weeks
  • Digit Span TestPrimary13 weeks
NCT07586566Start2026PhaseNot applicableConditionsStroke, Brain injury and concussionParticipants15Lead sponsorOtherStatusNot yet recruitingLibrary tests named
  • Digit Span TestPrimary3 weeks
  • Continuous Performance TestPrimary3 weeks
  • Cancellation TestPrimary3 weeks
NCT07582497Start2026PhaseNot applicableConditionsStroke, Parkinson's diseaseParticipants60Lead sponsorOtherStatusNot yet recruitingLibrary tests named
  • Trail Making TestSecondary13 weeks
  • Digit Span TestSecondary13 weeks
  • Corsi Block-Tapping TestSecondary13 weeks
NCT07541560Start2025PhaseNot applicableConditionsStrokeParticipants90Lead sponsorOtherStatusRecruitingLibrary tests named
  • Trail Making TestSecondary7 weeks
  • Verbal LearningSecondary7 weeks
  • Digit Span TestSecondary7 weeks
NCT07522463Start2026PhaseNot applicableConditionsStrokeParticipants44Lead sponsorOtherStatusNot yet recruitingLibrary tests named
  • Trail Making TestPrimary4 months
  • Stroop Color-Word TestPrimary4 months
  • Digit Span TestPrimary4 months
NCT07446062Start2026PhaseNot applicableConditionsStroke, Aging, frailty and exerciseParticipants52Lead sponsorOtherStatusNot yet recruitingLibrary tests named
  • Trail Making TestPrimary13 weeks
  • Digit Span TestSecondary13 weeks
NCT07445841Start2026PhaseNot applicableConditionsStrokeParticipants120Lead sponsorOtherStatusRecruitingLibrary tests named
  • Trail Making TestSecondary12 months
  • Digit Span TestSecondary12 months
  • Symbol CodingSecondary12 months
  • Category FluencySecondary12 months
NCT07429526Start2013PhaseNot applicableConditionsStroke, Brain injury and concussion, Pain and fatigueParticipants12Lead sponsorOtherStatusCompleted

Paper

Library tests named
  • Verbal LearningPrimary13 weeks
  • Digit Span TestPrimary13 weeks
  • Paced Visual Serial Addition TestPrimary13 weeks
NCT07427511Start2026PhaseNot applicableConditionsStrokeParticipants120Lead sponsorOtherStatusRecruitingLibrary tests named
  • Trail Making TestOther outcome15 months
  • Stroop Color-Word TestOther outcome15 months
  • Verbal FluencyOther outcome15 months
  • Digit Span TestOther outcome15 months
  • Go/No-Go TaskOther outcome15 months
  • Category FluencyOther outcome15 months
  • Corsi Block-Tapping TestOther outcome15 months
  • Design Fluency TestOther outcome15 months
NCT07345481Start2026PhaseObservationalConditionsStroke, Brain injury and concussionParticipants40Lead sponsorOtherStatusRecruitingLibrary tests named
  • Trail Making TestSecondarysame day
  • Stroop Color-Word TestSecondarysame day
  • Verbal LearningSecondarysame day
  • Digit Span TestSecondarysame day
  • Task Switching TestSecondarysame day
  • Serial Reaction TimeSecondarysame day
NCT07322614Start2021PhaseNot applicableConditionsStrokeParticipants60Lead sponsorOtherStatusCompleted

Paper

Library tests named
  • Stroop Color-Word TestPrimary6 months
  • Digit Span TestPrimary6 months
  • Category FluencyPrimary6 months
  • Cancellation TestPrimary6 months
  • Corsi Block-Tapping TestPrimary6 months
  • Line Bisection TestPrimary6 months
NCT07281313Start2025PhaseNot applicableConditionsStrokeParticipants120Lead sponsorOtherStatusRecruitingLibrary tests named
  • Trail Making TestSecondary1 week
  • Stroop Color-Word TestSecondary1 week
  • Verbal FluencySecondary1 week
  • Digit Span TestSecondary1 week
  • Picture Naming TestSecondary1 week
  • Simple Reaction TimeSecondary1 week
  • Design Fluency TestSecondary1 week
NCT07200661Start2024PhaseNot applicableConditionsStroke, Cardiovascular diseaseParticipants30Lead sponsorOtherStatusCompletedLibrary tests named
  • Stroop Color-Word TestSecondary4 weeks
  • Digit Span TestSecondary4 weeks
NCT07144930Start2025PhaseNot applicableConditionsStroke, Healthy volunteersParticipants210Lead sponsorOtherStatusRecruitingLibrary tests named
  • Trail Making TestPrimary4 months
  • Stroop Color-Word TestPrimary4 months
  • Digit Span TestPrimary4 months
  • Task Switching TestPrimary4 months
NCT07119827Start2025PhaseObservationalConditionsStroke, Brain injury and concussionParticipants250Lead sponsorOtherStatusRecruitingLibrary tests named
  • Stroop Color-Word TestSecondary13 weeks
  • Verbal LearningSecondary13 weeks
  • Verbal FluencySecondary18 months
  • Digit Span TestSecondary13 weeks
  • Category FluencySecondary18 months
  • Complex Figure Copy and RecallSecondary13 weeks
  • Corsi Block-Tapping TestSecondary13 weeks
  • Design Fluency TestSecondary13 weeks
NCT07010536Start2025PhaseNot applicableConditionsStrokeParticipants30Lead sponsorOtherStatusCompletedLibrary tests named
  • Digit Span TestPrimary6 weeks
  • Card Sorting Test (Berg)Primary6 weeks
  • Cancellation TestSecondary6 weeks
NCT06968923Start2018PhaseNot applicableConditionsStrokeParticipants90Lead sponsorOtherStatusRecruitingLibrary tests named
  • Trail Making TestSecondary6 months
  • Digit Span TestSecondary6 months
  • Symbol CodingSecondary6 months
NCT06938477Start2024PhaseNot applicableConditionsStrokeParticipants20Lead sponsorOtherStatusCompletedLibrary tests named
  • Digit Span TestPrimary8 weeks

