Clinical trials data
Trail Making Test in anxiety, PTSD and OCD trials: 69 registered studies
Every registered anxiety, PTSD and OCD study on ClinicalTrials.gov that names the Trail Making Test in an outcome measure: how often it is a primary outcome, the tests named with it, how large the studies are and when they measure it.
- Registered anxiety, PTSD and OCD studies name it in an outcome measure
- 69
- Name it in a primary outcome, 35%
- 24 of 69
Tests named in the same studies
- 1
Digit Span Test30 studies, 13 as a primary outcome
- 2
Verbal Fluency27 studies, 13 as a primary outcome
- 3
Verbal Learning22 studies, 10 as a primary outcome
- 4
Stroop Color-Word Test22 studies, 6 as a primary outcome
- 5
Symbol Coding12 studies, 6 as a primary outcome
- 6
Category Fluency8 studies, 5 as a primary outcome
- 7
Continuous Performance Test8 studies, 5 as a primary outcome
- 8
Card Sorting Test (Berg)7 studies, 3 as a primary outcome
- 9
Letter-Number Sequencing Task7 studies, 3 as a primary outcome
- 10
N-Back Task5 studies, 2 as a primary outcome
A test as a primary outcomeOnly in secondary or other outcomes
Studies by start year
A test as a primary outcomeOnly in secondary or other outcomes
Show as a table
| Start year | Studies | A test as a primary outcome |
|---|---|---|
| 2000 | 0 | 0 |
| 2001 | 0 | 0 |
| 2002 | 0 | 0 |
| 2003 | 0 | 0 |
| 2004 | 0 | 0 |
| 2005 | 0 | 0 |
| 2006 | 0 | 0 |
| 2007 | 0 | 0 |
| 2008 | 1 | 0 |
| 2009 | 1 | 0 |
| 2010 | 1 | 0 |
| 2011 | 3 | 1 |
| 2012 | 3 | 1 |
| 2013 | 1 | 1 |
| 2014 | 0 | 0 |
| 2015 | 3 | 3 |
| 2016 | 2 | 1 |
| 2017 | 6 | 1 |
| 2018 | 7 | 3 |
| 2019 | 4 | 2 |
| 2020 | 4 | 1 |
| 2021 | 10 | 2 |
| 2022 | 1 | 0 |
| 2023 | 8 | 3 |
| 2024 | 6 | 3 |
| 2025 | 4 | 1 |
| 2026 | 4 | 1 |
Phases and study sizes
By phase
- Early phase 13 studies, 1 as a primary outcome
- Phase 210 studies, 1 as a primary outcome
- Phase 2/31 studies, 0 as a primary outcome
- Phase 34 studies, 0 as a primary outcome
- Phase 41 studies, 0 as a primary outcome
- Not applicable44 studies, 18 as a primary outcome
- Observational6 studies, 4 as a primary outcome
Participants per study
- Not applicable62 median, 30 to 96
Show as a table
| Phase | Studies with a size | Median | Middle half |
|---|---|---|---|
| Not applicable | 44 | 62 | 30 to 96 |
When anxiety, PTSD and OCD trials measure it
Latest time point of each outcome
- Within a day9 outcomes, 1 as a primary outcome
- Up to 4 weeks12 outcomes, 4 as a primary outcome
- 1 to 3 months24 outcomes, 7 as a primary outcome
- 3 to 6 months13 outcomes, 6 as a primary outcome
- 6 to 12 months4 outcomes, 2 as a primary outcome
- 1 to 2 years1 outcomes, 1 as a primary outcome
- Over 2 years1 outcomes, 0 as a primary outcome
- No duration given5 outcomes, 3 as a primary outcome
A test as a primary outcomeOnly in secondary or other outcomes
64 of the 69 outcome measures give a duration. A single visit counts as within a day.
Status, results, interventions and countries
Status
- Recruiting12 studies, 4 as a primary outcome
- Not yet recruiting2 studies, 0 as a primary outcome
- Active, not recruiting2 studies, 1 as a primary outcome
- Completed34 studies, 15 as a primary outcome
- Stopped early8 studies, 1 as a primary outcome
- Status unknown11 studies, 3 as a primary outcome
What they test
- Behavioral31 studies, 14 as a primary outcome
- Drug18 studies, 3 as a primary outcome
- Device11 studies, 3 as a primary outcome
- Dietary supplement3 studies, 1 as a primary outcome
- Diagnostic test1 studies, 1 as a primary outcome
- Radiation1 studies, 1 as a primary outcome
- Other10 studies, 3 as a primary outcome
- None given2 studies, 1 as a primary outcome
Intervention types as registered. A study can list several; observational studies often list none.
Where their sites are
- United States27 studies, 7 as a primary outcome
- Canada11 studies, 4 as a primary outcome
- China3 studies, 2 as a primary outcome
- Spain3 studies, 2 as a primary outcome
- Denmark2 studies, 1 as a primary outcome
- France2 studies, 0 as a primary outcome
- Ireland2 studies, 0 as a primary outcome
- Portugal2 studies, 1 as a primary outcome
- Taiwan2 studies, 0 as a primary outcome
- Hong Kong1 studies, 0 as a primary outcome
- Hungary1 studies, 0 as a primary outcome
- Israel1 studies, 0 as a primary outcome
20 countries in all. A study with sites in several counts in each; 4 list no site.
Reported results
Completed studies with results posted on ClinicalTrials.gov, a results paper the registry links to the study, or both.
Completed anxiety, PTSD and OCD studies that name the Trail Making Test: 15 of 34, 44%
Every completed study with a cognitive outcome: 3,626 of 7,953, 46%
| Results | Completed anxiety, PTSD and OCD studies that name the Trail Making Test | Every completed study |
|---|---|---|
| Results on ClinicalTrials.gov and a paper | 3, 9% | 776, 10% |
| Results on ClinicalTrials.gov only | 8, 24% | 1,139, 14% |
| A results paper only | 4, 12% | 1,711, 22% |
| Neither | 19, 56% | 4,327, 54% |
The 69 studies
69 studies match. 24 name the Trail Making Test in a primary outcome. Median size 67 participants. Median time to the primary outcome: 13 weeks.
Loading 69 studies; the filters turn on when they arrive.
2026 is partly planned starts.
Show as a table
| Start year | Studies | As a primary outcome |
|---|---|---|
| 2000 | 0 | 0 |
| 2001 | 0 | 0 |
| 2002 | 0 | 0 |
| 2003 | 0 | 0 |
| 2004 | 0 | 0 |
| 2005 | 0 | 0 |
| 2006 | 0 | 0 |
| 2007 | 0 | 0 |
| 2008 | 1 | 0 |
| 2009 | 1 | 0 |
| 2010 | 1 | 0 |
| 2011 | 3 | 1 |
| 2012 | 3 | 1 |
| 2013 | 1 | 1 |
| 2014 | 0 | 0 |
| 2015 | 3 | 3 |
| 2016 | 2 | 1 |
| 2017 | 6 | 1 |
| 2018 | 7 | 3 |
| 2019 | 4 | 2 |
| 2020 | 4 | 1 |
| 2021 | 10 | 2 |
| 2022 | 1 | 0 |
| 2023 | 8 | 3 |
| 2024 | 6 | 3 |
| 2025 | 4 | 1 |
| 2026 | 4 | 1 |
Library tests named most
Largest condition groups
Phases
Participants
Lead sponsor: industry 4, NIH 1, other 64. Interventional 63, observational 6.
As a primary outcomeSecondary or other outcomeThe Trail Making Test
The studies, newest registration first
Each number opens the study's record on ClinicalTrials.gov.