Page 1 of 4

Questions, answered from the data

How many stroke trials use the Digit Span Test?

100 registered stroke studies on ClinicalTrials.gov name it in an outcome measure, 30 of them in a primary outcome: 8% of the condition's 1,233 studies with a cognitive outcome, against 10% of all of them. It is the 4th most named test in stroke trials.

Which tests do stroke trials use with the Digit Span Test?

The Trail Making Test (56 studies), the Stroop Color-Word Test (36 studies) and Verbal Fluency (31 studies).

When do stroke trials measure the Digit Span Test?

Half of the primary outcomes that name the Digit Span Test are measured within 8 weeks of the start, and the middle half from 1 week to 13 weeks. 29 primary outcomes give a duration.

How many completed stroke trials that use the Digit Span Test have reported results?

16 of the 42 completed studies that name it, 38%, have reported results: 2 posted them on ClinicalTrials.gov, 14 have a results paper linked to the registry record, and 0 did both. The other 26 show neither. Of all completed studies with a cognitive outcome, 46% have reported results.

More on the Digit Span Test and stroke

  • Every cognitive test in stroke trials: 1,233 studies
  • The Digit Span Test in all clinical trials: 1,629 studies

The Digit Span Test in other conditions

  • Dementia and Alzheimer's181
  • Mild cognitive impairment169
  • Depression and bipolar disorder143
  • Aging, frailty and exercise129
  • Cancer107
  • Brain injury and concussion98
  • Parkinson's disease86
  • Anxiety, PTSD and OCD72
  • Schizophrenia and psychosis66
  • Healthy volunteers64
  • Obesity and diabetes64
  • Sleep and sleep disorders63
  • Pain and fatigue61
  • Cognitive impairment and decline60
  • Cardiovascular disease59
  • ADHD58

Other tests in stroke trials

  • Trail Making Test156
  • Verbal Fluency110
  • Stroop Color-Word Test105
  • Picture Naming Test99
  • Cancellation Test75
  • Verbal Learning63
  • Symbol Coding61

How the studies are counted

For each test family, the census runs ClinicalTrials.gov's own outcome search for the family's names and reads every study first posted by the day the family was counted. These studies were read on 10 November 2026. A study counts once on a page, however many tests it names. Counts for a test cover every version of the task under any of its names, so a page can count studies that used a commercial version.

The census adds two things to each record and changes nothing in it: which outcome list names the test (primary, then secondary, then other), and the condition groups, matched on the study's condition names and MeSH terms. A study can fall in several groups; one whose only condition is cognitive impairment or decline falls in “Cognitive impairment and decline”. Studies that name only instruments outside the library count in every total and share but are not listed.

A second read on 10 November 2026 added each study's overall status, whether results are posted, its intervention types, the countries of its sites and the time frame of the outcome that names each test. A time frame counts by the latest time point it names: “Baseline, 12 and 24 weeks” is 24 weeks, a single visit is within a day, and one that names no duration, such as “end of treatment”, is left out of the timings.

A third read on 10 November 2026 added the papers the registry links to each study: those its sponsor lists as reporting results, and those PubMed links to it through the study's NCT number. A study has a results paper when one of them came out in or after the month of its primary completion and PubMed does not class it as a protocol, review or comment. A paper that never gives the NCT number is not linked, so some studies counted as reporting neither did publish.

Source: ClinicalTrials.gov, a database of the U.S. National Library of Medicine, which does not endorse these pages. Every study line is in the data release 2.1.0, and the explorer's own file is clinical-trials-studies.json.

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