| Study | Start | Phase | Conditions | Participants | Lead sponsor | Status | Library tests named, with the latest time point |
|---|---|---|---|---|---|---|---|
| NCT07765355 | Start2025 | PhaseNot applicable | ConditionsDepression and bipolar disorder, Anxiety, PTSD and OCD | Participants60 | Lead sponsorOther | StatusRecruiting | Library tests named
|
| NCT07755839 | Start2026 | PhaseNot applicable | ConditionsDepression and bipolar disorder, Cancer, Anxiety, PTSD and OCD | Participants60 | Lead sponsorOther | StatusNot yet recruiting | Library tests named
|
| NCT07735910 | Start2026 | PhaseNot applicable | ConditionsMild cognitive impairment, Depression and bipolar disorder, Sleep and sleep disorders, Anxiety, PTSD and OCD | Participants60 | Lead sponsorOther | StatusRecruiting | Library tests named
|
| NCT07665840 | Start2025 | PhaseNot applicable | ConditionsDepression and bipolar disorder, Sleep and sleep disorders, Anxiety, PTSD and OCD | Participants67 | Lead sponsorOther | StatusCompleted | Library tests named
|
| NCT07393672 | Start2026 | PhasePhase 2 | ConditionsAnxiety, PTSD and OCD, Pain and fatigue | Participants104 | Lead sponsorOther | StatusRecruiting | Library tests named
|
| NCT07309302 | Start2025 | PhaseNot applicable | ConditionsDepression and bipolar disorder, Anxiety, PTSD and OCD | Participants64 | Lead sponsorOther | StatusRecruiting | Library tests named
|
| NCT06885996 | Start2026 | PhasePhase 2 | ConditionsAnxiety, PTSD and OCD | Participants76 | Lead sponsorOther | StatusNot yet recruiting | Library tests named
|
| NCT06831916 | Start2025 | PhasePhase 2 | ConditionsAnxiety, PTSD and OCD, Pain and fatigue | Participants104 | Lead sponsorOther | StatusCompleted | Library tests named
|
| NCT06804629 | Start2023 | PhaseNot applicable | ConditionsAnxiety, PTSD and OCD | Participants68 | Lead sponsorOther | StatusCompleted | Library tests named
|
| NCT06777693 | Start2024 | PhaseNot applicable | ConditionsDepression and bipolar disorder, Anxiety, PTSD and OCD | Participants24 | Lead sponsorOther | StatusRecruiting | Library tests named
|
| NCT06769243 | Start2023 | PhaseNot applicable | ConditionsAnxiety, PTSD and OCD | Participants30 | Lead sponsorOther | StatusCompleted | Library tests named
|
| NCT06569849 | Start2024 | PhaseNot applicable | ConditionsAnxiety, PTSD and OCD, Pain and fatigue | Participants60 | Lead sponsorIndustry | StatusStatus unknown | Library tests named
|
| NCT06542419 | Start2024 | PhaseNot applicable | ConditionsDepression and bipolar disorder, Anxiety, PTSD and OCD | Participants24 | Lead sponsorOther | StatusCompleted | Library tests named
|
| NCT06429956 | Start2024 | PhaseNot applicable | ConditionsDepression and bipolar disorder, Anxiety, PTSD and OCD | Participants93 | Lead sponsorOther | StatusRecruiting | Library tests named
|
| NCT06273527 | Start2024 | PhasePhase 2/3 | ConditionsDepression and bipolar disorder, Anxiety, PTSD and OCD | Participants128 | Lead sponsorOther | StatusRecruiting | Library tests named
|
| NCT06236919 | Start2024 | PhaseNot applicable | ConditionsDepression and bipolar disorder, Anxiety, PTSD and OCD | Participants160 | Lead sponsorOther | StatusRecruiting | Library tests named
|
| NCT06063265 | Start2023 | PhaseNot applicable | ConditionsAnxiety, PTSD and OCD | Participants120 | Lead sponsorOther | StatusCompleted | Library tests named
|
| NCT06032377 | Start2023 | PhaseNot applicable | ConditionsDepression and bipolar disorder, Sleep and sleep disorders, Anxiety, PTSD and OCD | Participants275 | Lead sponsorOther | StatusRecruiting | Library tests named
|
| NCT05967962 | Start2023 | PhaseNot applicable | ConditionsAnxiety, PTSD and OCD | Participants248 | Lead sponsorOther | StatusCompleted | Library tests named
|
| NCT05964062 | Start2023 | PhaseNot applicable | ConditionsAnxiety, PTSD and OCD | Participants30 | Lead sponsorOther | StatusStatus unknown | Library tests named
|
| NCT05964049 | Start2023 | PhaseNot applicable | ConditionsAnxiety, PTSD and OCD | Participants30 | Lead sponsorOther | StatusStatus unknown | Library tests named
|
| NCT05793736 | Start2023 | PhaseNot applicable | ConditionsDepression and bipolar disorder, COVID-19 and long COVID, Anxiety, PTSD and OCD, Pain and fatigue | Participants17 | Lead sponsorOther | StatusCompleted | Library tests named
|
| NCT05760729 | Start2021 | PhaseObservational | ConditionsMild cognitive impairment, Depression and bipolar disorder, Anxiety, PTSD and OCD | Participants75 | Lead sponsorOther | StatusStatus unknown | Library tests named
|
| NCT05595421 | Start2019 | PhaseNot applicable | ConditionsAnxiety, PTSD and OCD | Participants18 | Lead sponsorOther | StatusCompleted | Library tests named
|
| NCT05289258 | Start2021 | PhaseNot applicable | ConditionsDepression and bipolar disorder, Cancer, Anxiety, PTSD and OCD | Participants123 | Lead sponsorOther | StatusRecruiting | Library tests named
|
Questions, answered from the data
How many anxiety, PTSD and OCD trials use the Trail Making Test?
69 registered anxiety, PTSD and OCD studies on ClinicalTrials.gov name it in an outcome measure, 24 of them in a primary outcome: 10% of the condition's 692 studies with a cognitive outcome, against 14% of all of them. It is the 4th most named test in anxiety, PTSD and OCD trials.
Which tests do anxiety, PTSD and OCD trials use with the Trail Making Test?
The Digit Span Test (30 studies), Verbal Fluency (27 studies) and Verbal Learning (22 studies).
When do anxiety, PTSD and OCD trials measure the Trail Making Test?
Half of the primary outcomes that name the Trail Making Test are measured within 13 weeks of the start, and the middle half from 5 weeks to 6 months. 21 primary outcomes give a duration.
How many completed anxiety, PTSD and OCD trials that use the Trail Making Test have reported results?
15 of the 34 completed studies that name it, 44%, have reported results: 11 posted them on ClinicalTrials.gov, 7 have a results paper linked to the registry record, and 3 did both. The other 19 show neither. Of all completed studies with a cognitive outcome, 46% have reported results.
How the studies are counted
For each test family, the census runs ClinicalTrials.gov's own outcome search for the family's names and reads every study first posted by the day the family was counted. These studies were read on 10 November 2026. A study counts once on a page, however many tests it names. Counts for a test cover every version of the task under any of its names, so a page can count studies that used a commercial version.
The census adds two things to each record and changes nothing in it: which outcome list names the test (primary, then secondary, then other), and the condition groups, matched on the study's condition names and MeSH terms. A study can fall in several groups; one whose only condition is cognitive impairment or decline falls in “Cognitive impairment and decline”. Studies that name only instruments outside the library count in every total and share but are not listed.
A second read on 10 November 2026 added each study's overall status, whether results are posted, its intervention types, the countries of its sites and the time frame of the outcome that names each test. A time frame counts by the latest time point it names: “Baseline, 12 and 24 weeks” is 24 weeks, a single visit is within a day, and one that names no duration, such as “end of treatment”, is left out of the timings.
A third read on 10 November 2026 added the papers the registry links to each study: those its sponsor lists as reporting results, and those PubMed links to it through the study's NCT number. A study has a results paper when one of them came out in or after the month of its primary completion and PubMed does not class it as a protocol, review or comment. A paper that never gives the NCT number is not linked, so some studies counted as reporting neither did publish.
Source: ClinicalTrials.gov, a database of the U.S. National Library of Medicine, which does not endorse these pages. Every study line is in the data release 2.1.0, and the explorer's own file is clinical-trials-studies.json.
The census counts Trail Making Test A and Trail Making Test B as one test family, so this page counts their studies together.
Run the Trail Making Test in your trial
Choose tests with a record in registered trials, and run them in a browser at every site, on the same version each visit.